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Integrative Nutraceutical Approach To Dyslipidemia | Part 2

By
Dr. Alex Jimenez
-

Introduction

In the cardiovascular system, the heart’s main purpose is to pump blood throughout the entire body and to transport nutrients, hormones, and oxygen to the necessary musculoskeletal tissues and organs that need to do their job properly. When there are pathogens that enter the body, whether it is a poor lifestyle or poor nutrition that can cause the body to develop chronic illnesses, it can cause damage to the cardiovascular system. Some of the cardiovascular disease risk factors like dyslipidemia can disrupt the body’s blood flow throughout the body. In this 2 part series, we will be taking a look at what nutraceuticals are used to dampen the effects of dyslipidemia. In part 1, we discussed what dyslipidemia is, its symptoms, and how chronic inflammatory macro-and micronutrients can affect the cardiovascular system. By referring patients to qualified and skilled providers who specialized in cardiovascular services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

What Does Dyslipidemia Do To The Body?

In part 1, dyslipidemia is where the lipid levels in the blood are either too high or too low in the bloodstream. As research shows when individuals are getting a routine blood test from their primary healthcare provider, they are unaware that they may have dyslipidemia. If it gets severe or untreated, dyslipidemia can lead to other cardiovascular diseases like coronary artery disease and peripheral artery disease.

 

Dyslipidemia Factors

Research shows that dyslipidemia is an imbalance of lipids in the body that can cause a variety of disorders that can affect the body and can be classified into five categories. When there is an imbalance of lipids in the bloodstream, it is due to many factors that can cause dyslipidemia to go unnoticed until it is severe and it leads to cardiovascular disease with severe complications. These factors can be:

 

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

Stem cells* or HCTP (human cellular tissue products) are used in regenerative cellular treatments that are located both nationally and internationally affiliated clinics and distribution organizations. HCTP‘s main job is to help boost the body’s own natural healing process while also repairing and regenerating damaged cells, tissues, and organs back to their original state in the body.

Nutraceuticals For Dyslipidemia

Surprisingly there are many ways to lower dyslipidemia and even lower cholesterol for the heart. Research shows that the role of nutraceuticals has the ability to lower LDL-C (low-density lipoprotein cholesterol) and when it is combined with a lipid-lowering diet can even lower inflammation, oxidative stress, cardiovascular diseases, and improve immune response. Some of the nutraceuticals that can help lower dyslipidemia include:

 

Red Yeast Rice

Used in traditional Chinese medicine, red yeast rice is a diet staple in Asia. Studies have found that red yeast rice has been used as an alternative to statin therapy for individuals who have mild to moderate hypercholesterolemia. Other studies have shown that red yeast rice contains lovastatin and can help lower cholesterol levels by making sure that the intestines don’t absorb the cholesterol and are secreting the cholesterol out of the body through the stool.

 

Berberine

 

Since hyperlipidemia and dyslipidemia are two of the major risk factors for cardiovascular diseases, berberine can actually dampen the effects of these two risk factors from rising in the body. Studies have found that berberine has been used in Chinese medicine and can actually treat many different conditions like type 2 diabetes and hypertension in the body. Other studies also found that berberine has a great impact on lowering total cholesterol, LDL-C, HDL, and triglycerides in the body.

 

Pomegranate

Pomegranates are filled with antioxidants that can help lower cardiovascular diseases. Since all berries and fruits that contain polyphenols help lower the risk of inflammation in the body, consuming pomegranates in juice form or by eating the fruit itself does wonder for the body. Studies have shown that concentrated pomegranate juice can help improve the lipid profiles of diabetics that have hyperlipidemia. By adding pomegranates into a heart-healthy diet can provide the necessary nutrients for the body and lower the risk of cardiovascular disease.

Research has been shown that pomegranate has a huge amount of beneficial properties that can help the body not only lower inflammation in the body with its antioxidants but with more than 100 phytochemicals that can help lower the risk of dyslipidemia from rising. Other beneficial properties that pomegranate can provide include:

 

Conclusion

By incorporating some of these nutraceuticals into a heart-healthy diet can help lower cardiovascular diseases. By making small changes to a person’s lifestyle, eating whole nutritional food, taking multi-vitamins, and exercising can provide the individual a new outlook in life and even get rid of ailments that have caused them pain. When there are unwanted pathogens that can affect the body and the organs causing chronic symptoms rise over time making the person’s life miserable. When they start making these small changes in their life they can recover their sense of fulfillment in the world pain-free.

 

References

Bertuccioli, Alexander, et al. “Berberine and Dyslipidemia: Different Applications and Biopharmaceutical Formulations without Statin-like Molecules-a Meta-Analysis.” Journal of Medicinal Food, U.S. National Library of Medicine, 23 Aug. 2019, pubmed.ncbi.nlm.nih.gov/31441678/.

Burke, Frances M. “Red Yeast Rice for the Treatment of Dyslipidemia.” Current Atherosclerosis Reports, U.S. National Library of Medicine, Apr. 2015, pubmed.ncbi.nlm.nih.gov/25728312/.

Esmailzadeh, Ahmad, et al. “Concentrated Pomegranate Juice Improves Lipid Profiles in Diabetic Patients with Hyperlipidemia.” Journal of Medicinal Food, U.S. National Library of Medicine, 2004, pubmed.ncbi.nlm.nih.gov/15383223/.

Houston, Mark. “The Role of Nutraceutical Supplements in the Treatment of Dyslipidemia.” Journal of Clinical Hypertension (Greenwich, Conn.), U.S. National Library of Medicine, 17 Jan. 2012, pubmed.ncbi.nlm.nih.gov/22277145/.

Huizen, Jennifer. “Dyslipidemia: Causes, Symptoms, and Treatment.” Medical News Today, MediLexicon International, 17 May 2018, www.medicalnewstoday.com/articles/321844.

Koppen, Laura M, et al. “Efficacy of Berberine Alone and in Combination for the Treatment of Hyperlipidemia: A Systematic Review.” Journal of Evidence-Based Complementary & Alternative Medicine, SAGE Publications, Oct. 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5871262/.

Medical Professionals, Cleveland Clinic. “Red Yeast Rice and Plant Stanols for Cholesterol Reduction.” Cleveland Clinic, 2022, my.clevelandclinic.org/health/articles/17417-cholesterol-reduction-red-yeast-rice-and-plant-stanols.

Pappan, Nikos, and Anis Rehman. “Dyslipidemia.” StatPearls [Internet]., U.S. National Library of Medicine, 15 July 2021, www.ncbi.nlm.nih.gov/books/NBK560891.

Disclaimer

An Integrative Approach To Dyslipidemia | Part 1

By
Dr. Alex Jimenez
-

Introduction

The body has a way to deal with unwanted pathogens that enter the body. The immune system will go and send out the inflammatory cells to the area to deal with the pathogen. Sometimes if the pathogen is still in the body, it can attach to the blood cells and lipids that are traveling throughout the entire body. This can cause chronic issues like metabolic syndrome, metabolic endotoxemia, and even dyslipidemia to the body. In this 2 part series, we will be taking a look at what dyslipidemia is, its symptoms, and how chronic inflammatory macro-and micronutrients can affect the cardiovascular system. Part 2 will be taking a look at what nutraceuticals are used to dampen the effects of dyslipidemia. By referring patients to qualified and skilled providers who specialized in cardiovascular services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

What Is Dyslipidemia?

Dyslipidemia is a condition where the lipid levels in the blood are either too high or too low. Research shows that when there is an imbalance of lipids, which includes cholesterol, LDL-C (low-density lipoprotein cholesterol), triglycerides, and HDL (high-density lipoprotein) are causes the development of atherosclerosis and over time other cardiovascular diseases. The most common underlying reasons for dyslipidemia are:

 

Even though these are all correct protective/defense mechanisms that can help the body when acute illnesses are affecting the organ systems, they can turn into chronic illnesses over time when unwanted pathogens start to attach themselves to any of the organ systems and cause havoc to the body. Some of the most common reasons for these vascular responses include:

  • Chronic inflammatory macro- and micro-nutrient intake.
  • Chronic infections (all types including bacteria, virus, fungi, TB, and parasites).
  • Toxins, POPs (persistent organic pollutants), and heavy metals.
  • Metabolic, inflammatory, immune, toxic, and infectious endotoxemia.

 

Plasma Lipoproteins Are Important

Lipoproteins prevent infections, protect against toxins, and inflammatory nutrition as they are a component of innate immunity. Studies have found that lipoproteins are complex particles in the body that has a central core containing cholesterol esters and triglycerides and plasma lipoproteins can be divided into seven classes based on their lipid composition. Since all lipids and lipoproteins are anti-infective and protect against endotoxin and inflammation-induced vascular damage, they can all detoxify microbial LPS-lipopolysaccharide (gram-negative bacteria) and LTA-lipoteichoic acid (gram-positive bacteria) while binding to LPS to prevent LPS–induced activation of monocytes, macrophages, and pro-inflammatory cytokines.

 

 

Other studies have found that plasma lipoproteins are the essential vehicles for lipid distributions for the body’s cellular energy, structural requirements, and excreting out excess lipids out of the body. When there are imbalances in the lipoprotein metabolism that can contribute to metabolic diseases that can range from vascular inflammation to obesity and diabetes. However, as the lipids become modified they become vasculotoxic. The vascular system and heart become “ innocent bystanders” that are injured during the acute, correct defensive/protective responses which will induce atherosclerosis and chronic heart disease.

 

Dyslipidemia Symptoms

Since cardiovascular disease is involved in the cardiovascular system, dyslipidemia is one of the risk factors that can harm the body. Studies have found that dyslipidemia is considered a metabolic abnormality that can lead to a persistent increase in the plasmatic concentration of cholesterol and triglycerides, being the common cause of morbidity. Other research studies have found that many individuals are unaware that they have dyslipidemia unless it is severe and it is found in a routine blood test. Other symptoms that dyslipidemia can cause in the body include:

 

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

As a form of regenerative medicine, HCTP (human cellular tissue products) or stem cells* are used to help boost the body’s own natural healing process from injuries. Both national and international affiliated clinics and distribution organizations, use HCTP therapy to help repair and regenerate these damaged cells, tissues, and organs back to their original state, so the body can heal faster and the individual can continue on their wellness journey.

Chronic Inflammatory Macro- and Micronutrients

Since the gut plays a role in inflammation and is connected to other organ systems like the brain and the cardiovascular system, it can cause the body to develop chronic inflammation if it is not treated right away.  Studies have found that when there are structural changes in the intestinal epithelium that are due to diet alternations can become the results of increasing plasma lipoproteins to induce chronic low-grade inflammation in the body. An inflammatory diet will increase circulating endotoxin levels and with positive correlation with an increase in TC, LDL-C, TG, and decreasing in HDL-C and dysfunctional HDL. This will also correlate with obesity, WC( waist circumference), WHR (waist/hip ratio), insulin levels, IR (insulin resistance), T2 DM, inflammatory cytokines, NAFLD (non-alcoholic fatty liver disease). When this happens, metabolic endotoxemia will begin to cause a commotion.

 

Metabolic Endotoxemia & CHD

 

Research studies show that metabolic endotoxemia is a condition where lipopolysaccharide (LPS) levels are elevated despite the presence of any infections that are in the body. Since the gut microbiota signatures (GMS) act as important determinants in the pathogenesis of inflammatory induced obesity, CHD, atherosclerosis, and T2 DM, having metabolic endotoxemia can cause gut dysbiosis and chronic inflammatory diseases that stimulate the innate immune system, TLR4 in adipocytes and vascular tissue, activates NFkB increases inflammation, oxidative stress, and immune dysfunction. While LPS ( lipopolysaccharide) from gram-negative bacteria is the endotoxin from the cell wall that has a high affinity for chylomicrons and cross enterocyte barrier coupled with lipoproteins.

 

Conclusion

All in all, the body has a way to make sure that no unwanted pathogens attach themselves into the bloodstream and cause chronic issues to cause the body pain. When there are high levels or low levels of lipids that are causing cardiovascular disease risk factors to rise, it can cause the body to be dysfunctional. By incorporating heart-healthy and anti-inflammatory foods and supplements into the body, can provide the necessary nutrients to the body and its organ systems, it can dampen the effects of chronic diseases and the body can begin its recovery process.

 

References

Ama Moor, Vicky Jocelyne, et al. “Dyslipidemia in Patients with a Cardiovascular Risk and Disease at the University Teaching Hospital of Yaoundé, Cameroon.” International Journal of Vascular Medicine, Hindawi Publishing Corporation, 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5253480/.

Feingold, Kenneth R. “Introduction to Lipids and Lipoproteins.” Endotext [Internet]., U.S. National Library of Medicine, 19 Jan. 2021, www.ncbi.nlm.nih.gov/books/NBK305896/.

