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A Look Into Virus-Mediated Neurocognitive Disorders

By
Dr. Alex Jimenez
-

Introduction

The brain’s main function in the central nervous system is to send out neuron signals from the brain and to the entire body. These signals send out information to the body and the major organs systems to not only function properly but also make sure that they’re doing their jobs. When there are unwanted factors that enter the body and start to disrupt and affect the neuron signals, it can cause the development of neurodegenerative disorders. When this happens, not only does the brain gets dysfunctional, but the gut, musculoskeletal, joints, and endocrine system start to become dysfunctional as well. In this article, we will be taking a look at what are neurodegenerative disorders and why do viruses induce cognitive function in the brain. By referring patients to qualified and skilled providers who specialized in neurological services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

What Are Neurodegenerative Disorders?

So the central nervous system consists of the brain and spinal cord and the brain’s primary job is to send out signals throughout the body to make sure it’s functioning properly. When there are unwanted pathogens that start to affect the brain and disrupt the neuron signals, that is called neurodegenerative disorders. Studies have found that cognitive functioning from the brain can be due to age and even though normal aging in the brain can help with the development of compensatory strategies, while neurodegenerative dementias can accelerate the neuropathological process thus damaging the brain. Other research studies have also shown that neurodegenerative disorders can be the result of Lewy body disease, frontotemporal degeneration, traumatic brain injury, cerebrovascular disease, and even from the effects of Alzheimer’s disease can affect cognitive function.

 

Virus-Mediated Neurodegenerative Disorders

Virus-mediated degenerative disorders can occur to the brain as any disruptors, pollutants, and air-bourne viruses can make their way inside the body. These disorders can affect the neuron signals that are traveling throughout the body and cause chronic issues to develop inside the body. Research studies have found that cognitive deficits can develop due to brain damage or neuron toxicity from these disruptors like metabolic disorders or heavy metals that can damage the neuronal tissue in the brain. One of the virus-mediated disorders that can affect the brain is the flavivirus.

 

Flavivirus & The Brain

 

Flavivirus, as research studies have shown, is emerging re-emerging arthropod-borne pathogens that are transmitted by mosquitos and ticks. Surprisingly many of the flaviviruses pathogens are neuroinvasive and neurovirulent and they can cause damage to the central nervous system. Studies have also found that when the flavivirus pathogens start damaging the central nervous system, it can cause a wide spectrum of symptoms like hemorrhagic fever and neurologic involvement causing brain bleeding. Other symptoms that flavivirus can also cause in the body is that when it crosses the epithelial and endothelial barriers of the gut, it can disrupt the tight junction and even increase the blood-brain barrier permeability as studies show.

 

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

As a form of regenerative medicine, stem cells* or HCTP (human cellular tissue products) have been used both internationally and nationally affiliated clinics and distribution organizations for individuals that are suffering from chronic illnesses. As a part of regenerative treatments, HCTP therapy has been used to help boost the body’s own natural healing process by repairing and regenerating damaged tissues, diseased organs, and cellular structures back to their original state. With more and upcoming research on the beneficial properties of HCTP and its uses, individuals can begin their wellness journey and be pain-free.

Why Do Viruses Induce Cognitive Dysfunction?

 

When viruses entered the body, the immune system will send out white cells to where the virus is attacking the body and gets rid of it. However, research studies show that when viruses start to attack the body’s immune system it can also affect the central nervous system as well. When this happens, either by directly or indirectly by viral infections, it can cause interference with the pathways of neurodegenerative diseases causing neuronal degeneration in the brain. When this happens the body can start to develop chronic inflammation and can further develop cognitive dysfunction. Other studies have shown that viral-induced cellular activity from HIV starts to release chemokine and cytokines to disrupt the blood-brain barrier and increase the number of inflammatory lymphocytes in the brain. Some of the symptoms that these viral pathogens can cause are an impact on brain structure and can cognitively impair individuals.

 

Conclusion

All in all, the brain’s primary function in the central nervous system is sending out neuron signals throughout the entire body and having a bidirectional connection with the organ systems and the body itself. When there are unwanted pathogens from either environmental disruptors or viral infections that enter the body and start to attack and disrupt the neuron signals, it can lead to cognitive dysfunction. When there is cognitive dysfunction happening in the brain, it can develop over time to neurodegenerative diseases if it is not treated. By incorporating nutritional foods that can help promote brain health and provide nutrients to the body can stop neurodegenerative diseases from progressing further in the body.

 

References

Dhakal, Aayush, and Bradford D Bobrin. “Cognitive Deficits.” StatPearls [Internet]., U.S. National Library of Medicine, 23 Nov. 2021, www.ncbi.nlm.nih.gov/books/NBK559052/.

Estofolete, Cássia F, et al. “Flavivirus Infection Associated with Cerebrovascular Events.” Viruses, MDPI, 22 June 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7354470/.

Gendelman, Howard E. “Predictive Biomarkers for Cognitive Decline during Progressive HIV Infection.” EBioMedicine, Elsevier, 14 Nov. 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC7000313/.

Karim, Sajjad, et al. “The Role of Viruses in Neurodegenerative and Neurobehavioral Diseases.” CNS & Neurological Disorders Drug Targets, U.S. National Library of Medicine, 2014, pubmed.ncbi.nlm.nih.gov/25230220/.

Laureti, Mathilde, et al. “Flavivirus Receptors: Diversity, Identity, and Cell Entry.” Frontiers in Immunology, Frontiers Media S.A., 26 Sept. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6168832/.

