Spine Care

A Comprehensive Guide to Anterolisthesis and its Implications

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Individuals who have experienced spinal or back trauma, suffered fractures, are going through spinal degeneration, or are dealing with a spinal condition have an increased risk of anterolisthesis, where a vertebra slips forward relative to the vertebra below it. Can healthcare providers help prevent and treat the condition?

Anterolisthesis

The spine consists of 33 individual bones or vertebrae stacked on one another. Anterolisthesis occurs when one vertebral segment slips forward over another. The condition can be mild, asymptomatic, or cause significant pain and neurological symptoms. Many different things, including osteoarthritis, osteoporosis, trauma, or a fracture, can cause this vertebral shifting. (Cedars Sinai, 2022) Spondylolisthesis is a general term for shifting a spinal vertebra over the one below it. It includes anterolisthesis, forward moving, and the less common retrolisthesis, or backward shifting.

Grades

Anterolisthesis is typically graded using the Meyerding scale, which assigns one of five grades according to how much slippage has occurred. These grades include:

Grade 1

  • 0 to 25% slippage

Grade 2

  • 25 to 50% slippage

Grade 3

  • 50 to 75% slippage

Grade 4

  • 75 to 100% slippage

Grade 5

  • More than 100% slippage or spondyloptosis

Grade 1 and 2 cases are generally mild, while grades 3, 4, and 5 are more severe. (Koslosky E., and Gendelberg D. 2020)

Symptoms

Anterolisthesis can lead to various symptoms, depending on the severity and if the surrounding spinal nerves have been affected. The most common complaints include:

  • Lower back stiffness
  • Lower back pain
  • Shooting pain into the leg
  • Weakness when standing or walking for a long time
  • Cramping in the leg muscles
  • Numbness or tingling in the leg that improves when sitting or bending forward (American Academy of Orthopaedic Surgeons, 2021)

Causes

Cases of anterolisthesis are also typically categorized based on what led to the condition. The most common causes include:

Degenerative anterolisthesis

  • Shifting occurs when arthritis (spondylosis) causes the spine’s joints and discs to deteriorate.
  • The degenerative version of the anterolisthesis is the most common, particularly in women and adults over 50.
  • African Americans tend to experience this condition at a higher rate than the general population. (American Academy of Orthopaedic Surgeons, 2021)

Isthmic anterolisthesis

  • Slippage is caused by a fracture in a portion of the spine called the pars, also known as a pars defect.

Congenital or Dysplastic anterolisthesis

  • Slippage is caused by a condition present at birth or spinal abnormality.

Traumatic anterolisthesis

  • Acute shifting of the vertebrae caused by a traumatic injury.

Pathologic anterolisthesis

  • Anterolisthesis occurs because of a bone disease like osteoporosis.

Iatrogenic – Postsurgical anterolisthesis

Diagnosis

Diagnosis begins with a subjective evaluation and a physical examination. During these, the healthcare provider will assess sensation, strength, and reflexes and will order one of several diagnostic tests, including:

X-rays

  • Visualizes the vertebrae in the spine and their position relative to those above and below.
  • Also provides a clear picture of spinal arthritis or disc degeneration.

Magnetic Resonance Imaging – MRI

  • Allows the spinal cord, nerves, muscles, and discs to be assessed for compression or damage.

Computed Tomography – CT scan

Treatment

Several factors determine how the condition is treated, including:

  • The grade of the slippage.
  • The cause.
  • The symptoms.
  • The presence of instability on a diagnostic test such as an X-ray.

Stable and mildly symptomatic cases are usually treated with a combination that can involve:

  • Physical therapy
  • Activity modification
  • Bracing
  • Nonsteroidal anti-inflammatory medications/NSAIDs like ibuprofen.
  • Spinal injections

In more severe cases in which spinal instability or significant neurological symptoms are present, surgery may be recommended. This commonly involves a spinal decompression or fusion procedure. The technique varies based on the surgeon’s preferences and anatomy. (Koslosky E., and Gendelberg D. 2020)

Prognosis

Most individuals with this condition don’t know they have it until it is found accidentally on an X-ray or an MRI for something else. Mild cases can cause minimal symptoms and can be well-managed with conservative treatments. Cases of unstable anterolisthesis or those with neurological compression often require surgical intervention. These surgeries restore stability to the spine and alleviate any pressure on the nerves. More than 85% of individuals who need surgery have a successful outcome. (American Academy of Orthopaedic Surgeons, 2021)

Self-Care and Management

For individuals experiencing pain, numbness, or tingling from anterolisthesis, getting symptoms evaluated by a healthcare provider is an important first step. The healthcare provider may suggest one of several management strategies, which include:

Core Strengthening

  • To alleviate symptoms, exercises targeting the core muscles in the hips, pelvis, abdomen, and lower back are recommended.
  • Formal physical therapy may also be recommended.

Over-the-counter Meds

  • A healthcare provider may suggest pain-relieving medications like ibuprofen or naproxen to reduce soreness.

Activity Modification

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Degenerative Disc Disease Treatment


References

Cedars Sinai. (2022). Anterolisthesis. www.cedars-sinai.org/health-library/diseases-and-conditions/a/anterolisthesis.html

Koslosky, E., & Gendelberg, D. (2020). Classification in Brief: The Meyerding Classification System of Spondylolisthesis. Clinical orthopaedics and related research, 478(5), 1125–1130. doi.org/10.1097/CORR.0000000000001153

American Academy of Orthopaedic Surgeons. (2021). Adult spondylolisthesis in the low back. orthoinfo.aaos.org/en/diseases–conditions/adult-spondylolisthesis-in-the-low-back

Hospital for Special Surgery. (2023). Spondylolisthesis. www.hss.edu/condition-list_spondylolisthesis.asp

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The information herein on "A Comprehensive Guide to Anterolisthesis and its Implications" is not intended to replace a one-on-one relationship with a qualified health care professional or licensed physician and is not medical advice. We encourage you to make healthcare decisions based on your research and partnership with a qualified healthcare professional.

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