Fuke, Nobuo, et al. “Regulation of Gut Microbiota and Metabolic Endotoxemia with Dietary Factors.” Nutrients, MDPI, 23 Sept. 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6835897/.

Huizen, Jennifer. “Dyslipidemia: Causes, Symptoms, and Treatment.” Medical News Today, MediLexicon International, 17 May 2018, www.medicalnewstoday.com/articles/321844.

Li, Kang, et al. “Isolation of Plasma Lipoproteins as a Source of Extracellular RNA.” Methods in Molecular Biology (Clifton, N.J.), U.S. National Library of Medicine, 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6476197/.

Mohammad, Shireen, and Christoph Thiemermann. “Role of Metabolic Endotoxemia in Systemic Inflammation and Potential Interventions.” Frontiers, Frontiers, 11 Jan. 2021, www.frontiersin.org/articles/10.3389/fimmu.2020.594150/full.

Pappan, Nikos, and Anis Rehman. “Dyslipidemia.” StatPearls [Internet]., U.S. National Library of Medicine, 15 July 2021, www.ncbi.nlm.nih.gov/books/NBK560891.

Disclaimer

Body Stretching Fundamentals

By
Dr. Alex Jimenez
-
Happy young woman in activewear stretching towards foot while sitting on mat during workout in gym

 Stretching Fundamentals: Stretching benefits the body by keeping the muscles flexible, strong, healthy, and able to maintain optimal physical performance. As with any other discipline stretching correctly requires using the proper form, correct technique, and practicing regularly. The angles need to be accurate; the body has to move at the right speed and maintain correct posture. The focus should be moving the joint as little as possible as the muscle/s stretch and elongate.

Body Stretching Fundamentals

Stretching Fundamentals

Stretching should become a daily activity that turns into a healthy habit. The muscles need frequent maintenance from daily/nightly bending, twisting, reaching, carrying, and lifting work. This is especially true for individuals dealing with constant soreness, aches, pains, and problems with tight, tense, and stressed-out muscles. When the body is stressed, heart rate increases, and individuals tend to tighten up. Stretching benefits include:

  • Stress relief.
  • Increased muscle blood flow.
  • Increased body flexibility.
  • Helps joints move through their full range of motion.
  • Improves performance in physical activities.
  • Decreases soreness, aches, and pains.
  • Injury prevention.
  • Improves posture.
  • Improves sleep.
  • Preps the body for exercise and activities.
  • Improves mental health.

Human nature is to take the path of least resistance, which makes the body feel flexible and comfortable. This is a common reason individuals consider stretching unnecessary or too painful to engage in. However, stretching fundamentals need to be maintained as stretching carelessly or poorly can negatively affect other muscles and joints and worsen injuries/conditions. 

Guidelines

To stretch safely, it is recommended to do a proper warm-up, stretch slowly, working the right muscles and joints. The guidelines make stretching safer, more effective, and increase body awareness.

Warm-Up

  • Warming the muscles increases blood flow.
  • Warming up muscles before physical activity/workout is crucial for preventing injuries and maximizing effectiveness.
  • Stretching cold muscles activates a reflex that prevents overstretching, resulting in shortening and tightening of the muscles.
  • A healthy warm-up should consist of light cardio and dynamic stretches for the major muscle groups.
  • Dynamic stretching involves moving into and out of positions through a full range of motion rather than holding a stretch for a prolonged period.
  • Dynamic stretches are recommended to be held for 2-3 seconds for 4-6 repetitions.

Take It Slow

  • Stretching out too fast can make the body think that the muscle is about to get torn or injured.
  • To protect the muscle, it contracts, preventing it from reaching the full stretch.
  • This is why the correct technique needs to be observed.
  • A couple of degrees in the wrong direction can mean the difference between a healthy stretch and pulling a joint capsule causing injury.

Body Composition

Muscle Recovery

When engaged in physical activity, exercise, or working, microscopic tears are happening to muscle cells. Because of the body’s stress and fatigue, hormone and enzyme levels fluctuate, and inflammation increases. This helps in fat loss, increases metabolism, increases strength and muscle growth. However, these benefits only happen with proper recovery. Different types of recovery include:

Immediate Recovery

  • These are the quick moments’ in-between physical movements.
  • For example, the time between each stride when jogging.

Short-Term Recovery

  • This is the time between activities or sets of exercises.
  • For example, the rest periods between doing a heavy job or sprint intervals.

Training Recovery

  • This is the time between when one workout or job ends, and the next begins.

There is no one size fits all, as everyone’s body is different; it is recommended to consult with a trainer or fitness expert and experiment with what feels right.

  • For some individuals, 24 hours is enough.
  • For others, it can take 48 or 72 hours to feel fully recovered.
  • Other factors that affect recovery are:
  • Age
  • Fitness level
  • Work/exercise intensity
  • Diet
  • Sleep
References

Behm, David G, and Anis Chaouachi. “A review of the acute effects of static and dynamic stretching on performance.” European Journal of applied physiology vol. 111,11 (2011): 2633-51. doi:10.1007/s00421-011-1879-2

Freitas, S R et al. “Stretching Effects: High-intensity & Moderate-duration vs. Low-intensity & Long-duration.” International journal of sports medicine vol. 37,3 (2016): 239-44. doi:10.1055/s-0035-1548946

Hotta, Kazuki et al. “Daily muscle stretching enhances blood flow, endothelial function, capillarity, vascular volume and connectivity in aged skeletal muscle.” The Journal of physiology vol. 596,10 (2018): 1903-1917. doi:10.1113/JP275459

Kataura, Satoshi et al. “Acute Effects of the Different Intensity of Static Stretching on Flexibility and Isometric Muscle Force.” Journal of strength and conditioning research vol. 31,12 (2017): 3403-3410. doi:10.1519/JSC.0000000000001752

Emerging Nutraceuticals For Metabolic Cardiology | Part 2

By
Dr. Alex Jimenez
-

Introduction

The heart’s primary role in the cardiovascular system is to make sure that blood, nutrients, and hormones are being transported throughout the entire body. The cardiovascular system is consist of the arteries, veins, and blood vessels that are throughout the body and this system make sure to pump blood into the organs and tissues. When there are pathogens that cause the cardiovascular system to develop cardiac risk factors, it can cause many chronic issues over time and can potentially harm the body. In this 2 part series, we will be taking a look at what is diastolic dysfunction in the cardiovascular system and how different nutraceuticals can prevent heart disease from rising in the body. Part 1 took a look into what is cardiac metabolism and how HCTP can help renew the cardiovascular system. By referring patients to qualified and skilled providers who specialized in cardiovascular services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

What Is Diastolic Dysfunction?

The diastolic function requires more cellular energy than systolic contraction as higher concentrations of ATP are required to activate calcium pumps necessary to facilitate cardiac relaxation and diastolic filling. Studies show that diastolic dysfunction is a collective number of issues from hypertension, diabetes, age, and left ventricular hypertrophy that causes increased levels of cardiac oxidative stress and cardiac ROS in the heart.

 

Surprisingly, diastolic dysfunction is more common in women with hypertension, IHSS, MVP, and infiltrative cardiomyopathy, and the best way to know the early signs of myocardial failure due to diastolic despite the adequate systolic function in the heart. The energetic imbalance of diastolic heart failure is characterized by an increase in energy demand and a decrease in energy production, transfer, and substrate utilization resulting in an ATP deficit. The biopsies of heart tissue in heart failure
patients reveal diminished quantities of ATP in the mitochondria and studies show that diastolic heart failure occurs when the left ventricle is unable to accept adequate volumes of blood.

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

*Stem cells or HCTP (human cellular tissue products) are used in therapeutic regenerative treatments that affiliated clinics and distribution organizations (both international and national) provide for anyone that needs treatment. HCTP therapy utilizes HCTP to help repair and regenerate damaged cells, tissues, and organs back to their original state. As research studies continue to look into HCTP therapy, the result shows that HCTP can help rescue damaged heart cells and regenerate new heart muscle cells after the individual has been affected by cardiovascular diseases. Part 1 explains more about how HCTP can help repair damaged heart cells.

Nutraceuticals For Heart Disease

 

Surprisingly though there are nutraceuticals that can help dampen the effects of heart disease and help improve diastolic function to be regulated at normal levels. Studies have shown that even though cardiovascular disease ranks as the most common health issue, by providing several heart-healthy food and dietary supplements has been shown to protect against the development of cardiovascular diseases. Some of the nutraceuticals that can help lower the risk of heart disease are:

  • CoQ10
  • L-carnitine
  • D-ribose

 

CoQ10

Studies have shown that CoenzymeQ10 or CoQ10 can help decrease levels of neurodegenerative diseases, fibromyalgia, diabetes, and heart failure in the body. This essential compound has helped synthesized the mitochondrial inner membrane of the human body while also becoming the key component to transport electron chains in the cellular mitochondria, which is absolutely necessary for ATP production.

 

CoQ10 Effects

Since CoQ10 is a ubiquitous factor that is presented in the cell membranes and the mitochondria, research shows that CoQ10 has significant antioxidant and anti-inflammatory properties that can provide therapeutic results for individuals with cardiovascular diseases. Some of the beneficial effects that CoQ10 can offer to the heart include:

  • Reduces Lp(a)
  • Improves endothelial function
  • Decreases cholesterol/triglyceride levels
  • Increases HDL
  • Decreases FBS/HbA1c
  • Reduces lipoprotein (LDL) oxidation
  • Reduces systolic/diastolic blood pressure

 

L-carnitine

L-carnitine is a trimethylated amino acid-like cofactor for the transport of free long-chain fatty acids in the mitochondrial matrix where beta-oxidation occurs for cellular energy production. L-carnitine was originally isolated from meat in 1905 and it plays a crucial role in metabolism as it was discovered in 1955. Studies have shown that when patients are undergoing hemodialysis will often have carnitine deficiencies, which will result in cardiac dysfunction. However, like CoQ10, carnitine deficiency is usually not a factor in a healthy, well-nourished population consuming adequate animal protein.

 

L-carnitine Effects

Some of the beneficial factors that L-carnitine can provide to the body is that it actually plays an important role in transporting long-chain fatty acids from the cytoplasm into various tissues in the body. Other beneficial effects that L-carnitine provides include:

  • Beta oxidation of fatty acids – in mitochondria
  • 60% of heart energy metabolism of fatty acids
  • Removal of lactic acid and other toxic metabolites from blood
  • Ammonia detoxification
  • Function as antioxidants
  • Next-generation – Aminocarnitines

 

D-ribose

The administration of D-ribose can help with the improvement in diastolic function as D-ribose is used by cells to manage cellular energy restoration. It helps replenish the body as the loss of purines in the ischemic situation can cause a slow process to replace the adenine pool. If D-ribose is not available energy pool, then it cannot be restored and the heart can take about 100 days to restore ATP via de novo synthesis. Studies have found that D-ribose is actually an essential component for the respiratory, skeletal, and nervous systems while providing beneficial effects to the heart.

 

D-ribose Effects

Research studies have found that D-ribose is a naturally occurring pentose carbohydrate that has beneficial properties by increasing cellular energy levels, improving function that follows ischemia, and dampening the effects of cardiovascular disease. Other beneficial effects that D-ribose can provide include:

  • Improves treadmill findings in patients with coronary artery disease
  • Better diastolic function, QOL, and functional status in chronic heart failure
  • Accelerates the recovery of systolic function post CABG
  • Speeds recovery of muscle ATP following anaerobic exercise
  • Enhances strength and endurance gain with weight training
  • Decreases free radical stress during anaerobic exercise
  • Benefit in fibromyalgia

 

Conclusion

All in all, nutraceuticals are beneficial by dampening the effects of diastolic dysfunction and cardiovascular diseases. When unwanted pathogens start attacking the body, cause many inflammatory problems that can turn into chronic issues over time, causing a person to be miserable. By finding the right kind of vitamins, eating the right foods, and regularly exercising can help the body and cardiovascular system be functional throughout the entire lifetime.

 

Reference

Jeong, Euy-Myoung, and Samuel C Dudley. “Diastolic Dysfunction.” Circulation Journal: Official Journal of the Japanese Circulation Society, U.S. National Library of Medicine, 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4861951/.

Kaneko, Mai, et al. “L-Carnitine Improved the Cardiac Function via the Effect on Myocardial Fatty Acid Metabolism in a Hemodialysis Patient.” Internal Medicine (Tokyo, Japan), The Japanese Society of Internal Medicine, 15 Dec. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6355401/.

Lalande, Sophie, and Bruce D Johnson. “Diastolic Dysfunction: A Link between Hypertension and Heart Failure.” Drugs of Today (Barcelona, Spain: 1998), U.S. National Library of Medicine, July 2008, www.ncbi.nlm.nih.gov/pmc/articles/PMC2713868/.