McDonald, William M. “Overview of Neurocognitive Disorders.” Focus (American Psychiatric Publishing), American Psychiatric Association, Jan. 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC6519631/.

Neal, J W. “Flaviviruses Are Neurotropic, but How Do They Invade the CNS?” The Journal of Infection, U.S. National Library of Medicine, Sept. 2014, pubmed.ncbi.nlm.nih.gov/24880028/.

Sachdev, Perminder S, et al. “Classifying Neurocognitive Disorders: The DSM-5 Approach.” Nature Reviews. Neurology, U.S. National Library of Medicine, 30 Sept. 2014, pubmed.ncbi.nlm.nih.gov/25266297/.

Disclaimer

Healthy Sleep, Physical Activity, and Muscle Recovery

By
Dr. Alex Jimenez
-
Young beautiful happy woman sleeping and smiles in her sleep in bed

Healthy sleep plays a vital role in the body’s overall health, as it ensures muscle growth, recovery, and illness prevention. This is especially true for home D.I. Yers’ fitness enthusiasts, weekend warriors, athletes, and physically active individuals. When sleeping, the body goes into recovery mode, releasing hormones and other chemicals to repair and restore muscle. A healthy night’s sleep provides the rest the mind and body need to perform at optimal levels.

Healthy Sleep, Physical Activity, and Muscle Recovery

Healthy Sleep

Sleep is vital for recovering from workouts. This could be construction work, exercise, gardening, sports, landscaping, any activity that uses bodyweight or works against some form of resistance. The muscles cannot repair themselves properly without proper sleep. Sleep aids the muscles in releasing protein-building amino acids, helping them grow in size and strength.

  • Growth hormone is released during non-REM sleep that stimulates tissue growth and repairs muscle.
  • During REM or rapid eye movement sleep, blood pressure drops, breathing slows and deepens, the brain relaxes, and blood supply to the muscles increases, feeding them oxygen and nutrients.

Unhealthy Sleep

Sleep maintains the muscles’ sharpness, coordination, function, and muscle movement patterns that improve physical performance. The body needs to sleep for at least 7 hours a night for muscles to grow properly. Not getting healthy sleep decreases protein synthesis activity and increases the activity of degradation that leads to muscle loss.

Less Sleep Leads To Eating More

Hormonal changes occur when the body sleeps less, causing individuals to feel hungry more often, increasing the amount of food taken in because after eating, the body does not feel full right away, so the individual continues to eat. Without sleep, the body decreases the production of a hormone that indicates when the body is full and activates a hormone that causes hunger. Insufficient sleep also lowers the body’s sensitivity to insulin. Because of this, the muscle fuel glycogen is not adequately replenished. Without the regular restoration of glycogen, individuals have less energy, insulin sensitivity decreases, increasing the risk of diabetes.

Physical Health

Unhealthy sleep also impacts overall physical health. Individuals that do not get healthy sleep have an increased risk of developing:

  • Irritability
  • Anxiety
  • High blood pressure
  • Obesity
  • Kidney disease
  • Heart disease
  • Stroke
  • Mental health issues
  • Depression

Body Composition

Nutrition Before Bed

Nighttime Snacks

  • Research has found that certain foods that contain tryptophan or melatonin can help with sleep.
  • These include turkey, bananas, milk, rice, grapefruit, oats, cherries, walnuts, and almonds.

Cut Back on Carbohydrates Before Bed

  • Consuming carbohydrate-rich foods before bed can impair growth hormone activation during sleep.

Reduce or Remove Afternoon and Evening Caffeine

  • Caffeine can impair sleep, sometimes without knowing it.
  • Avoid caffeinated foods or beverages before bed.

Eliminate Energy Drinks

  • These drinks can contain elevated levels of caffeine and other substances that can result in overstimulation.
  • This hyper-active state can cause individuals to decline in performance.
  • Overconsumption of energy drinks has been linked to adverse effects, including strokes, seizures, and death.

Eliminate Sugar

  • Sugar raises blood sugar, which triggers the pancreas to release insulin, fueling the cells causing overstimulation.
  • Eliminating sugar after dinner can help the body fall asleep.
References

Dattilo, M et al. “Sleep and muscle recovery: endocrinological and molecular basis for a new and promising hypothesis.” Medical hypotheses vol. 77,2 (2011): 220-2. doi:10.1016/j.mehy.2011.04.017

Morselli, Lisa et al. “Role of sleep duration in the regulation of glucose metabolism and appetite.” Best practice & research. Clinical endocrinology & metabolism vol. 24,5 (2010): 687-702. doi:10.1016/j.beem.2010.07.005

Murray, Bob, and Christine Rosenbloom. “Fundamentals of glycogen metabolism for coaches and athletes.” Nutrition reviews vol. 76,4 (2018): 243-259. doi:10.1093/nutrit/nuy001

Treatments For Chronic Neuro-Metabolic Syndrome | Part 2

By
Dr. Alex Jimenez
-

Introduction

When the body has an underlying condition that can change how a person looks, this is due to unwanted factors are in the body and starting to cause chaos in the body that can develop into chronic conditions. When these conditions start to affect the gut, the brain, the musculoskeletal systems, this can lead to a cluster of conditions known as chronic metabolic syndrome. In this 2 part series, we will be taking a look at what different kinds of treatments can not only dampen the effects of chronic metabolic syndrome but also improve brain health. Part 1 took a look at what chronic metabolic syndrome is and how its symptoms can affect the brain. By referring patients to qualified and skilled providers who specialized in neurological services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

Metabolic Syndrome

So metabolic syndrome, as research shows, is a cluster of conditions that can develop over time in the body. Some of the conditions that can cause the development of metabolic syndrome can include high blood pressure, increased blood glucose levels, excess body fat around the waist, and abnormal triglycerides. Other factors that metabolic syndrome can cause the body to develop apple and pear-shaped bodies for both males and females over time. Other research studies show that people with metabolic syndrome can have it increased with age and can cause neurodegenerative disorders in the brain.

