The central nervous system is home to the brain and spinal cord and its primary function are to send out neuron signals all throughout the body and make sure that the body is functioning properly. The neuron signals make sure that the body is feeling sensations whenever a person is touching something whether it be a pleasant experience or a painful experience or making sure the heart is beating regularly and the gut is properly digesting whatever it’s consuming. When there are unwanted pathogens that start to disrupt the neuron signals from traveling throughout the body and back to the brain, it can cause neurodegenerative disorders to come up in the brain and if it is not treated can lead to chronic disorders over time. There are ways to dampen the progression of neurodegenerative disorders as many individuals find ways to make small changes to their lifestyle by eating healthier food, exercising regularly, and even finding ways to relieve stress from their bodies. One of the ways to dampen neurodegenerative disorders is the usage of CBD and in this article, we will be taking a look at what the endocannabinoid system is, its functions, as well as, how CBD affects the brain and its neurological benefits. By referring patients to qualified and skilled providers who specialized in neurological services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer
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What Is The Endocannabinoid System?
The brain’s main function is to transmit neuron signals all throughout the entire body. The endocannabinoid system does the same thing in the body but does it a bit differently. Research studies have shown that the endocannabinoid system actually helps regulate and controls the most critical bodily functions of the entire body. The endocannabinoid system is a vast, densely packed network of chemical signals and cell receptors that travel throughout the brain and body like neuron signals. Other studies have shown that the endocannabinoid system is a widespread neuromodulatory system that does play many important roles in the central nervous system development, synaptic plasticity, and endogenous response in the body.
The Functions Of The Endocannabinoid System
With the endocannabinoid system, the critical physiologic system is involved in establishing and maintaining human health and homeostasis for the body and the neurotransmitters. Some of the functions that the endocannabinoid system can affect lifestyle factors include diet, sleep, psychosocial stress, relationships, body weight/ composition, and physical activity/ exercise. All of this is known as the endocannabinoid tone and the endocannabinoid tone is a function of the location density of cannabinoid receptors and shows the relative abundance or uptake of endocannabinoids that are being transmitted throughout the entire body.
HCTP (human cellular tissue products) or stem cells* are used in regenerative cellular treatment to help the body’s own natural healing process by giving it a miniature boost. In both international and nationally affiliated clinics and distribution organizations use HTCP to regenerate damaged cells, tissues, and organs back to their original function in the body and state. With more and upcoming research looking at the beneficial properties of HCTP, many individuals can begin to recover faster and be pain-free.
CBD & The Brain
With the usage of CBD and how it affects the brain, studies have found that neuroreceptors CB1 and CB2 from CBD are outside of the central nervous system and are associated with the immune system. Some of the physiologic mechanisms & benefits of CBD are:
- Anti‐inflammation – Decreased Cytokine and Chemokine action
- Analgesic Effects
- Anti‐nausea, Anti‐emetic & GI Benefits
- Reduces neural excitability and pain
Other studies have found that the acute effects of CBD can help enhance the frontostriatal brain function during a resting state and can even improve cognitive brain function in the body.
The Neurological Benefits Of Using CBD
With the neuronal protection from excitotoxicity, hypoxia, and glucose deprivation; in vivo, the neurological benefits that cannabinoids does is that they decrease hippocampal neuronal loss and
infarct volume after cerebral ischemia, acute brain trauma, and induced excitotoxicity. With these effects, it can help inhibition of glutamate transmission, reduce both the calcium influx and microglial activation in both the body and the brain. CBD can also inhibit the noxious cascades, such as tumor necrosis factor‐alpha generation and oxidative stress. Research studies also found that some of the neurological benefits that CBD offers include reducing inflammation, interacting with neurotransmitters, alleviating mental health disorders like anxiety and depression, and finally providing beneficial properties for individuals that are dealing with neurological disorders. Other neurological benefits include:
- CBD/AEA reduces Microglia inflammatory response
- Enhance Anti‐oxidant and Neuroprotection
- Improve Plasticity and BDNF
- Preserves cerebral circulation
- Reduce Pro‐inflammatory Cytokines
- Phytocannabinoids can prevent tau hyperphosphorylation in cultured neurons
All in all, the central nervous system consists of the brain and spinal cord and their job is to make sure that the neuron signals are being transmitted all throughout the body and sending the information back and forth to the brain and back. When there are unwanted factors that disrupt the neuron signals, it can lead to neurological disorders over time and cause havoc in the body. By using CBD sparingly, the individual can feel relaxed and be pain-free without the neurological disorders crippling them and disrupting their way of life.
Alger, Bradley E. “Getting High on the Endocannabinoid System.” Cerebrum: the Dana Forum on Brain Science, The Dana Foundation, 1 Nov. 2013, www.ncbi.nlm.nih.gov/pmc/articles/PMC3997295/.
Batalla, Albert, et al. “The Impact of Cannabidiol on Human Brain Function: A Systematic Review.” Frontiers in Pharmacology, Frontiers Media S.A., 21 Jan. 2021, www.ncbi.nlm.nih.gov/pmc/articles/PMC7858248/.
Grinspoon, Peter. “The Endocannabinoid System: Essential and Mysterious.” Harvard Health, 11 Aug. 2021, www.health.harvard.edu/blog/the-endocannabinoid-system-essential-and-mysterious-202108112569.
Kubala, Jillian. “6 Benefits and Uses of CBD Oil (Plus Side Effects).” Healthline, Healthline Media, 26 Nov. 2021, www.healthline.com/nutrition/cbd-oil-benefits.
Lu, Hui-Chen, and Ken Mackie. “An Introduction to the Endogenous Cannabinoid System.” Biological Psychiatry, U.S. National Library of Medicine, 1 Apr. 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC4789136.
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The information herein on "Neurological Uses for CBD" is not intended to replace a one-on-one relationship with a qualified health care professional, or licensed physician, and is not medical advice. We encourage you to make your own healthcare decisions based on your research and partnership with a qualified healthcare professional.
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Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, ATN*
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Dr. Alex Jimenez DC, MSACP, CIFM*, IFMCP*, ATN*, CCST
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