Li, Shuai, et al. “D-Ribose: Potential Clinical Applications in Congestive Heart Failure and Diabetes, and Its Complications (Review).” Experimental and Therapeutic Medicine, D.A. Spandidos, May 2021, www.ncbi.nlm.nih.gov/pmc/articles/PMC8005739/.

Martelli, Alma, et al. “Coenzyme Q10: Clinical Applications in Cardiovascular Diseases.” Antioxidants (Basel, Switzerland), MDPI, 22 Apr. 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7222396/.

Medical Professionals, Cleveland Clinic. “Stem Cell Therapy for Heart Disease.” Cleveland Clinic, 30 Jan. 2019, my.clevelandclinic.org/health/diseases/17508-heart-disease-stem-cell-therapy.

Shecterle, Linda M, et al. “Potential Clinical Benefits of D-Ribose in Ischemic Cardiovascular Disease.” Cureus, Cureus, 9 Mar. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC5943027/.

Sood, Brittany, and Michael Keenaghan. “Coenzyme Q10.” StatPearls [Internet]., U.S. National Library of Medicine, 19 Jan. 2022, www.ncbi.nlm.nih.gov/books/NBK531491/.

Sosnowska, Bozena, et al. “The Role of Nutraceuticals in the Prevention of Cardiovascular Disease.” Cardiovascular Diagnosis and Therapy, AME Publishing Company, Apr. 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5418215/.

Zozina, Vladlena I, et al. “Coenzyme Q10 in Cardiovascular and Metabolic Diseases: Current State of the Problem.” Current Cardiology Reviews, Bentham Science Publishers, 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6131403/.

Disclaimer

The Emerging Frontier In Metabolic Cardiology | Part 1

By
Dr. Alex Jimenez
-

Introduction

The heart’s purpose in the cardiovascular system is to make sure that oxygen-riched blood, nutrients, and hormones are being pumped and transported throughout the body and into the muscle tissues and organs that need it. When there are pathogens that enter into the bloodstream, it can cause many risk factors to the cardiovascular system, it can lead to chronic symptoms over time if it is not treated right away. In this 2 part series, we will be taking a look at cardiac metabolism and how HCTP can help renew the cardiovascular system. Part 2 will be discussing what is diastolic dysfunction in the cardiovascular system and how different nutraceuticals can help prevent heart disease from rising. By referring patients to qualified and skilled providers who specialized in cardiovascular services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

What Is Cardiac Metabolism?

 

Since the heart’s job is to make sure that blood is pumping throughout the body, studies have found that the network for cardiac fuel metabolism contains an intricate set of interacting pathways that produces endpoint results for both ATP-producing and non-ATP-producing energy. However, when there are pathogens that are affecting the cardiac metabolism it can lead to chronic conditions like congestive heart failure. Research studies have shown that congestive heart failure is an energy-starved heart and is associated with metabolic changes in the body, it can cause a progressive impairment of cardiac and musculoskeletal high energy phosphate production in the heart. This will decrease ATP concentration causing serious defects in cellular metabolism and causing pulsation of the cellular structure in the heart muscles. With the roles of ATP vs. oxygen in myocyte of the cellular structure can also play their parts when dealing with modulating cardiac metabolism as a therapeutic approach to heart failure.

 

Cellular Mitochondria

Also known as the powerhouse of cells, the cellular mitochondria contain about 3500 – 5000 mitochondria, and the myocyte contains 35% of the entire cell. Research shows that the cellular mitochondria can help take the food that a person eats and turn it into energy for the cells can use. This helps ATP to formed in mitochondria and transfer to the cytosol to supply energy to the cell. There are 2 functions that the cellular mitochondria provide for the body while making sure that the cellular structure is healthy. The mitochondrial respiration is not all oxygen, that is converted to CO2 and water in the body but contains about 3-5% of oxygen, which are toxic free radicals. Mitochondrial DNA is more similar to bacterial DNA unlike nuclear DNA and provides defensive mechanisms that are just emerging and have proven to be very useful for tracing genetic lines.

 

Heart Disease

With 100,000 cases of new-onset chronic heart failure that are continuing to pop up around the world, research shows that heart disease can be numerous conditions that can affect the heart muscle. Some of the conditions with chronic heart disease actually depend on the symptoms of the heart disease a person may have. However, some of the common symptoms that can happen to the heart include nutritional factors like fast foods to mitochondrial failure in the body’s cellular structure. Even inflammation in the body is one of the symptoms of heart disease. For many individuals, there is a biochemical/metabolic connection to heart disease, since each of the organ systems is connected to each other and there is ATP nutriceutical support that can help lower the risk for heart disease.

 

Bioenergetics & The Heart

 

When there is dysfunctional energy in diseased hearts, angina, chronic heart failure, PTCA, CABG can cause heart risk factors to rise in the body, causing unwanted issues to affect a person. Chronic coronary artery disease with ischemia and/or silent ischemia can cause severe energy deprivation to occur. Any intervention that will slow the rate of ATP degradation and speed-up recovery rate will minimize heart damage and enhance cardiac function since chronic heart failure is energy-starved causing about 30% of all energy lost to the heart. This will cause low intra-myocardial ATP and reduced myocardial contraction but through bioenergetic therapy and even regenerative medicine can help the myocardial tissue may be restored significantly by oral supplements like Coenzyme Q10, Carnitine, D-Ribose to restore ATP dynamics in the heart.

 

HCTP & The Heart

 

Known throughout the world as *stem cells, HCTP or human cellular tissue products can help repair the damaged heart muscles from cardiovascular diseases. There is still more research being done with HCTP and its uses as a form of regenerative medicine as research shows that HCTP is nature’s own transformer and when the body is injured, HCTP is injected into the damaged heart muscle and repairing the damaged heart cells to be turned into new heart muscles. However, nationally and internationally affiliated clinics and distribution organizations are authorized to use HCTP in their practices since it has to be FDA-approved. Other research studies have shown that HCTP can help alleviate morbidity and mortality symptoms for patients that are dealing with heart damage from a variety of insults that has affected the heart.

 

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

HCTP therapy is a form of regenerative therapy that utilizes HCTP (human cellular tissue products) or stem cells* to help repair and regenerate damaged tissue, cells, and organs back to their original state. HCTP is used in affiliated clinics and distribution organizations (both international and national) that provided regenerative therapy to individuals that are dealing with chronic issues that are affecting their bodies.

Conclusion

All in all, the cardiovascular system makes sure that the heart is doing its job pumping blood throughout the entire body and keeping it functional. When there are unwanted risk factors that are affecting the heart, it can cause chronic symptoms to develop in the body over time and cause serious damage to the heart. By utilizing nutraceuticals, therapeutic treatments to alleviate the chronic symptoms that are damaging the heart, the body can recover and the cardiovascular system can continue to do its job.

 

References

Hare, Joshua M, and Sandra V Chaparro. “Cardiac Regeneration and Stem Cell Therapy.” Current Opinion in Organ Transplantation, U.S. National Library of Medicine, Oct. 2008, www.ncbi.nlm.nih.gov/pmc/articles/PMC3966209/.

Kolwicz, Stephen C, et al. “Cardiac Metabolism and Its Interactions with Contraction, Growth, and Survival of Cardiomyocytes.” Circulation Research, 16 Aug. 2013, www.ahajournals.org/doi/10.1161/CIRCRESAHA.113.302095.

Medical Professionals, Cleveland Clinic. “Stem Cell Therapy for Heart Disease.” Cleveland Clinic, 3 Jan. 2019, my.clevelandclinic.org/health/diseases/17508-heart-disease-stem-cell-therapy.

Newman, Tim. “Mitochondria: Form, Function, and Disease.” Medical News Today, MediLexicon International, 8 Feb. 2018, www.medicalnewstoday.com/articles/320875.

Rosano, Giuseppe Mc, and Cristiana Vitale. “Metabolic Modulation of Cardiac Metabolism in Heart Failure.” Cardiac Failure Review, Radcliffe Cardiology, Aug. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6125709/.

Staff, Mayo Clinic. “Heart Disease.” Mayo Clinic, Mayo Foundation for Medical Education and Research, 9 Feb. 2021, www.mayoclinic.org/diseases-conditions/heart-disease/symptoms-causes/syc-20353118.

Disclaimer

Hip Sprain

By
Dr. Alex Jimenez
-
Physiotherapist with screen and mask giving a hip massage. Reopening with physiotherapy safety measures in the Covid-19 pandemic. Osteopathy, therapeutic chiromassage

The hips are highly active joints. Hip sprains are rare but do occur. A hip sprain is caused by tearing or stretching the ligaments that surround the hip and join the bones to each other. This is different from a hip strain, which is an injury to the muscles and is generally caused by over-use of the hip flexor muscles and tendons, causing them to tear. Hip sprains usually happen after a fall or a sudden twisting motion, which can occur during sports or an accident.

Individuals involved in sports that require quick stops, body shifting, and sudden direction changes, like soccer, football, basketball, tennis, volleyball, etc., have an increased risk. Most hip sprains can be effectively treated with conservative treatments like self-massage, rest, ice, and nonsteroid anti-inflammatory medications. For more severe cases, physical therapy and chiropractic can treat the condition.

Hip Sprain

Hip Sprain Symptoms

  • Tenderness in the hip increases when lifting the thigh.
  • Cramping sensation/s in the muscles of the upper leg.
  • Swelling in the hip or thigh
  • Bruising in the hip or thigh.
  • Sudden pain in the hip or pelvis.
  • Sharp pain in the hip or pelvis.
  • Pain that worsens when walking, running, or stretching the hip muscles.
  • Loss of strength in the front of the groin.
  • Tugging or pulling sensation.
  • Limping.

Diagnosis

The doctor or chiropractor will:

  • Look into medical history.
  • Inquire about symptoms.
  • Inquire about activities that could cause symptoms.
  • Perform a physical examination.
  • Ask the individual to perform a variety of movements to determine what type of injury has been sustained.
  • Other conditions could cause radiating pain.
  • Pain in one or both hips might not have anything to do with the hips but a pinched nerve root in the lower back.
  • Sciatica can develop when certain nerve roots in the lower back are irritated or compressed, causing symptoms to travel down the sciatic nerve and radiate around the pelvis and leg.
  • X-rays can help rule out hip stress fractures, which can have similar symptoms.
  • MRI or CT scans are used to see if any soft tissue damage has occurred.

Hip Sprain Treatment

  • Treatment usually begins with over-the-counter pain medications and anti-inflammatories to reduce swelling and relieve pain.
  • Resting the hip will help prevent further damage.
  • Applying ice will help prevent tissue damage and reduce swelling.
  • It is recommended to use an ice pack several times a day for the first 48 hours after an injury.
  • Once the swelling goes down, a chiropractor and physical therapy team will create a personalized treatment plan that includes:
  • Adjustments.
  • Exercise therapy.
  • Posture training.
  • Stretching.
  • Massage.

Treatment/Rehabilitation Objectives

  • Reduce inflammation.
  • Relax muscle spasms.
  • Strengthen weakened muscles.
  • Improve joint mobility.

Individuals will be shown how to prevent the risk of sprains in the future. This includes:

  • Avoiding exercising when the body is tired
  • Wearing proper footwear and protective equipment
  • Warming up properly before exercise/physical activities.

Depending on the severity of the sprain, surgery could be the last resort to repair the ruptured or torn ligaments.

Body Composition

Realistic Goals

Not seeing results after putting in the work through exercise and diet can be frustrating. Setting realistic goals can help when results are not showing.

Realistic Fat Loss

  • Do not expect actual fat loss without being in a caloric deficit.
  • The body needs to use more energy than the amount of food/energy taken in; otherwise, excess energy/food gets stored, primarily as adipose tissue.
  • Total Daily Energy Expenditure or TDEE is necessary to set a realistic caloric deficit to achieve measurable fat loss.
  • There are caloric deficit variations, but most doctors, dieticians, trainers, and fitness experts agree that a caloric deficit of around 500 calories a day that equals to about 3,500 calories a week will result in a pound of fat loss per week.
  • One pound of fat a week lost might seem slow, but the one pound of fat is a real pound removed.
  • The long-term goal is not to fall back into unhealthy habits and develop and maintain new healthy ones.
References

Brantingham JW, Globe GA, Cassa TK, et al. A single-group pretest posttest design using full kinetic chain manipulative therapy with rehabilitation in the treatment of 18 patients with hip osteoarthritis. Journal of Manipulative and Physiological Therapy 2012; 33(6): 445-57.

Kamali, Fahimeh and Esmaeil Shokri. The effect of two manipulative therapy techniques and their outcome in patients with the sacroiliac joint syndrome. Journal of Bodywork and Movement Therapies. 2012; 16: 29-35.