 

How Does It Affect The Brain?

Since metabolic syndrome is a cluster of conditions that can cause the body to develop chronic illnesses over time, it is important to know that it can affect the brain as well. The brain is part of the central nervous system and it sends out signals all throughout the body and vice versa. These neuron signals help send out information from the brain to the entire body by making sure that it stays functional. When chronic conditions like metabolic syndrome start to disrupt and affect the signals from the brain. Studies have found that metabolic syndrome can play a significant role in the progression of Alzheimer’s disease and other neurodegenerative diseases that can affect the brain. This is due to neuroinflammation and it can cause the inflammatory cytokines to cause damage to certain parts of the brain.

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

HCTP (human cellular tissue products) or stem cells* treatment has been used in both international and nationally affiliated clinics and distribution organizations for individuals that are dealing with chronic issues. HCTP therapy is part of regenerative medicine treatment since HCTP can help boost the body’s own natural healing process by regenerating damaged cells, diseased tissues, and organs back to their original state and helping the individual be pain-free. With more upcoming research on the beneficial properties of HCTP, individuals can start their wellness journey without chronic pain.

Treatments To Improve Brain Health

The brain’s main job is to make sure that the body is functioning properly and that it’s sending out neuron signals all throughout the body in a bidirectional connection. When there are unwanted pathogens that enter the body and start to disrupt those signals from reach to the brain, it can cause neurodegenerative disorders to develop. By making small changes in a certain lifestyle that a person is used to can actually help not only improve their body but also can improve their brain health. These changes can be a variety of things that can help improve the brain like:

  • Eating nutritional foods
  • Exercising (both mentally and physically)
  • Taking supplements to improve brain health

 

Nutritional Foods

 

Since the immune system relies on white blood cells that produce antibodies to combat bacteria, viruses, and other invaders, studies have found that eating nutritious foods that are beneficial to the brain are the same ones that actually help protect the cardiovascular system. As part of the central nervous system, the brain needs certain nutritional foods to stay healthy and keep the body from dysfunction. Research studies have found that in order for the brain to function the entire body, it needs omega-3 fatty acids and antioxidants to dampen the effects of inflammation and cellular stress from progressing in the brain while also helping with building and repairing the brain cells. Not only that but a plant-based diet has also been shown to reduce inflammatory biomarkers, but eating food that contains fiber can also lower BMI, which is linked to improved immunity.

 

Exercise

 

Research studies have found that by changing a lifestyle through exercising can actually reduce age-related cognitive decline and neurodegeneration. By maintaining a healthy weight can also benefit the immune system while also providing behavioral benefits to the brain as well. Other studies have also found that aerobic fitness can actually enhance the brain’s cognitive strategies to respond effectively to any challenges a person might face with when dealing certain situations. By making sure that the brain gets a workout either intellectually or physically can provide beneficial effects to the brain and the body.

 

Supplements

 

As stated previously, foods that contain omega-3 fatty acids and antioxidants are essential for optimal brain health. For omega-3 fatty acids, studies have found that the effects of EPA, DPA, and DHA from omega-3s can dampen the effects of a variety of neurodegenerative and neurological disorders while optimizing brain health. For antioxidants, research studies have found that when oxidative stress enters the brain capacity and starts to rise up it can cause neurodegenerative disorders and cause neuronal cell death in the brain. By consuming antioxidants either through food or supplemental form can dampen the effects of oxidative stress from the brain and provide neuroprotection.

 

Conclusion

All in all, by utilizing these small changes in the body, a person can begin to feel much better with the right type of foods and supplements that can optimize their brain health. Even doing puzzles or physical exercising can help provide neuroprotection to the brain from harmful pathogens. When an individual starts taking care of their body and their brain health, it can help relieve chronic illnesses that they might not realize that they have, while also feeling good about themselves.

 

References

Arshad, Nurul `Ain, et al. “Metabolic Syndrome and Its Effect on the Brain: Possible Mechanism.” CNS & Neurological Disorders Drug Targets, U.S. National Library of Medicine, 2018, pubmed.ncbi.nlm.nih.gov/30047340/.

Baek, Seung-Soo. “Role of Exercise on the Brain.” Journal of Exercise Rehabilitation, Korean Society of Exercise Rehabilitation, 31 Oct. 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC5091051/.

Burgess, Lana. “12 Best Brain Foods: Memory, Concentration, and Brain Health.” Medical News Today, MediLexicon International, 2 Jan. 2020, www.medicalnewstoday.com/articles/324044.

Dyall, Simon C. “Long-Chain Omega-3 Fatty Acids and the Brain: A Review of the Independent and Shared Effects of EPA, DPA, and DHA.” Frontiers in Aging Neuroscience, Frontiers Media S.A., 21 Apr. 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4404917/.

Gomez-Pinilla, Fernando, and Charles Hillman. “The Influence of Exercise on Cognitive Abilities.” Comprehensive Physiology, U.S. National Library of Medicine, Jan. 2013, www.ncbi.nlm.nih.gov/pmc/articles/PMC3951958/.

Lee, Kyung Hee, et al. “Neuroprotective Effect of Antioxidants in the Brain.” International Journal of Molecular Sciences, MDPI, 28 Sept. 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7582347/.