McMorland G, Suter E, Casha S, du Plessis SJ, Hurlbert RJ. Manipulation or microdiscectomy for sciatica? A prospective randomized clinical study. Journal of Manipulative and Physiological Therapeutics. 2010; 33(8): 576-584.

Tibor, Lisa M, and Jon K Sekiya. “Differential diagnosis of pain around the hip joint.” Arthroscopy: the journal of arthroscopic & related surgery: official publication of the Arthroscopy Association of North America and the International Arthroscopy Association vol. 24,12 (2008): 1407-21. doi:10.1016/j.arthro.2008.06.019

Wedro, Benjamin. “Hip Pain: Causes, Symptoms, Treatment Information and Diagnosis-eMedicineHealth.” www.emedicinehealth.com/hip_pain/article_em.htm.

Revolutionary Diagnosis Concepts For Cardiovascular Disease | Part 2

By
Dr. Alex Jimenez
-

Introduction

In the cardiovascular system, the heart’s primary role in the body is to pump blood into the arteries, veins, and blood vessels to be transported throughout the entire body, giving oxygen-riched blood and nutrients to each muscle tissue and organ system so that they are doing their job. These blood cells are making sure that the body is functional. When there are disruptors that can cause the body to develop chronic illnesses, it can disrupt the cardiovascular system with chronic illnesses if it is not treated right away. In this 2 part series, we will continue the discussion of diagnosis concepts for cardiovascular disease and take a look at risk factors that causes cardiovascular disease in the body. Part 1 took a look at the diagnosis concepts for cardiovascular disease. By referring patients to qualified and skilled providers who specialized in cardiovascular services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

What Is Cardiovascular Disease?

In the cardiovascular system, the heart makes sure that the blood is pumping and traveling all throughout the body. When there are unwanted pathogens that enter the body, it can cause an array of problems. Studies have shown that cardiovascular disease is a cluster of diseases that can affect the heart. Some of the risk factors can even help the development of atherosclerosis and this can be numerous factors which include:

 

CVD & Chest Pain Evaluation

As a number one cause of death in the US,  one of the symptoms that cardiovascular disease is chest pains. Since there are 60,000 miles of arteries in the human body, studies have found that chest pains and shortness of breath are common in cardiovascular diseases and that they can become a risk factor for future cardiovascular morbidity and mortality rate in the body. Exertional precordial or substernal chest pressure, tightness, or chest pain with or without radiation to arms, neck, and shoulders or back and associated with:

 

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

As a form of regenerative medicine, HCTP (human cellular tissue products) or stem cells* are used to help boost the body’s natural healing process. In the U.S., nationally affiliated clinics and distribution organizations use HCTP therapy for bone marrow transplants, while international affiliated clinics and distribution organizations use HCTP therapy for chronic illnesses to help repair damaged cells, tissues, and organs back to their original state in the body.

Risk Factors From CVD

There are many risk factors that correlate with cardiovascular disease as it still remains the second leading cause of death. Some of the risk factors that cardiovascular disease can cause the body to be dysfunctional due to age, weight, gender, or family history. Other risk factors include:

  • Coronary Artery Plaque Erosion
  • Coronary Heart Disease
  • Microalbuminuria
  • Plasma Viscosity

 

Coronary Artery Plaque Erosion

Studies have found that coronary artery plaque erosion can cause eroded lesions that have a few inflammatory cells that can cause damage to the artery veins. Not only that if it is not treated can cause morbidity, mortality, and loss of quality of life in the body. Other studies also found that plaque erosion is the primary cause of coronary thrombus in premenopausal women that can actually raise cholesterol.

 

About one-third of NSTEMI due to plaque erosion and this is a “white thrombus” due to superficial intimal erosion. When there is endothelial cell death and desquamation uncover the basement membrane collagen (hyaluronic acid and glycosaminoglycans) which lead to TLR 2 expression PMNs produce NETS (Netosis)(Necoptosis) which forms the scaffold for thrombus formation. NETS contain pathogens, proteases, histones, chromatin, proteins, and ROS. These superficial erosions are different from other plaque that contain more VSMC, ECM, and NETS but fewer lipids, macrophages, foam cells, and inflammatory cells, thus the activation of superficial erosions by NADPH oxidase, high fat diet, cholesterol crystals, and MPO.

 

Coronary Heart Disease

There exist over 400 coronary heart disease risk factors and mediators beyond the top 5 of hypertension, dyslipidemia, diabetes, smoking, and obesity. Studies have shown that coronary heart disease is a common heart condition that involves atherosclerotic plaque formation in the vessel lumen causing impairment to blood flow. With the infinite insults and coronary heart disease risk factors and mediators inducing only three finite responses of inflammation, oxidative stress, and vascular immune dysfunction, there are over 100 more genetic variants that can increase coronary heart disease including:

  • Genomics, SNP’s and epigenetics
  • Gender and age
  • Inflammation
  • Oxidative stress
  • Vascular immune dysfunction
  • Infections
  • Metabolic and nutritional
  • Toxins
  • Psychological and neurological
  • Sleep disturbances
  • Lack of exercise
  • Structural and hemodynamic
  • Hormonal

 

Microalbuminuria

Microalbuminuria is one of the earliest abnormalities in the vascular system and kidney that reflects endothelial dysfunction and increased vascular permeability. With a high correlation with progression to proteinuria, renal disease, LVH, and future CVD, CHD, MI, CHF, and CVA, studies have shown that microalbuminuria is a powerful predictor of cardiovascular disease and it is likely to develop into atherosclerotic vascular disease and renal impairment if it is not treated right away. Microalbuminuria can also trigger tubular RAAS activation via megalin/cubilin receptors and inflammatory/oxidative stress reaction with NFkB/AP-1.

 

Plasma Viscosity

When there is resistance to blood flow in a blood vessel and the blood viscosity decreases as shear rate increases ( non-Newtonian fluid due to RBC deformability and deaggregation), this is known as plasma viscosity. Studies have shown that when there is an increase in blood viscosity, it can cause acute infections with myocardial infarction and can decrease tissue perfusion, and initiate systemic vascular resistance response. Plaque viscosity can also worsen the outer wall of vascular branches and the inner wall of curves causing fibrinogen to bind RBC and induce aggregation. It is seen in atherosclerosis, hypertension, dyslipidemia, DM, metabolic syndrome, tobacco use, obesity, aging, hyperfibrinogenemia, polycythemia, thrombocytosis, elevated globulins, cryoglobulinemia, and male gender, causing LDL to be large enough to bind RBC while the HDL is smaller and cannot.

 

Conclusion

All in all, the cardiovascular system makes sure that the heart is pumping blood into the body and circulating throughout the entire system. When disruptors like cardiovascular disease start to cause problems to the body, it can lead to many heart-related diseases over time if it is not treated right away. By incorporating heart-healthy foods, exercising regularly, and changing lifestyle habits, the body can begin to feel better and function properly without any problems that can cause it to be dysfunctional.

 

References

Barnett, Lauren A, et al. “Chest Pain and Shortness of Breath in Cardiovascular Disease: A Prospective Cohort Study in UK Primary Care.” BMJ Open, BMJ Publishing Group, 25 May 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5726088/.

Lopez, Edgardo Olvera, et al. “Cardiovascular Disease.” StatPearls [Internet]., U.S. National Library of Medicine, 11 Aug. 2021, www.ncbi.nlm.nih.gov/books/NBK535419/.

Quillard, Thibaut, et al. “Mechanisms of Erosion of Atherosclerotic Plaques.” Current Opinion in Lipidology, U.S. National Library of Medicine, Oct. 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5676466/.

Shahjehan, Rai Dilawar, and Beenish S Bhutta. “Coronary Artery Disease.” StatPearls [Internet]., U.S. National Library of Medicine, 14 Nov. 2021, www.ncbi.nlm.nih.gov/books/NBK564304/.

Singh, Anurag, and Simon C Satchell. “Microalbuminuria: Causes and Implications.” Pediatric Nephrology (Berlin, Germany), Springer-Verlag, Nov. 2011, www.ncbi.nlm.nih.gov/pmc/articles/PMC3178015/.

Sloop, Gregory D, et al. “The Role of Blood Viscosity in Infectious Diseases.” Cureus, Cureus, 24 Feb. 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7096068/.

Virmani, R, et al. “Plaque Rupture and Plaque Erosion.” Thrombosis and Haemostasis, U.S. National Library of Medicine, Sept. 1999, pubmed.ncbi.nlm.nih.gov/10695476/.

Disclaimer

New Diagnosis Concepts For Cardiovascular Disease | Part 1

By
Dr. Alex Jimenez
-

Introduction

The heart plays an important role in the body by pumping blood into the arteries, veins, and blood vessels to be transported through every muscle tissue and organ system so that they are doing their job correctly. From the central nervous system to the gut system all the way to the endocrine system, blood cells are being transported and moving throughout the body to make it functional. When unknown pathogens or stressors start to enter the body, it can cause a major disruption to the body through chronic illnesses and symptoms that can cause the body to be dysfunctional. In this 2 part series, we will be taking a look at diagnosis concepts for cardiovascular disease. In part 2, we will continue to discuss the diagnosis concepts for cardiovascular disease and be taking a look at the risk factors that cause cardiovascular disease. By referring patients to qualified and skilled providers who specialized in cardiovascular services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

What Is The Cardiovascular System?

 

Since the heart plays an important part in the cardiovascular system by making sure that blood is pumping through the arteries and veins. Research shows that the cardiovascular system has an important function by getting oxygenated blood and nutrients throughout the entire body and removing waste out of the body as well. The body’s cellular structure actually depends on the cardiovascular system to keep things running smoothly. When disruptors like cardiovascular disease start affecting the heart, it can lead to many complications that can harm the body.

 

How To Prevent Heart Disease

Since heart disease is the number one cause of death in the US and studies have found that cardiovascular disease can cause mortality and morbidity in the body and can actually be one of the many factors for hypertension. The annual cost is 320 billion dollars for individuals that go through heart disease treatments in order to feel better. However, about 80 percent of heart disease ( heart attacks, angina, coronary heart disease, and congestive heart failure) can be prevented by non-surgical treatments like:

 

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

HCTP therapy is a form of regenerative medicine that helps speed up the body’s natural healing process. HCTP or human cellular tissue products is the correct term for stem cells* that international and nationally affiliated clinics and distribution organizations use to help repair damaged cells, tissues, and organs. HCTP therapy as a regenerative treatment can provide the help and needs to repair diseased cells that have been affected by chronic illnesses back to their original state in the body.

Diagnosing Cardiovascular Disease

Since cardiovascular disease is a collection of disorders that can affect the heart, it is important that individuals go to their primary healthcare providers to get their heart diagnosed to make sure that cardiovascular disease doesn’t progress further. Studies have found that diagnosing cardiovascular disease or any diseases that affect the body, assesses the prognosis of the disease by facilitating the specific markers of proteins and nucleic acids to implicate the regulation of the body’s metabolism, controlling blood circulation, and inflammation. The blood vessel has only 3 finite responses to an infinite number of insults:

 

Blood Vessels Are Innocent Bystanders

 

The blood vessel in the cardiovascular system responds acutely as a defense mechanism to internal and external insults that are “correct and normal” but these chronic insults result in a chronic exaggerated and dysregulated cardiovascular dysfunction with preclinical then clinical cardiovascular disease due to maladaptation. Research shows that many cardiovascular diseases can cause an overproduction of the blood vessel causing many chronic symptoms like vascular malformation, inflammation, or plaque build-up in the blood vessels. Since the cardiovascular system is the innocent bystander and the blood vessels are taking a beating from chronic disorders, the subsequent environmental-gene expression patterns can produce downstream mediators that damage the arteries. However, proper assessment, comprehension, prevention, and treatment of the top five and other 395 chronic heart disease risk factors and the downstream mediators, will reduce chronic heart disease.

 

Endothelial Dysfunction & Membrane Dysfunction

 

The endothelium is recognized as a smart barrier and key regulator for blood flow in micro-and macrovascular circulation in the heart. When there is endothelial dysfunction, studies have found that endothelial dysfunction can predispose the blood vessels to vascular lesions, inflammation, and other disorders that can affect the heart. Membrane dysfunction is when the body barriers and membranes protect cells and provide the initial interaction of the external infinite insults with the internal signaling mechanisms. Research studies have shown that mitochondrial disorders are considered the most frequent genetic diseases and can have a high incidence of cardiac involvement with metabolic disturbances. This will increase membrane permeability and dysfunction results in both abnormal intracellular and extracellular signaling mechanisms. This includes the endothelium, enterocyte, brain dysfunction, and all other cell membranes that can affect the cardiovascular system if they are dysfunctional.