Medical Professionals, Cleveland Clinic. “Metabolic Syndrome: Causes, Symptoms, Diagnosis & Treatment.” Cleveland Clinic, 13 Apr. 2019, my.clevelandclinic.org/health/diseases/10783-metabolic-syndrome.

Publishing, Harvard Health. “Foods Linked to Better Brainpower.” Harvard Health, 6 Mar. 2021, www.health.harvard.edu/healthbeat/foods-linked-to-better-brainpower.

Staff, Mayo Clinic. “Metabolic Syndrome.” Mayo Clinic, Mayo Foundation for Medical Education and Research, 6 May 2021, www.mayoclinic.org/diseases-conditions/metabolic-syndrome/symptoms-causes/syc-20351916.

Disclaimer

A Look Into Chronic Metabolic Syndrome Symptoms | Part 1

By
Dr. Alex Jimenez
-

Introduction

The body has many jobs to make sure that unwanted pathogens don’t enter and cause chronic issues to develop over time. With the organ systems, their jobs are to make sure that everything is functioning properly and that everything is working as well. With the central nervous system being the one to control everything, from emotions to movement, it makes sure that the neuron signals are reaching each organ and vice versa in a bidirectional connection. In this 2 part series, we will be taking a look at what is chronic metabolic syndrome and how the symptoms affect the brain. Part 2 will be discussing on what kind of treatments not only dampen the effects of metabolic syndrome but also improve brain health. By referring patients to qualified and skilled providers who specialized in neurological services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

What Is Metabolic Syndrome?

 

So metabolic syndrome, as research has stated, is a cluster of conditions that is increasingly common for many individuals. Some of the symptoms of metabolic syndrome don’t always have obvious signs that are visible, unlike a larger waist circumference. Many times metabolic syndrome can come from many factors like:

Other research studies have found that metabolic syndrome if it is not treated, can actually feed into many chronic diseases to spread like type 2 diabetes, cardiovascular diseases, oxidative stress, and even inflammation. Metabolic syndrome can also affect brain health as studies have found, that when there is systemic inflammation can actually interfere with the neuronal and glial-wellbeing of the blood-brain barrier, thus breaking the balance of the brain homeostasis. When this happens, it causes the neuron signals to disrupt the cognitive and behavioral patterns in the brain and can become permanent as well as lead to the pathway of neurodegeneration.

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

Stem cells * or HCTP (human cellular tissue products) are a form of regenerative medicine that helps boost the body’s own natural healing process by regenerating damaged cells, diseased organs, and tissues back to their original state. HCTP has also been used in regenerative treatments in both international and nationally affiliated clinics and distribution organizations to help individuals that are dealing with chronic pain and with more upcoming research discussing the beneficial properties of HCTP and how it can help many individuals become pain-free.

Chronic Metabolic Syndrome Symptoms

If an individual has metabolic syndrome, some of the tell-tale signs that they may have include a larger waistline, high blood pressure, higher triglyceride levels, and many more that can affect the body. Research shows that the combination of genetics and lifestyle factors is due to the result of insulin resistance in the body causing metabolic syndrome. When insulin resistance starts to become chronic in the body, it can turn into chronic metabolic syndrome. Chronic metabolic syndrome is developed when a person continues to do the same things in their daily routine but doesn’t make the necessary changes to better their life. Some of the symptoms that are caused due to chronic metabolic syndrome include:

  • Inflamed Brain
  • Lyme Disease
  • Mycotoxins

 

The Inflamed Brain

 

When there are inflammatory responses that are affecting the body, if it becomes too chronic, it can start affecting the brain. Studies have shown that neuroinflammation is an inflammatory response that is within the brain or the spinal cord. With neuroinflammation, it can actually become chronic and infect the blood-brain barrier permeability causing the brain to be inflamed. Other studies have researched that when there is a change in the peripheral and brain immunity as well as inflammation are involved with the pathophysiology of depression.

 

Lyme Disease

Research studies have shown that Lyme disease is a multi-organ animal-borne disease that is from the Borrelia species and is transferred from ticks. This disease can start affecting the skin, nervous system, musculoskeletal system, and heart in the body. Ticks that thrive in woodsy and grassy areas can actually affect the wildlife and even household dogs that go running through the tall grassy areas. When a tick starts latching onto exposed skin will transmit the disease to individuals causing them to develop a red ring-like expanding rash on the affected area and causing a huge variety of symptoms that can affect the body.

 

Lyme Disease Symptoms

Studies have shown that when a person is infected with Lyme disease, many symptoms that will occur if not treated, cause migraine lesions, palsies on the cranial nerves. If it starts to continue to spread, later on, it will cause arthritis on the larger joints, especially the knees. Other symptoms include:

 

Mycotoxins

 

Studies have found that when there is human exposure to water-damaged facilities in the area, it can cause neurologic and neuropsychiatric symptoms to the body and the brain. This is known as mycotoxins and research has shown that these microfungi particles can display overlapping toxicities to invertebrates, plants, and microorganisms. Now when mycotoxins are in the body, they can actually affect the central nervous system by shifting the brain’s metabolism and causing damage. Other research studies have found that different mycotoxins that enter the body and start to cause havoc on the brain’s metabolism can be very toxic to various parts of the brain causing neurodegenerative disorders. If it is not treated with antibiotics and being taken care of it can lead to chronic illnesses over time.

 

Conclusions

All in all, it is important to take care of not only the body but also the brain’s health. When there are unwanted pathogens and factors that can cause metabolic syndrome or neurodegenerative disorders, if it is not taken care of, can lead to chronic illnesses over time. By utilizing nutritious foods, exercising regularly, and making small changes in certain lifestyles can provide beneficial results to the individual who wants to feel better and start on their wellness journey.

 

References

Bennett, J W, and M Klich. “Mycotoxins.” Clinical Microbiology Reviews, American Society for Microbiology, July 2003, www.ncbi.nlm.nih.gov/pmc/articles/PMC164220/.

Biesiada, Grażyna, et al. “Lyme Disease: Review.” Archives of Medical Science: AMS, Termedia Publishing House, 20 Dec. 2012, www.ncbi.nlm.nih.gov/pmc/articles/PMC3542482/.

DiSabato, Damon J, et al. “Neuroinflammation: The Devil Is in the Details.” Journal of Neurochemistry, U.S. National Library of Medicine, Oct. 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC5025335/.

Empting, L D. “Neurologic and Neuropsychiatric Syndrome Features of Mold and Mycotoxin Exposure.” Toxicology and Industrial Health, U.S. National Library of Medicine, 2009, pubmed.ncbi.nlm.nih.gov/19854819/.

Medical Professionals, Cleveland Clinic. “Metabolic Syndrome: Causes, Symptoms, Diagnosis & Treatment.” Cleveland Clinic, 13 Apr. 2019, my.clevelandclinic.org/health/diseases/10783-metabolic-syndrome.

Sakamoto, Shinji, et al. “Inflamed Brain: Targeting Immune Changes and Inflammation for Treatment of Depression.” Psychiatry and Clinical Neurosciences, U.S. National Library of Medicine, Oct. 2021, pubmed.ncbi.nlm.nih.gov/34227186/.

Saklayen, Mohammad G. “The Global Epidemic of the Metabolic Syndrome.” Current Hypertension Reports, Springer US, 26 Feb. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC5866840/.

Sankowski, Roman, et al. “Systemic Inflammation and the Brain: Novel Roles of Genetic, Molecular, and Environmental Cues as Drivers of Neurodegeneration.” Frontiers in Cellular Neuroscience, Frontiers Media S.A., 2 Feb. 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4313590/.

Skar, Gwenn L., and Kari A Simonsen. “Lyme Disease.” StatPearls [Internet]., U.S. National Library of Medicine, 15 Feb. 2022, www.ncbi.nlm.nih.gov/books/NBK431066/.

Staff, Mayo Clinic. “Metabolic Syndrome.” Mayo Clinic, Mayo Foundation for Medical Education and Research, 6 May 2021, www.mayoclinic.org/diseases-conditions/metabolic-syndrome/symptoms-causes/syc-20351916.

Tessier, Lauren. “Mycotoxins & the Brain.” Naturopathic Doctor News and Review, Naturopathic Doctor News and Review, 4 Feb. 2021, ndnr.com/neurology/mycotoxins-the-brain/.

Disclaimer

Delayed Injury Symptoms

By
Dr. Alex Jimenez
-
Office syndrome treatment. Professional middle-aged female neurologist doctor examining neck and shoulder of young upset african woman patient during visit in medical clinic. Osteopathy concept

Automobile accidents and crashes can cause all kinds of damage to the body even when the accident/crash is not severe. Physical symptoms might not present at all for several days, even weeks. This is known as having delayed injury symptoms. These can include:

  • Swelling.
  • Stiffness.
  • Aching.
  • Pain that radiates all over the body.
  • Sleep problems.
  • Headaches.
  • Brain fog.
  • Disorientation.
  • Memory problems.

Chiropractic and physical therapy rehabilitation can restore the body’s alignment, stop inflammation, loosen, stretch and strengthen the musculoskeletal system restoring optimal health.

Delayed Injury Symptoms

Adrenaline

When the body is involved in a dangerous physical situation, it protects itself by releasing a surge of adrenaline. This hormone protects the body, causing the fight or flight response when in danger. Adrenaline causes several preservation responses that include:

  • Intense increase in energy.
  • Little or no pain.
  • Enlarged blood vessels and airways increase oxygen flow.
  • Increased strength from increased blood flow to the muscles.
  • Changes in vision and hearing that focus on sights and sounds all around.
  • Endorphins are released that make the body feel calm and in control.
  • Endorphins affect the way the body responds to pain and stress.

Individuals don’t start feeling aches and pains until the adrenaline and endorphins wear off. However, because everybody is different and the emergency response has turned off, the body still might not feel the injury symptoms. These are delayed injury symptoms.

Rate of Speed

When riding in a vehicle, the body moves at the same speed as the vehicle. During an impact, the vehicle stops, but the body continues moving until it stops, typically with a lot of force from the seatbelt, airbag, or other barriers. The intense momentum change can cause soft tissue damage and ligament or muscle strains from the stretching, pulling, contracting, and tearing. Also, the intervertebral discs can tear, bulge, or herniate over time, creating pressure on nerves and the surrounding tissues.

Delayed Injury Symptoms

Headaches

  • Headaches that develop days after an accident/crash are common.
  • They can signal a possible injury to the neck or head, a blood clot on the brain, or a concussion.

Numbness

  • Loss of feeling in arms and hands could indicate a whiplash-associated disorder.
  • The loss of feeling/sensation results from damage to the neck or spinal column.
  • Around 20 percent of individuals impacted by a rear-end crash develop some whiplash symptoms.