Continuum Of Risk

There is a progressive continuum of risk within the chronic heart disease risk factors and mediators that affect the blood vessels in the heart can be leading initially to functional abnormalities (endothelial dysfunction) then to structural abnormalities ( VSMH, arterial stiffness, LVH, carotid IMT), and eventually to preclinical and clinical cardiovascular disease. The vascular system provides transport and integrative biological activity with cell dominance to deliver micronutrients, oxygen and engage in metabolism, communication, and excretion.

 

Risk Factors For Vascular Disease

It is important to measure sensitive indicators of endothelial dysfunction and vascular disease to determine if the risk factors and insults induce vascular responses with functional and/or structural abnormalities. Studies have shown that vascular disease is a circulatory problem that causes reduced blood flow through the arteries that can cause either thigh or calf pain during walking or exertion. Standard chronic heart disease risk factors that do not adequately identify at-risk individuals and early detection with aggressive treatment will reduce cardiovascular disease, chronic heart disease, and chronic heart failure. Other research studies have shown that vascular disease has been associated with multiple risk factors which include smoking, diabetes, prior coronary artery disease, and even a sedentary lifestyle. These risk factors if not treated or changed can cause vascular disease to progress further to chronic illnesses.

 

Conclusion

By figuring out the diagnosis of cardiovascular diseases and figuring out what it can cause to the body, is essential to know that changing a certain lifestyle is essential for optimal wellness. The cardiovascular system’s job is to make sure that blood is flowing throughout the body and transporting oxygen-riched blood, nutrients, and hormones to each of the organs. When there are disruptors that can affect the cardiovascular system and the body, it can cause many risk factors to pop up if it is not treated. By catching the risk factors early and changing a person’s lifestyle habits with functional medicine, the individual can being their wellness journey risk-free.

 

References

Barthelmes, Jens, et al. “Endothelial Dysfunction in Cardiovascular Disease and Flammer Syndrome-Similarities and Differences.” The EPMA Journal, Springer International Publishing, 6 June 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5545991/.

Bisaccia, Giandomenico, et al. “Mitochondrial Dysfunction and Heart Disease: Critical Appraisal of an Overlooked Association.” International Journal of Molecular Sciences, MDPI, 9 Jan. 2021, www.ncbi.nlm.nih.gov/pmc/articles/PMC7827742/.

Gul, Fahad, and Sean F Janzer. “Peripheral Vascular Disease.” StatPearls [Internet]., U.S. National Library of Medicine, 29 Apr. 2021, www.ncbi.nlm.nih.gov/books/NBK557482/.

Medical Professionals, Cleveland Clinic. “Cardiovascular System: Overview, Anatomy and Function.” Cleveland Clinic, 13 Sept. 2021, my.clevelandclinic.org/health/body/21833-cardiovascular-system.

National Center for Biotechnology Information (US). “The Heart and Blood Vessels.” Genes and Disease [Internet]., U.S. National Library of Medicine, 1 Jan. 1998, www.ncbi.nlm.nih.gov/books/NBK22227/.

Stewart, Jack, et al. “Primary Prevention of Cardiovascular Disease: A Review of Contemporary Guidance and Literature.” JRSM Cardiovascular Disease, SAGE Publications, 1 Jan. 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5331469/.

Thiriet, Marc. “Cardiovascular Disease: An Introduction.” Vasculopathies: Behavioral, Chemical, Environmental, and Genetic Factors, U.S. National Library of Medicine, 19 Feb. 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC7123129/.

Zemaitis, Michael R. “Peripheral Arterial Disease.” StatPearls [Internet]., U.S. National Library of Medicine, 9 Jan. 2022, www.ncbi.nlm.nih.gov/books/NBK430745/.

Disclaimer

Tremors and Spinal Cord Compression

By
Dr. Alex Jimenez
-
senior businessman with pain in neck working with laptop

Tremors are extremely rare, but they can result from spinal compression and not necessarily a brain condition like Parkinson’s disease. Tremors are abnormal, involuntary body movements with various causes, most of which are connected to the brain and not the spine. A study reports that more than 75% of individuals with Parkinson’s experienced a resting tremor, and about 60% experience tremors while moving. Sometimes the spine is the contributor caused by compression of the spinal cord.

Tremors and Spinal Cord Compression

Spinal Compression Study

A 90-year-old man was hospitalized after having tremors, with Parkinson’s being the initial diagnosis. The tremors progressed to the point where the man could not feed himself or walk without support. The case became the focus of a medical report published by physicians in the Department of Orthopaedic Surgery, Division of the Spine, Singapore Tan Tock Seng Hospital. Along with the tremors, symptoms progressed to:

  • Difficulty with fine motor skills like buttoning a shirt.
  • However, it was ruled out because the patient was not presenting with other Parkinson’s symptoms.
  • What was found from the symptoms was cervical spondylotic myelopathy, which is a spinal cord compression in the neck.
  • The compression was caused by a herniated disc impinging the spinal canal and compressing the spinal cord causing spinal stenosis.
  • The compression was resolved by having an ACDF surgical procedure.
  • An anterior cervical discectomy and fusion or ACDF procedure can help manage the condition.
  • An ACDF treats spinal cord compression by removing a degenerative or herniated disc in the neck.

Cervical Myelopathy

Causes of cervical spondylotic myelopathy include:

Common symptoms include:

  • Balance problems
  • Coordination problems
  • Tingling in the hands
  • Numbness
  • Weakness
  • Impairment of fine motor skills

Tremors as a symptom are rare.

Cervical Myelopathy vs. Parkinson’s Disease

There are cases where cervical spondylotic myelopathy and Parkinson’s disease symptoms can overlap. Studies have shown difficulties between the two diagnoses, as well as, individuals with Parkinson’s may exhibit symptoms similar to cervical spondylotic myelopathy that can include:

  • Weakness
  • Lack of coordination
  • Bowel dysfunction
  • Bladder dysfunction

Treatment Cervical Myelopathy Tremors

For individuals with cervical spondylotic myelopathy tremors, surgery can be used to help the condition. However, with cervical myelopathy, there is often some permanent damage. Individuals have shown that post-surgery and decompression, symptoms still present, maybe not as much, but there will be a need for a symptom management plan.

Prevention

The best way to prevent tremors associated with cervical spondylotic myelopathy is to minimize the strain on the spine that can lead to herniated discs and/or other spinal injuries. The discs in the spine degenerate, dry out and start cracking with age, increasing the risk of rupture. If a tremor develops, contact a doctor, spine specialist, or chiropractor to help diagnose the condition. These doctors can perform physical and neurological tests to determine the cause and treatment options.

Body Composition

Aging Health

Steady weight gain throughout life can lead to adult-onset diabetes. This is partly caused by having more body fat and progressive muscle loss. Loss of skeletal muscle mass is linked to insulin resistance that involves:

  • The less muscle is available, the less insulin sensitive the body becomes.
  • As insulin sensitivity decreases, the body becomes more resistant, increasing risk factors for type II diabetes.
  • This can lead to osteoporosis, where the old bone is reabsorbed more and less new bone is created.

Both men and women can experience decreased muscle mass that can lead to:

  • Thinner bones
  • Weaker bones
  • Increased risk of osteoporosis and severe injury from falls.

To help prevent these issues, it is recommended to:

  • Eat sufficient protein throughout the day.
  • It is recommended to space out protein intake across meals rather than consuming it all at once. This helps to ensure the proper amount is acquired.
  • Monitoring body composition regularly can help minimize muscle mass loss and fat mass gain as the body ages.
  • A regular strength training routine will help strengthen bones muscles and maintain optimal circulation.
References

Heusinkveld, Lauren E et al. “Impact of Tremor on Patients With Early Stage Parkinson’s Disease.” Frontiers in neurology vol. 9 628. 3 Aug. 2018, doi:10.3389/fneur.2018.00628

Jancso, Z et al. “Differences in weight gain in hypertensive and diabetic elderly patients primary care study.” The Journal of nutrition, health & aging vol. 16,6 (2012): 592-6. doi:10.1007/s12603-011-0360-6

Srikanthan, Preethi, and Arun S Karlamangla. “Relative muscle mass is inversely associated with insulin resistance and prediabetes. Findings from the third National Health and Nutrition Examination Survey.” The Journal of clinical endocrinology and metabolism vol. 96,9 (2011): 2898-903. doi:10.1210/jc.2011-0435

Tapia Perez, Jorge Humberto et al. “Treatment of Spinal Myoclonus Due to Degenerative Compression Myelopathy with Cervical Spinal Cord Stimulation: A Report of 2 Cases.” World neurosurgery vol. 136 (2020): 44-48. doi:10.1016/j.wneu.2019.12.170

Revolutionary Concept Treatments For Hypertension | Part 2

By
Dr. Alex Jimenez
-

Introduction

In the cardiovascular system, the heart’s main job is to make sure that blood is pumping throughout the entire body. What this does is that the blood cells are carrying all the nutrients and oxygen to all the organs and muscle tissues so that way everything is working properly. When there are stressful situations that are constantly rising a person’s blood pressure, it can cause chronic issues that can cause the body pain. Since everyone in the world deals with stressful situations and if they are not careful in lowering these stressors, it can raise their blood pressure to chronic levels. In this 2 part series, we will be looking at revolutionary concept treatments to treat hypertension from rising into the body. Part 1 was taking a look at how hypertension is being a marker for vascular dysfunction and how the interaction of microvascular disease and vascular remodeling affects the body. By referring patients to qualified and skilled providers who specialized in cardiovascular services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

Hypertension As A Marker For Vascular Dysfunction

In part 1, it talked about hypertension as the leading factor for cardiovascular disease and how it is originated from a combination of factors that can affect the body. When this happens, it can cause elevated blood pressure to be one of the many responses to endothelial dysfunction and vascular dysfunction. If it is not treated right away, the body can develop future cardiovascular risk factor events and target organ damage. All is not hopeless, due to treatments that can help reverse cardiovascular risk factors and treat hypertension through therapeutic treatments.

 

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

*Stem cells are another term for human cellular tissue products or HCTP that international and nationally affiliated clinics and distribution organizations used to help boost the body’s natural healing process. Even though in the U.S. HCTP therapy is used for bone marrow transplants, international affiliated clinics use HCTP therapy as regenerative medicine to help repair and regenerate damaged cells, tissues, and organs that have been affected by chronic illnesses.

Treatments For Hypertension

Surprisingly there are many ways to help lower hypertension in the body. Some individuals can take up meditation to calm the anxious mind and through rhythmic breathing can lower their blood pressure significantly. Other ways that can help lower blood pressure include:

  • Exercise
  • DASH diet
  • Hydrogen Sulfide
  • Sodium Restriction
  • Nutraceuticals

 

Exercise & Hypertension

 

Since hypertension has been known to affect about 25% of the world’s population, studies found that exercise training can reduce blood pressure in the body. Regular aerobic exercise helps lower blood pressure significantly and reduces chronic heart disease risk. Individuals that want to lower their blood pressure and feel good about themselves need a combination of aerobic and resistance training in order to achieve optimal fitness by doing it 60 minutes 4 times per week to reduce chronic heart disease and blood pressure. Not only that but the benefits of exercising regularly can:

  • Increase eNOS and NO
  • Improves ED
  • Increase IL-10 and reduce inflammation
  • Muscle VEGF protein increased 67%.(J of Hypertens 2010;28:1176)
  • Marked improvement in angiogenesis.

DASH Diet

The Dash Diet is known as the Dietary Approaches to Stop Hypertension and it is designed to help treat or prevent high blood pressure through healthy eating. For DASH-HF, it helps lower blood pressure as DASH but reduced TG and VLDL, increasing LDL size more without a change in LDL. Research studies show that long-term adherence to the DASH diet and having food substitutions within the diet help lower the risk for heart failure. By limiting CHO despite increased SFA can improve the lipid profile with DASH –HF can provide more MUFA and PUFA also improving lipids. Other studies also found that the DASH diet can be used to not only effectively reduce blood pressure but the food and nutrients from the diet can prevent and treat hypertension in the body.

 

Hydrogen Sulfide

Hydrogen Sulfide or H2S is from sulfate-reducing bacteria, dietary sulfur-containing amino acids, and from the enzymatic breakdown of homocysteine and cysteine that can help lower blood pressure in the body. Studies have found hydrogen sulfide is recognized as a gasotransmitter with protective effects for the cardiovascular system and when there are higher blood levels of sulfate and thiosulfate and polysulfides correlate with reductions in CVD and hypertension by inducing vasodilation and ROS scavenging.

 

 

Since H2S reacts with NO and nitrosothiols forming thionitrous acid, nitroso-persulfide, and nitroxyl which vasodilates, it also activates K channels, inhibits SNS, activates PKG1 alpha, and inhibits PDE 5. Studies also found that hydrogen sulfide is a blood pressure regulator and scavenger of reactive oxygen species while also reducing organ damage like stem cells*.