Neck or Shoulder Pain and/or Stiffness

  • Whiplash is a classic delayed symptom injury associated with accidents.
  • Most delayed whiplash injuries are caused by rear-end vehicle collisions at speeds of less than 14 miles an hour.
  • Whiplash injuries usually require x-rays, CT scans, or MRIs for proper diagnosis.

Abdominal Pain or Swelling

  • This could indicate internal bleeding.
  • Internal bleeding can remain undiscovered for hours or days.
  • This can be a life-threatening condition that needs to be diagnosed and treated by emergency medical personnel.
  • Other symptoms include:
  • Large areas of deep bruising.
  • Dizziness.
  • Fainting.

Back Aches and Pains

  • Back pain can be caused by injury to the muscles, ligaments, nerves, or damage to the vertebrae.
  • Low back pain occurs in more than half of rear-impact collisions and almost three-quarters of side-impact crashes.

Chiropractic Rehabilitation

After an accident, soft tissues can sustain minimal damage; however, the minimal damage left untreated can start to worsen and turn into a painful condition. Emergency room visits are to rule out major injuries like brain/nerve injuries, bleeding, punctures, lacerated organs, fractures that require emergency stabilization. Chiropractors look for other symptoms and mechanisms that indicate damage to the body’s soft tissues and nerves to see if they have been stretched or torn and dysfunction in the nervous system.

Body Composition

Calorie Counting

Counting calories can be a stepping stone to change behavior towards food. Tracking what foods are being taken into the body promotes mindfulness of dietary habits. Studies on the subject reveal a significant association between self-monitoring and weight loss. Takeaways include:

References

Burke, Lora E et al. “Self-monitoring in weight loss: a systematic review of the literature.” Journal of the American Dietetic Association vol. 111,1 (2011): 92-102. doi:10.1016/j.jada.2010.10.008

D’Elia, Michael A et al. “Motor vehicle collision with seatbelt sign and traumatic abdominal wall hernia should raise suspicion for hollow viscus injury.” Trauma case reports vol. 22 100206. 25 May. 2019, doi:10.1016/j.tcr.2019.100206

Kacprzynski, Gregory, and Joshua Bucher. “Delayed vertebral artery dissection after mild trauma in a motor vehicle collision.” The American Journal of emergency medicine vol. 45 (2021): 678.e1-678.e2. doi:10.1016/j.ajem.2020.11.028

Olinger, Catherine, and Richard Bransford. “Upper Cervical Trauma.” The Orthopedic clinics of North America vol. 52,4 (2021): 451-479. doi:10.1016/j.ocl.2021.05.013

Sterling, Michele. “Whiplash-associated disorder: musculoskeletal pain and related clinical findings.” The Journal of manual & manipulative therapy vol. 19,4 (2011): 194-200. doi:10.1179/106698111X13129729551949

Factors That Can Affect The Brain | Part 2

By
Dr. Alex Jimenez
-

Introduction

The brain’s main function in the central nervous system is to send out neuron signals all throughout the body. What this does is that these signals go from the brain through the spinal cord and send out the information for the body to function and vice versa. These signals make sure that the organ system is doing its job properly and making the body move as well. When there are unwanted pathogens entering the body, it can disrupt the neuron signals from reaching the brain and cause chronic symptoms that can develop over time causing the person pain. In this 2 part series, we will be taking a look at how cortisol and inflammation affect the brain as well as how the gut and the brain make a connection. Part 1 discussed what is the central nervous system and what factors can affect the brain. By referring patients to qualified and skilled providers who specialized in neurological services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

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The Central Nervous System

The central nervous system is consist of the brain and the spinal cord in the body. What this system does, as research shows, is that it signals all the neurons in the body and transports them back and from the brain to the entire body. Each nerve signal makes sure that the entire body is moving and each organ system is getting the signals and sending them back to the brain. Some of the functions that the central nervous system does are that it controls how a person breathes, releases hormones, controls body temperature, and controls emotions as studies show. With the brain’s main function is to send out signals throughout the body, surprisingly, some of the factors can actually affect the brain signal if it becomes too chronic and they are cortisol and inflammation.

 

Cortisol & The Brain

Now cortisol is a stress hormone that gives the body a little boost of energy when an individual is dealing with a situation. Even though stress can be beneficial to the body it can also become chronic if it is not taken care of. Too much stress can lead to chronic pain and as studies have found, cortisol is released by the activation of the HPA (hypothalamic-pituitary-adrenal) axis, and when that increases can lead to age-related cognitive disorders in the brain. Other studies have found that when there is long-term elevated cortisol affecting the brain it can negatively influence cardiometabolic changes in the body. See the brain can send signals to the endocrine system to release hormones to get the body to function at normal levels, but when cortisol levels begin to rise in the body it can affect the brain.

 

 

Other studies have shown that when stress begins in the brain and starts to affect it, can cause pathophysiology changes to the neural, cardiovascular, immune, and metabolic systems in the body. The brain gives the signal of a “fight or flight” response to the body as it endures stressful situations. When the cortisol levels become chronic, the brain signals will be disruptive and cause chronic symptoms to develop over time and cause the individual pain.

 

Inflammation & The Brain

Just like cortisol, inflammation does the same thing to the body. When there are unwanted pathogens entering the body and causing havoc, the immune systems send out inflammatory cells to the affected area and attack the pathogen. Studies have found that inflammatory cytokines are produced by the nervous system to produce behavioral symptoms and characteristics of the illness to stop the infection from spreading and healing the body.

 

However, if the inflammatory cells start to attack the body out of nowhere and there are no unwanted pathogens attacking the body, then it can become chronic. Studies have found that chronic inflammation can increase the peptides and age can become the risk factor for Alzheimer’s disease while also becoming a role in the development of neurodegeneration.