 

Sodium Restriction

A great way to lower hypertension in the body is to restrict sodium from any diet. Studies have found that the effects of dietary sodium restriction on diabetic individuals are remarkable as sodium restrictions significantly lower systolic and diastolic blood pressure in the body. Other studies also found that not only sodium restriction can decrease blood pressure and the incidences of hypertension in the body, but it can reduce morbidity and mortality in cardiovascular diseases. Some of the other functions that sodium restriction can do includes:

  • Improve HBP control in pharmacologically treated patients
  • Reduce CVD, CHD, CHF, CVA in all subjects, especially the obese
  • Reduce LVH, diastolic dysfunction, and vascular hypertrophy
  • Reduce renal disease and proteinuria
  • Improved effect with high K+, Mg++, and Ca++ intake (especially Na+ sensitive) (DASHI and II) (Montreal)
  • Improved effect with restriction of refined carbohydrates
  • Reduction in TOD is also independent of BP Reduction

 

Nutraceuticals

 

Nutraceuticals can actually help lower hypertension levels in the body. Research studies have found that different supplements and nutraceuticals contain antioxidant properties that lower blood pressure. Some of the nutraceuticals and supplements that can help lower hypertension include:

 

Conclusion

All in all, finding ways to lower blood pressure from the body is beneficial for anyone that wants to change their lifestyle. By making small changes to their lifestyle slowly can provide amazing results in their wellness journey. When providing the right kind of foods, therapy, or exercise to their lifestyle, a person can being to change how the way they look and if they have any ailments that hinder their way of life, can notice that their body is healing itself and they can get their life back together.

 

References

Al-Magableh, Mohammad R, et al. “Hydrogen Sulfide Treatment Reduces Blood Pressure and Oxidative Stress in Angiotensin II-Induced Hypertensive Mice.” Hypertension Research: Official Journal of the Japanese Society of Hypertension, U.S. National Library of Medicine, 7 Aug. 2014, pubmed.ncbi.nlm.nih.gov/25099489.

Carpio-Rivera, Elizabeth, et al. “Acute Effects of Exercise on Blood Pressure: A Meta-Analytic Investigation.” Arquivos Brasileiros De Cardiologia, Sociedade Brasileira De Cardiologia – SBC, May 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC4914008/.

Cicero, Arrigo F G, and Alessandro Colletti. “Nutraceuticals and Blood Pressure Control: Results from Clinical Trials and Meta-Analyses.” High Blood Pressure & Cardiovascular Prevention: the Official Journal of the Italian Society of Hypertension, U.S. National Library of Medicine, 19 Mar. 2015, pubmed.ncbi.nlm.nih.gov/25788027/.

Grillo, Andrea, et al. “Sodium Intake and Hypertension.” Nutrients, MDPI, 21 Aug. 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6770596/.

Ibsen, Daniel B, et al. “The Dietary Approach to Stop Hypertension (DASH) Diet Is Associated with a Lower Risk of Heart Failure: A Cohort Study.” European Journal of Preventive Cardiology, U.S. National Library of Medicine, 4 Jan. 2022, pubmed.ncbi.nlm.nih.gov/34983068/.

Levitan, Emily B, et al. “Consistency with the Dash Diet and Incidence of Heart Failure.” Archives of Internal Medicine, U.S. National Library of Medicine, 11 May 2009, www.ncbi.nlm.nih.gov/pmc/articles/PMC2682222.

Ren, Jingyi, et al. “Effect of Dietary Sodium Restriction on Blood Pressure in Type 2 Diabetes: A Meta-Analysis of Randomized Controlled Trials.” Nutrition, Metabolism, and Cardiovascular Diseases: NMCD, U.S. National Library of Medicine, 26 Feb. 2021, pubmed.ncbi.nlm.nih.gov/33838996/.

Staff, Mayo Clinic. “How to Make the Dash Diet Work For You.” Mayo Clinic, Mayo Foundation for Medical Education and Research, 25 June 2021, www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/dash-diet/art-20048456.

Disclaimer

New Concept Treatments For Hypertension | Part 1

By
Dr. Alex Jimenez
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Introduction

The heart’s job in the cardiovascular system is to make sure that blood is pumping through the veins, arteries, and blood vessels to each muscle tissue, organ, and making sure that everything is working properly. When a person is dealing with high blood pressure, it can cause harm to the body as there are many factors that can affect it. If it is not treated, the body can develop chronic illnesses over time and can harm each of the organ systems including the cardiovascular system. In this 2 part series, we will be taking a look at hypertension being a marker for vascular dysfunction and how the interaction of microvascular disease and vascular remodeling affect the body. Part 2 will look at new concept treatments to treat hypertension from rising into the body. By referring patients to qualified and skilled providers who specialized in cardiovascular services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

What Is Hypertension?

The blood vessels in the body have a finite number of responses to an infinite number of insults that can affect a person. The three finite responses that can cause the body to be dysfunctional are inflammation, oxidative stress, and vascular immune dysfunction. Research studies show that high blood pressure or hypertension is where there is a long-term force of the blood against the artery walls that are high enough to cause heart problems like heart disease. Hypertension is not a disease but is the “correct” chronic dysregulated vascular response with an exaggerated outcome from infinite insults to the blood vessels. There are infinite insults that are biomechanical like blood pressure and hemodynamic alterations and biohumoral, which are biochemical, metabolic, and nutritional.

 

This results in the subsequent environmental-gene expression patterns in which the vascular system is the innocent bystander, thus resulting in altered vascular biology, vasoconstriction, and hypertension. With these modulations of environmental insults and downstream disturbances of gene expression patterns is the key to the prevention and treatment of hypertension and cardiovascular disease.

 

Hypertension As A Marker For Vascular Dysfunction

Studies have found that hypertension is the leading risk factor for cardiovascular disease and that it originates from a combination of factors that can cause the blood pressure to rise. An elevated blood pressure is one of many responses of the blood vessel to endothelial dysfunction and vascular smooth muscle dysfunction. ( impaired microvascular function and structure ). The endothelial dysfunction and microvascular smooth muscle dysfunction precede the development of hypertension by decades if it is not treated.

 

Endothelial Dysfunction Predicts CVD & Hypertension

Endothelial dysfunction, as studies show, is an established response to cardiovascular risk factors and can cause the development of atherosclerosis. Not only that, but endothelial dysfunction is a very accurate predictor of future cardiovascular events (CVD) and target organ damage (TOD) such as CHD, MI, CVA, CRF, and CHF. All is not lost, as cardiovascular risk factors can be treated and endothelial dysfunction can be reversed with treatments like regenerative therapy.

 

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

As new treatments for chronic illnesses start to prove exceptional results, regenerative medicine has been rising up in treating individuals at the cellular level. Most individuals have heard of the term “stem cells”* but the correct term is human cellular tissue products or HCTP as most affiliated clinics and distribution organizations (both nationally and internationally) uses HCTP as regenerative therapy to help repair damaged cells, organs, and tissues back to their original state. Nationally here in the US, HCTP treatments are used for bone marrow transplants, however; international clinics in Colombia, use HCTP treatments to help repair diseased cells and damaged tissues in the body.

Microvascular Disease & Vascular Remodeling

Microvascular disease involves small resistance arteries, arterioles, capillaries, and post-capillary venules and about 100-300 um size arterioles are involved due to hypertension, DM, and obesity. Studies have found that microvascular disease is referring to the subset of disorders that are affecting the structure and function of the coronary microcirculation in the heart. In hypertension and many other cardiovascular risk factors like obesity and diabetes mellitus, there is an increase in MLR: media/lumen ratio and in essential or primary hypertension it is eutrophic remodeling, meaning that there is a rearrangement of normal material around a narrowed lumen and in DM, MS, obesity, and secondary forms of hypertension, it is known as hypertrophic remodeling: VSMC hypertrophy or hyperplasia.

 

 

Studies have shown that vascular remodeling is when there are alternations in the resistance vessel structures that are contributing to elevated systemic vascular resistance in hypertension. Vascular remodeling and rarefaction of arterioles can occur at the same time and lead to reduced tissue perfusion and oxygenation. Other factors that vascular remodeling does to the vessels in the heart include:

  • Reduced coronary flow reserve and dilation
  • An increase in the MLR in arterioles prior to the onset of hypertension. Once hypertension occurs then the MLR and BP parallel one another.
  • Due to integrins, ROS, inflammation, and vascular immune dysfunction.
  • An increased MLR of over 0.098 increased CV events in hypertension, especially if hypertrophic remodeling.
  • Correlation with retinal and subcutaneous arteries

 

The Interactions Between Microvascular Disease & Vascular Remodeling

When there are small resistance and pre-capillary arteries that are less than 100 um in size, maintain wall tensile stress by eutrophic remodeling inward without growth processes and this is due to the greatest myogenic response and constriction that decreases the lumen size. The larger arterioles that are 100 to 300 uM in size has a lower myogenic constrictive response which leads to the vascular media wall
hypertrophy with reduced lumen size and increased media to lumen ratio (MLR).

 

Microvascular adaptive mechanisms help protect fragile capillaries from excess pressure but necessarily reduce blood flow with a mismatch in local tissue demands and induce ischemia. And theses microvascular changes occur with  HLP, DM, and CRI in the body, while the endothelial dysfunction that leads to microvascular disease is secondary to inflammation, oxidative stress, and immune
vascular dysfunction. This will lead to an increase in aortic stiffness, thus increasing the pressure pulsatility in the vessels. Macrovascular changes can include large arterial stiffness with loss of arterial compliance, while also changing the abnormal vasomotor tone and the functional and structural network rarefaction decreased vasodilatory reserve and altered wall to lumen ratio. This means that both macrovascular and microvascular changes are independent predictors of cardiovascular events in hypertensive patients.

 

Conclusion

All in all, the heart’s job is to make sure that blood is pumping through the blood vessels, arteries, and veins throughout the body. When there are unwanted pathogens that start affecting the heart, it can cause many problems for the body and if it is not treated can be dangerous for the person. By lowering high blood pressure in the body with nutritious food or through therapeutic treatments, the body can begin to reverse the effects of cardiovascular disease risk factors from rising. By lowering the effects of cardiovascular disease factors, the body can function properly and the individual can start their wellness journey.

 

References

Carey, Robert M, et al. “Prevention and Control of Hypertension: JACC Health Promotion Series.” Journal of the American College of Cardiology, U.S. National Library of Medicine, 11 Sept. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6481176/.

Hadi, Hadi A R, et al. “Endothelial Dysfunction: Cardiovascular Risk Factors, Therapy, and Outcome.” Vascular Health and Risk Management, Dove Medical Press, 2005, www.ncbi.nlm.nih.gov/pmc/articles/PMC1993955/.

Renna, Nicolás F, et al. “Pathophysiology of Vascular Remodeling in Hypertension.” International Journal of Hypertension, Hindawi Publishing Corporation, 2013, www.ncbi.nlm.nih.gov/pmc/articles/PMC3736482/.

Staff, Mayo Clinic. “High Blood Pressure (Hypertension).” Mayo Clinic, Mayo Foundation for Medical Education and Research, 1 July 2021, www.mayoclinic.org/diseases-conditions/high-blood-pressure/symptoms-causes/syc-20373410.

Taqueti, Viviany R, and Marcelo F Di Carli. “Coronary Microvascular Disease Pathogenic Mechanisms and Therapeutic Options: JACC State-of-the-Art Review.” Journal of the American College of Cardiology, U.S. National Library of Medicine, 27 Nov. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6296779/.

Disclaimer

Squat Exercises Causing Low Back Pain

By
Dr. Alex Jimenez
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People doing squats without weighting exercise in gym. Concept of gym.

Squat exercises are highly effective, as they strengthen the back and core muscles, helping the prevention of injury. They can be done anywhere with or without equipment like weights and resistance bands and can be part of an aerobic workout. Squatting requires following proper form and posture. Using the improper form, adding too much weight too soon, overdoing it without enough recovery time can cause soreness, back pain, and injury. Having muscle soreness after performing squats is expected; however, if symptoms like chronic soreness, tingling, numbness, or sharp aches that come and go, begin to appear, it is recommended to consult a medical trainer, chiropractor, doctor, or spine specialist to evaluate the symptoms, and if necessary develop a treatment plan, as well as a prevention plan to continue exercising safely.

Squat Exercises Causing Low Back Pain

Squat Exercises

Squatting is a highly beneficial form of exercise. Athletes, trainers, coaches, and individuals just staying healthy use the technique as a part of their training and workouts. This is because squatting increases core muscle strength, increasing body power. Squat exercises benefits include:

Increased Flexibility

  • Improved strength and a range of motion allow the body to move flawlessly in various directions with minimal effort.

Increased Core Strength

  • All major muscles work together during a squat.
  • This increases muscle stabilization, maintains body balance, increasing core strength.

Injury Prevention

  • Squats work all leg muscles simultaneously, synchronizing the body.
  • This increases body stability decreasing the risk of injury.