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

HCTP (human cellular tissue products) or stem cells* have been used in regenerative therapy treatments in both international and nationally affiliated clinics and distribution organizations to help individuals with chronic pain. HCTP has been used to help boost up the body’s own natural healing process by regenerating and repairing damaged tissues, diseased organs, and cellular structure back to their original state in the body. With more upcoming research discussing about the beneficial properties of HCTP, it can help the individual be pain-free and let them continue their wellness journey.

The Gut-Brain Connection

 

Research studies have found that the gut and brain are connected to each other as they send a bidirectional connection to each other and promote the proper maintenance of gastrointestinal homeostasis. Other articles have talked about how the brain and gut are even more connected through the endocrine system. While the effects from the gut microbiota can help regulate the neurotransmitters from the brain and the brain’s effects on the gut can help intestinal development and barrier integrity and function as studies show. When unwanted pathogens like chronic inflammation and chronic cortisol affect both the gut and the brain, it can cause the body to be dysfunctional and can cause the individual person pain in their body.

 

Conclusion

All in all, by regulating cortisol and inflammation levels in the body can provide beneficial results to the brain signals to be functioning normally. By eating nutritious food, making small changes in a certain lifestyle, and exercising regularly can help the individual get their life together and be pain-free. Not only that but keeping a healthy brain can dampen the effects of neurodegenerative disorders from progressing even further as the body ages naturally and the brain is “young” and healthy.

 

Reference

Blasko, Imrich, et al. “How Chronic Inflammation Can Affect the Brain and Support the Development of Alzheimer’s Disease in Old Age: The Role of Microglia and Astrocytes.” Aging Cell, U.S. National Library of Medicine, Aug. 2004, pubmed.ncbi.nlm.nih.gov/15268750/.

Braniste, Viorica, et al. “The Gut Microbiota Influences Blood-Brain Barrier Permeability in Mice.” Science Translational Medicine, U.S. National Library of Medicine, 19 Nov. 2014, www.ncbi.nlm.nih.gov/pmc/articles/PMC4396848/.

Carabotti, Marilia, et al. “The Gut-Brain Axis: Interactions between Enteric Microbiota, Central and Enteric Nervous Systems.” Annals of Gastroenterology, Hellenic Society of Gastroenterology, 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4367209.

de Souza-Talarico, Juliana Nery, et al. “Effects of Stress Hormones on the Brain and Cognition: Evidence from Normal to Pathological Aging.” Dementia & Neuropsychologia, Associação De Neurologia Cognitiva e Do Comportamento, 2011, www.ncbi.nlm.nih.gov/pmc/articles/PMC5619133/.

Echouffo-Tcheugui, Justin B, et al. “Circulating Cortisol and Cognitive and Structural Brain Measures: The Framingham Heart Study.” Neurology, Lippincott Williams & Wilkins, 20 Nov. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6260201/.

Ludwig, Parker E. “Neuroanatomy, Central Nervous System (CNS).” StatPearls [Internet]., U.S. National Library of Medicine, 14 Oct. 2021, www.ncbi.nlm.nih.gov/books/NBK442010/.

McEwen, Bruce S. “Central Effects of Stress Hormones in Health and Disease: Understanding the Protective and Damaging Effects of Stress and Stress Mediators.” European Journal of Pharmacology, U.S. National Library of Medicine, 7 Apr. 2008, www.ncbi.nlm.nih.gov/pmc/articles/PMC2474765/.

Newman, Tim. “Central Nervous System: Structure, Function, and Diseases.” Medical News Today, MediLexicon International, 3 Feb. 2022, www.medicalnewstoday.com/articles/307076.

Sartori, Andrea C, et al. “The Impact of Inflammation on Cognitive Function in Older Adults: Implications for Healthcare Practice and Research.” The Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses, U.S. National Library of Medicine, Aug. 2012, www.ncbi.nlm.nih.gov/pmc/articles/PMC3390758/.

Disclaimer

The Neuroimaging Of The Brain | Part 1

By
Dr. Alex Jimenez
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Introduction

The brain’s main function is to send signals throughout the body in order for it to function properly. These signals are traveling to each of the organ systems in the body. From the gut system, the immune system, and even the endocrine system, the brain will send signals to these systems, and vice versa the organ systems will send signals back to the brain.  In this 2 part series, we will be taking a look at what is the central nervous system and what factors can affect the brain. In part 2, we will take a look at how cortisol and inflammation affect the brain as well as how the gut and the brain make a connection. By referring patients to qualified and skilled providers who specialized in neurological services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

What Is The Central Nervous System?

 

So the nervous system is where the body receives information and helps it function properly. Research shows that the nervous system is consist of two main parts of the body which are the peripheral nervous system and the central nervous system. So the peripheral nervous system has many nerves that are being branched off from the spinal cord and extend all throughout the entire body. The central nervous system is where the brain and the spinal cord are there to make sure that the body is functioning properly. The nervous system has many neurons throughout the body that has many different jobs that send out messages to the brain and can perform many different activities. Some of the different neurons can help the muscles move in the body, other neurons can help the body’s senses like hearing, taste feeling pressure on the skin and other neurons can help keep the organ systems functioning, like regulating heartbeat and hormonal release.