Back Pain and Potential Injury

The spine is exposed and unprotected during a squat. This is where back pain and injury can happen. Potential causes include:

  • Not warming up/priming muscles properly.
  • Tight muscles and a limited range of motion.
  • Improper form and squatting technique.
  • Adding weight or loading too soon.
  • Weak core muscles.
  • Incorrect or improper footwear with inadequate arch support.
  • Weak ankle muscles are not used to the weight and shift, causing misalignment and awkward positioning.
  • Previous injuries to the lower back can cause a flare-up to the area and potentially worsen.

Prevention

Ways to troubleshoot and prevent back pain during squat exercises.

Warmup

  • Using a proper and effective warmup will ensure that the body is ready for the workout stress.
  • Priming each muscle is recommended. This could be:
  • Starting with glute work.
  • Then planks to activate the core.
  • Finish off with stretching and range of motion exercises.
  • A personal trainer can assist in creating a customized workout routine.

Starting Position

  • The feet should always face forward to protect the hips and knees when beginning a squat.
  • If the feet face at an angle, the form can be impacted, leading to back pain or collapsing arches.

Spinal Alignment

  • Maintaining a straight-ahead or upward gaze, which increases center awareness during squat exercises, can prevent the body from leaning forward and placing stress on the spine.
  • Only squat as far as possible, making sure to feel in control and maintain the form.
  • Squatting too deep can cause muscle strain leading to pain.
  • Focus on form, as it is more important than depth.

Joint mobility

  • Ankle mobility and stability are essential to balance and control.
  • If the ankle is compromised, the feet could lift off the floor, forcing the body to compensate, leading to strain and potential injuries.
  • Only squat as far as ankle stability allows.
  • Ankle flexibility exercises will help improve squat form.

Variations

A chiropractor or physical therapist will be able to evaluate spinal health, exercise form, and advise if there is an issue.

Body Composition

Achieve Health and Fitness Goals By Doing What You Enjoy

Don’t engage in workouts or fitness programs that make you miserable. Do workouts/activities that you enjoy and have fun doing. Exercise for the love of the body, keeping it healthy and in shape, not because there is a feeling of obligation.

  • Try and experiment with different workouts/physical activities to see and feel what works for you.
  • Individuals who don’t like lifting weights try using resistance bands or bodyweight exercises.
  • The same goes for nutrition. Don’t base diet and supplement choices on misperceptions about health.
References

Calatayud, Joaquín et al. “Tolerability and Muscle Activity of Core Muscle Exercises in Chronic Low-back Pain.” International journal of environmental research and public health vol. 16,19 3509. 20 Sep. 2019, doi:10.3390/ijerph16193509

Clark, Dave R et al. “Muscle activation in the loaded free barbell squat: a brief review.” Journal of strength and conditioning research vol. 26,4 (2012): 1169-78. doi:10.1519/JSC.0b013e31822d533d

Cortell-Tormo, Juan M et al. “Effects of functional resistance training on fitness and quality of life in females with chronic nonspecific low-back pain.” Journal of back and musculoskeletal rehabilitation vol. 31,1 (2018): 95-105. doi:10.3233/BMR-169684

Donnelly, David V et al. “The effect of the direction of gaze on the kinematics of the squat exercise.” Journal of strength and conditioning research vol. 20,1 (2006): 145-50. doi:10.1519/R-16434.1

Zawadka, Magdalena et al. “Altered squat movement pattern in patients with chronic low back pain.” Annals of agricultural and environmental medicine: AAEM vol. 28,1 (2021): 158-162. doi:10.26444/aaem/117708

Cardiovascular Disease & Diabetes Prevention

By
Dr. Alex Jimenez
-

Introduction

The body needs insulin to make sure that the blood glucose is making each of the systems inside work properly and provide energy as well. By regulating insulin in the body, it can help the body from having unwanted pathogens disrupting the organ systems and increasing blood glucose levels. However, the body is not perfect as it encounters situations where the body can become dysfunctional over time if it is not treated. Unwanted pathogens can actually enter the body and cause many chronic illnesses to develop over time causing pain and suffering to the individual. In this article, we will be taking a look at how cardiovascular disease and diabetes are linked and how to prevent these two from rising in the body. By referring patients to qualified and skilled providers who specialized in cardiovascular services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

How Cardiovascular Disease & Diabetes Are Linked?

 

When unwanted pathogens affect the body, a variety of chronic illnesses and conditions can pop up over time, even if the individual is healthy. Diabetes and cardiovascular diseases can work hand in hand by causing the blood glucose levels to rise in the bloodstream, while the arteries can have plaque build-up causing heart diseases to pop up. Research studies show that when the body has high blood glucose levels from diabetes, it can actually damage the blood vessels and the nerves that control the heart and over time lead to heart disease. Cardiovascular disease and diabetes are linked to each other through obesity, insulin resistance, and inflammation. Other studies have shown that amongst diabetics that obesity and type 2 diabetes are two of the major risk factors for cardiovascular disease and can increase the risk of heart failure in a person. Other conditions that diabetes and cardiovascular diseases are linked to include:

 

Insulin Resistance

 

Insulin resistance is an impaired biological response to insulin stimulation of targeted tissues as studies show. The study also showed that insulin resistance can impair glucose disposal and once it is progressed can lead to chronic conditions like diabetes, coronary heart disease, metabolic syndrome, and nonalcoholic fatty liver disease. Other studies have shown that as obesity and diabetes have reached epidemic proportions and with insulin resistance, it can cause an increase in blood glucose levels, and tissues and organs that require insulin will have excess amounts of glucose in their systems causing hyperinsulinemia to developed.

 

Metabolic Syndrome

Research studies have stated that metabolic syndrome is a cluster of disorders that can affect a person’s lifestyle which includes atherosclerotic cardiovascular disease, insulin resistance, and diabetes mellitus. Metabolic syndrome, when being assessed by physicians requires the measurement of waist circumference for patients. This is a simple but seldom performed procedure in general practice. The most essential components for the prevention and management of metabolic syndrome are measures to change diet and physical activity in order to achieve and sustain weight loss. Research shows that when metabolic syndrome is being diagnosed early, individuals can effectively employ a change of lifestyle and risk factor modifications to their bodies in order to live healthier.

 

Increased Gut Permeability

Since the gut microbiota contributes to host metabolism by several mechanisms including increased energy harvest from a healthy diet, modulation of lipid metabolism, altered endocrine function, and increased inflammatory tone. The gut microbiota could thus be considered to be an environmental factor that modulates obesity and other metabolic diseases. Studies have found that increased intestinal permeability can cause microbial translocation which can induce low-grade inflammation in various diseases. This means that when there are alterations in the intestinal permeability, intestinal
barrier function becomes compromised whereby access of infectious agents and dietary antigens to mucosal immune elements are facilitated, which may eventually lead to immune reactions with damage to pancreatic beta cells and can lead to increased cytokine production with consequent insulin resistance.

 

 

Other indications of an increased intestinal permeability as studies show when the gut barrier is compromised, toxins can seep out of the gut and into the bloodstream thus the immune system will start attacking the pathogens and cause low-grade inflammation. An increased gut permeability can lead to an increase of macromolecule being absorbed from the intestinal content resulting in systemic immune
responses and altering the signaling pathways influencing lipid and glucose metabolism.

 

Preventing CVD & Diabetes from Rising

There are many ways to prevent cardiovascular disease and diabetes from rising to dangerous levels in the body. Many individuals that want to get their life back in order ask for their primary health care providers to suggest to them a personalized diet that can help them in the long run. With each diet lifestyle, it can help successfully modify elevated postprandial blood glucose and its metabolic consequences. By finding the right nutritional diet, exercise, and lifestyle that works for individuals, they have a better chance to lower any chronic illnesses that they may have and can live life to the fullest.

 

Exercise

By finding the right kind of exercise routine or even starting out exercise is beneficial for a person to get moving and help alter the skeletal muscle metabolism and improves glucose uptake. By exercising regularly, the body will begin to feel much better since exercising can help reduce low-density lipoprotein, raise HDL while lowering blood pressure, reduce inflammation and oxidative stress. By incorporating exercise as a recovery process will benefit the body and the individual will notice that they are losing weight in a healthier way.

 

Eating Nutritious Food

Now exercising is only a third of the recovery process, as eating nutritious food that is filled with antioxidants, full of bright colors, and has the necessary vitamins and nutrients that the body needs. By making small changes to a person’s diet by swapping out the processed food with more fruits, vegetables, limiting the carbohydrates and oils in the food diet can provide the body a better chance to feel better. Eating nutritious food can even help the gut system by feeding the good bacteria and repairing the intestinal permeability back to normal. Plus one of the bonus points of eating nutritional food is that it can even lower the effects of cardiovascular diseases, regulate blood glucose levels and have antioxidant properties to lower inflammatory factors.

HCTP Research

Tony Robbins finds secret to eliminating back pain

HCTP therapy is a form of regenerative treatment that both internationally and nationally affiliated clinics and distribution organizations used to treat damaged cells, tissues, and organs by repairing them. HCTP therapy is beneficial for individuals who are in chronic pain as HCTP can help speed up the body’s own natural healing process to repair damaged cells.

Conclusion

All in all, cardiovascular disease and diabetes are two of the main factors to cause the body to be in chronic pain and be dysfunctional. By realizing that an unhealthy lifestyle can cause a chain reaction to inflammation, diabetes, and cardiovascular risk factors can lead the body to be in chronic pain over time. By incorporating a heart-healthy diet filled with nutritional food filled with antioxidants, vitamins, and minerals that provide beneficial properties to the body can lower these symptoms. With these changes, a person can begin their wellness journey with a better understanding on what causes them pain and begin to live life to the fullest.

 

References

Bischoff, Stephan C, et al. “Intestinal Permeability–a New Target for Disease Prevention and Therapy.” BMC Gastroenterology, BioMed Central, 18 Nov. 2014, www.ncbi.nlm.nih.gov/pmc/articles/PMC4253991/.

Freeman, Andrew M. “Insulin Resistance.” StatPearls [Internet]., U.S. National Library of Medicine, 10 July 2021, www.ncbi.nlm.nih.gov/books/NBK507839/.

Fukui, Hiroshi. “Increased Intestinal Permeability and Decreased Barrier Function: Does It Really Influence the Risk of Inflammation?” Inflammatory Intestinal Diseases, S. Karger AG, Oct. 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC5988153/.

Medical Professionals, NIDDKD. “Diabetes, Heart Disease, & Stroke.” National Institute of Diabetes and Digestive and Kidney Diseases, U.S. Department of Health and Human Services, Apr. 2021, www.niddk.nih.gov/health-information/diabetes/overview/preventing-problems/heart-disease-stroke.

Rochlani, Yogita, et al. “Metabolic Syndrome: Pathophysiology, Management, and Modulation by Natural Compounds.” Therapeutic Advances in Cardiovascular Disease, SAGE Publications, Aug. 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5933580/.

Swarup, Supreeya. “Metabolic Syndrome.” StatPearls [Internet]., U.S. National Library of Medicine, 30 Oct. 2021, www.ncbi.nlm.nih.gov/books/NBK459248/.

Wilcox, Gisela. “Insulin and Insulin Resistance.” The Clinical Biochemist. Reviews, U.S. National Library of Medicine, May 2005, www.ncbi.nlm.nih.gov/pmc/articles/PMC1204764/.

Zang, P-Y. “Cardiovascular Disease in Diabetes.” European Review for Medical and Pharmacological Sciences, U.S. National Library of Medicine, 2014, pubmed.ncbi.nlm.nih.gov/25070828/.

Disclaimer

Sports Specific Performance Training

By
Dr. Alex Jimenez
-
Young woman doing exercises with personal instructor in gym. Sport, athlete, training, healthy lifestyle and people concept.

Sports-specific performance training is an approach to develop an athlete’s full potential in their sport. This involves three different factors: physical, technical, and experience. Physical ability is the exercise physiology that consists of strengthening and conditioning the body to handle the conditions of the sport. This includes:

  • Strength
  • Power
  • Speed
  • Endurance
  • Mobility
  • Stability
  • Flexibility
  • Balance

Technical ability involves the skill sets needed for the sport. This includes:

  • Running
  • Jumping
  • Kicking
  • Throwing
  • Catching
  • Hitting
  • Sliding

And finally is the athlete’s experience. This takes the knowledge, combined with the physical and technical abilities brought together to perform at optimum levels. However, it all begins with physical ability that needs to be developed. Even naturally gifted individuals need to develop their physical ability.

Sports Specific Performance Training

Sports Specific Performance Training

Strength & conditioning objectives are to develop the whole athlete. This involves:

An athlete’s health takes into consideration their body composition and current or past injuries. Along with injuries, the athlete’s mobility, flexibility, and stability are examined to determine if these were among the contributors or conditions that caused or could lead to an injury. Strength & conditioning is used so an athlete can return to play and allow them to be more resilient to injuries. Maintaining the body’s health means:

  • Keeping track of nutrition by making healthy food choices.
  • Maintaining proper hydration levels.
  • Allowing the body to recover from training thoroughly.
  • Keeping the body loose and flexible through chiropractic sports massage or a personal training therapist.

Mobility, Flexibility, and Stability

If an athlete is mobile and flexible but not stable, it increases the risk of sustaining an injury. The same can be said of an athlete with stability but limited mobility.

Athletic Mindset

An athlete’s mindset can win or lose games.

  • Athletes are encouraged to push themselves to see what they are capable of, which relies on mental strength.
  • Athletes that doubt their ability become their own worst critics and hold themselves in low self-esteem tend to underperform or become overly cautious when competing.
  • This is where a sports psychologist can help an athlete overcome any confidence issues.

Athleticism

Developing athleticism involves strength, power, speed. These physical attributes allow athletes to perform within their technical and strategical abilities.

  • It is recommended to spend 10-15 minutes warming up with each sports-specific performance training session. The warm-up:
  • Primes for the athlete’s nervous system.
  • Increases blood flow to the muscles.
  • Prepares the joints for optimal function.

Warm-ups can consist of:

  • Foam rolling
  • Breathing drills
  • Static stretching
  • Corrective exercises
  • Movement preparation
  • Movement skills

Speed training addresses linear, lateral, and multi-directional speed. The objective is to keep athletes learning and developing better reaction skills while maintaining high-quality movement. Speed training can last 10 to 15-minutes with the number of repetitions.

Strength training follows an individualized system for each athlete based on an initial evaluation. The objective is to eliminate any weaknesses that an individual may have and develop functional strength, giving the athlete the ability to take that strength onto the field, court, mat, etc.

It is essential to understand how the body moves. Kinesiology and programming parameters involve – sets, repetitions, overall training volume, and the body’s response to the stimulus.

Body Composition

Exercise and Blood Pressure

Blood pressure typically rises naturally as the body ages.  The American Heart Association recommends individuals get at least 150 minutes of moderate-intense aerobic exercise or 75 minutes of vigorous aerobic activity each week. This can be split up into 30 minutes per day on at least five days a week or in 10 minute short sessions throughout the day.  Aerobic exercise can include:

  • Walking
  • Dancing
  • Running
  • Cycling
  • Hiking
  • Swimming

Resistance Training

Research suggests that resistance training with bands or weights can supplement aerobic exercise to reduce blood pressure. It is recommended to complete 2 to 4 sets of 8 to 12 repetitions for each major muscle group during workouts. It is recommended that resistance training be spaced out throughout the week to limit the potential muscle soreness that can lead to injury. Resistance training can include:

  • Weight machines like chest press, shoulder press, etc.
  • Free weights like dumbbells, barbells, etc.
  • Resistance band exercises
References

Bahr, R, and T Krosshaug. “Understanding injury mechanisms: a key component of preventing injuries in sport.” British journal of sports medicine vol. 39,6 (2005): 324-9. doi:10.1136/bjsm.2005.018341

Iaia, F Marcello et al. “High-intensity training in football.” International journal of sports physiology and performance vol. 4,3 (2009): 291-306. doi:10.1123/ijspp.4.3.291

Jeukendrup, Asker E. “Periodized Nutrition for Athletes.” Sports medicine (Auckland, N.Z.) vol. 47,Suppl 1 (2017): 51-63. doi:10.1007/s40279-017-0694-2

Kraemer, William J, and Nicholas A Ratamess. “Fundamentals of resistance training: progression and exercise prescription.” Medicine and science in sports and exercise vol. 36,4 (2004): 674-88. doi:10.1249/01.mss.0000121945.36635.61

Nagorsky, Eugen, and Josef Wiemeyer. “The structure of performance and training in esports.” PloS one vol. 15,8 e0237584. 25 Aug. 2020, doi:10.1371/journal.pone.0237584

The Gut’s Role In Cardiovascular Disease | Part 2

By
Dr. Alex Jimenez
-

Introduction

The body’s microbiome is a host of trillions of microorganisms that help form an ecosystem that interacts with the entire body system. Each of the systems inside the body like the musculoskeletal system, the gut system, the central nervous system, and the endocrine system each play a role in order for the body to function properly. When there are unwanted pathogens that start attacking each system, it can cause lots of problems to the body and over time can develop into chronic illnesses. In this 2 part series, we will be taking a look at how different organisms are associated with cardiovascular diseases and how to improve the gut’s microbiome health. Part 1 took a look at the body’s microbiome and how it plays a role in cardiovascular disease. By referring patients to qualified and skilled providers who specialized in cardiovascular services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

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The Gut Microbiome & Cardiovascular Disease

Since the gut is known to create a symbiotic relationship with its host, chronic illnesses can affect it and cause unwanted problems to not only the gut but also the entire body. Studies have found that when the gut goes through deleterious changes that cause an imbalance to the gut microbiota, it can impair the homeostatic mechanisms and activate multiple pathways that can trigger cardiovascular disease risk factors. Another study also found that when the gut microbiome is affected it can also cause bacterial translocation to be associated with the development of cardiac disorders that makes them potential triggers to the gut microbiome.

 

Organisms Associated With Cardiovascular Disease

Some of the organisms that are in the body can be associated with cardiovascular disease. Studies show that when these organisms are associated with cardiovascular diseases, they can cause impaired intestinal barrier function and the presence of bacterial products that they carry can be in the systemic circulation and heightened inflammatory state in the gut while also affecting the cardiovascular system. Some of the organisms include:

  • Lipopolysaccharide (LPS)
  • Occludin
  • Zonulin
  • Leaky Gut
  • Metabolic Endotoxemia

 

Lipopolysaccharide

 

Lipopolysaccharides (LPS) are large molecules found in gram‐negative bacteria. They are endotoxins, and if absorbed can elicit a strong immune response. The detection of antibodies against LPS reveals macromolecule‐sized endotoxin infiltration through the intestinal barrier into the systemic circulation.
Intestinal permeability can cause systemic inflammation through translocation of LPS. Studies have found that lipopolysaccharides may be involved in the process of atherothrombosis process since it is an interesting molecule that once it crosses the gut microbiota and enters the systemic circulation it will cause chronic inflammation and atherosclerosis, which is a cardiovascular disease.

 

Occludin

Occludin is part of the main component of proteins holding together the tight junctions. Research shows that intercellular tight junctions help regulate the counter interactions of occludin and provide highly polarized barriers for homeostatic maintenance. The detection of antibodies to occludin indicates that the tight junctions are breaking down.  Studies have found that occludin can help the tight junction with regulated maintenance but when chronic symptoms like oxidative stress are causing problems to occludin, it can cause damage to the gut and the intestinal barrier membrane.

 

Zonulin

Zonulin is a protein that regulates the permeability of the intestine and the detection of antibodies against zonulin indicates that the normal regulation of tight junctions is compromised. Research has found that zonulin expression is augmented in autoimmune conditions that are associated with tight junction dysfunction including celiac disease and cardiovascular disease. There are clues to the presence of an ongoing mechanism involved in damaging the intestinal barrier. Studies have also found that zonulin can possibly cause low-grade inflammation and degenerative disorders like coronary heart disease, stroke, and diabetes.

 

Leaky Gut

 

When the intestinal permeability is compromised with chronic illnesses that make holes in the intestinal walls, that is known as leaky gut. Research states that a leaky gut is caused when bad bacteria begin to cut holes and food particles and toxins start to leak out into the bloodstream. When that happens, the immune system will see these as pathogens and start to attack them causing irritation and inflammation. Leaky gut can even cause many chronic symptoms to the body that the bad bacteria outweighs the good bacteria and other symptoms that leaky gut can cause include:

 

Metabolic Endotoxemia

Metabolic endotoxemia is considered an important factor that is in developing many chronic illnesses that a person is dealing with. Research shows that when there are structural changes in the intestinal epithelium it can allow LPS into the bloodstream. LPS is common to trigger insulin resistance, obesity, diabetes, and endotoxemia increased during the fed and decreased during fasted state. This means that LPS concentration 2‐3X threshold defines metabolic endotoxemia which can dysregulate the inflammatory tone and trigger the body. Other factors that metabolic endotoxemia can do to the body are:

 

By lowering plasma LPS concentration, it could be a potent strategy for the control of metabolic diseases and the body can start to feel better.

 

How To Improve Gut Microbiome Health

 

There are many ways to help improve gut microbiome health. One of the ways that an individual can help improve their gut is by eating soluble fibers. Soluble fibers are found in oats, beans, apples, and citrus fruits that are digested by enzymes into short-chain fatty acids (SCFAs). SCFAs are the main metabolites that are produced by the large intestine microbiota and constitute approximately 5–10% of the energy source in healthy people. By increasing dietary fibers and prebiotics in the body can help the large intestine microbiota increase production of SCFAs. Other ways to help the gut is by:

  • Increase low‐mercury fish consumption
  • Increase in whole plant food
  • Avoid sugar and processed foods
  • Eat foods like onion, leek, garlic, and dandelion greens (prebiotics are the non-digestible oligofructose, inulin, galactooligosaccharides within these plants).
  • Fiber‐enriched diets improve insulin sensitivity in lean and obese diabetic subjects

 

HCTP Research

Tony Robbins finds secret to eliminating back pain

HCTP therapy is a form of regenerative treatment that both international and national affiliated clinics and distribution organizations use for individuals that are dealing with chronic pain. HCTP therapy helps the body’s natural healing process by regenerating damaged cells, tissues, and organs back to their original state.

Conclusion

All in all, the heat and gut microbiomes are connected to make sure that the body is functioning properly. When there are unwanted pathogens that are attacking one or the other, it can cause chronic illnesses that can cause inflammation and heart diseases to rise up. By incorporating a healthy diet that is rich in fiber, can help lower inflammation and repair the gut microbiota. With a healthy gut, the body can begin to heal and repair itself with the necessary nutrients that it needs in order to function normally.

 

References

Camilleri, Michael. “Leaky Gut: Mechanisms, Measurement and Clinical Implications in Humans.” Gut, U.S. National Library of Medicine, Aug. 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6790068/.

Carrera-Bastos, Pedro, et al. “Serum Zonulin and Endotoxin Levels in Exceptional Longevity versus Precocious Myocardial Infarction.” Aging and Disease, JKL International LLC, 1 Apr. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC5963352/.

Cummins, Philip M. “Occludin: One Protein, Many Forms.” Molecular and Cellular Biology, American Society for Microbiology, Jan. 2012, www.ncbi.nlm.nih.gov/pmc/articles/PMC3255790/.

Fasano, Alessio. “Zonulin, Regulation of Tight Junctions, and Autoimmune Diseases.” Annals of the New York Academy of Sciences, U.S. National Library of Medicine, July 2012, www.ncbi.nlm.nih.gov/pmc/articles/PMC3384703/.

Forkosh, Esther, and Yaron Ilan. “The Heart-Gut Axis: New Target for Atherosclerosis and Congestive Heart Failure Therapy.” Open Heart, BMJ Publishing Group, 23 Apr. 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6519415/.

Mohammad, Shireen, and Christoph Thiemermann. “Role of Metabolic Endotoxemia in Systemic Inflammation and Potential Interventions.” Frontiers, Frontiers, 1 Jan. 2021, www.frontiersin.org/articles/10.3389/fimmu.2020.594150/full.

Novakovic, Marko, et al. “Role of Gut Microbiota in Cardiovascular Diseases.” World Journal of Cardiology, Baishideng Publishing Group Inc, 26 Apr. 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7215967/.

Pastori, Daniele, et al. “Gut-Derived Serum Lipopolysaccharide Is Associated with Enhanced Risk of Major Adverse Cardiovascular Events in Atrial Fibrillation: Effect of Adherence to Mediterranean Diet.” Journal of the American Heart Association, John Wiley and Sons Inc., 5 June 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5669181/.

Tang, W H Wilson, et al. “Gut Microbiota in Cardiovascular Health and Disease.” Circulation Research, U.S. National Library of Medicine, 31 Mar. 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5390330/.

Zhang, Li-Zi, and Sun Lei. “Changes of Junctions of Endothelial Cells in Coronary Sclerosis: A Review.” Chronic Diseases and Translational Medicine, KeAi Publishing, 8 June 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC5643598/.

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STOP SUFFERING! We specialize in advanced non-surgical approaches in treating sciatica. Our focus is to stop the pain, remove the cause and prevent chronic recurrence of complex sciatica pain syndromes. We treat with advanced protocols and supportive care plans. Blessings - Dr. Alex Jimenez DC, MSACP, IFMCP, CIFM, ATN
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