 

The Brain

 

The brain is the body’s main control system, where it sends out signals to the body and makes sure that it is keeping an individual alive. Consist of three main structures, research studies show that the brain will send out signals throughout the body that can help regulate different biological functions and even sense any environmental changes that can affect the body. The three structures of the brain are the cerebrum, cerebellum, and brain stem. Each of these structures makes sure that the brain is working properly and that it sends signals throughout the body to make it function properly as well. The brain is also connected to the spinal cord where some of the important functions like muscle movement, secreting hormones, and emotions are being controlled by the brain.

 

The Spinal Cord

 

As one of the main parts of the central nervous system, the spinal cord is a long structural, cylindrical tube of tissue that runs in the middle of the spine. Research shows that the spinal cord is connected to the brain, specifically the brainstem, all the way to the lower back. These tubes of tissue carry out nerve signals from the brain to the entire body and vice versa since it’s all connected to the central nervous system. When these nerve signals are going through the entire body, the spinal cord has three functions to make sure that the body is working properly. These functions include controlling body movements and functions like walking or running and even regulating heartbeat and breathing rate, helping the brain to record different sensations that a person is experiencing, and even managing involuntary reflexes. All of these are important for the spinal cord to send through the brain to make sure that the body is functioning properly.

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

Stem cells* or HCTP (human cellular tissue products) are considered a form of regenerative medicine that helps repair and regenerate damaged cells, diseased tissues, and organs back to their original state. HCTP is used as therapeutic treatment in both international and national affiliated clinics and distribution organizations for individuals that are dealing with chronic issues in their bodies. Since HCTP is used to help boost up the body’s own natural healing process, there is still more upcoming research about the beneficial properties that HCTP can do for the body and make the individual pain-free.

Factors That Can Affect The Brain

Since the brain can help the body by sending signals to each of the organ systems, it is important to take care of the brain as well. As the body starts growing and aging, so does the brain as there are many factors that can actually affect the brain. Some of the factors can be good like listening to music, exercising (both mentally and physically), sleep habits, and intellectual stimulation like puzzles. Other factors can be harmful to the brain like neurodegenerative diseases, head traumas, mood shifts, inflammation can cause unwanted problems to the brain and can disrupt the brain signal to the entire body.

 

Neurodegenerative Diseases

Studies have shown that neurodegenerative diseases are a cluster of chronic, progressive disorders that affect the neurons in the central nervous system. Some of these neurodegenerative diseases actually can affect brain function and even cause damage to the central nervous system. These include:

Other studies have shown that when there is an increase in inflammation affecting the body, it can cause many neurodegenerative diseases to progress further into chronic disorders. When the inflammatory cells start to affect the immune cells in the body, it can start triggering and amplifying the degeneration in the brain.

 

Music

Studies have found that music can have an efficient method of dealing with emotions and the autonomic nervous system. A perfect example is when a person is listening to music and the way that their emotions begin to pour out as they sing to the lyrics. When a person is singing a song, it causes them to feel much better afterward due to belting out the song and pouring their emotions as they understand what the lyrics are saying. Studies have found that listening to music can help lower the heart rate, respiration rate, and blood pressure from the body. By lowering the cortisol levels in the body can provide beneficial results to the brain and improve the mood that the brain is signaling.

 

Conclusion

All in all, there are many factors that can affect the brain’s neuron signal to the body. The central nervous system makes sure that the brain is doing its job properly and making sure the neuron signals are sending the information from the brain throughout the body and vice versa. When there are factors that are affecting the brain’s signal in the body, it can cause chronic symptoms to pop up and disrupt the signals from reaching the other systems in the body, and when this happens, it can cause a person to feel horrible. By finding the cause of the situation that is cause the person pain and dampening its effect can cause relief to the individual.

 

References

Chitnis, Tanuja, and Howard L Weiner. “CNS Inflammation and Neurodegeneration.” The Journal of Clinical Investigation, American Society for Clinical Investigation, 2 Oct. 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5617655/.

Ellis, Robert J, and Julian F Thayer. “Music and Autonomic Nervous System (Dys)Function.” Music Perception, U.S. National Library of Medicine, Apr. 2010, www.ncbi.nlm.nih.gov/pmc/articles/PMC3011183/.

Gao, Hui-Ming, and Jau-Shyong Hong. “Why Neurodegenerative Diseases Are Progressive: Uncontrolled Inflammation Drives Disease Progression.” Trends in Immunology, U.S. National Library of Medicine, Aug. 2008, www.ncbi.nlm.nih.gov/pmc/articles/PMC4794280/.

Jia, Tiantian, et al. “Music Attenuated a Decrease in Parasympathetic Nervous System Activity after Exercise.” PloS One, Public Library of Science, 3 Feb. 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC4739605/.

Martin, Lauren. “The Human Brain: Parts, Function, Diagram, and More.” Medical News Today, MediLexicon International, 4 July 2021, www.medicalnewstoday.com/articles/brain.

Medical Professional, Cleveland Clinic. “Spinal Cord: Function, Anatomy, and Structure.” Cleveland Clinic, 7 Oct. 2021, my.clevelandclinic.org/health/body/21946-spinal-cord.

Office of Communications, NIH. “What Are the Parts of the Nervous System?” Eunice Kennedy Shriver National Institute of Child Health and Human Development, U.S. Department of Health and Human Services, 1 Oct. 2018, www.nichd.nih.gov/health/topics/neuro/conditioninfo/parts.

Disclaimer

Neuromusculoskeletal Optimization

By
Dr. Alex Jimenez
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Physical therapist does manual therapy to a young athletic guy at medical office. Concept of manual therapy and osteopathy

Chiropractic is a form of neuromusculoskeletal care that repairs and re-optimizes the nervous system that helps to relieve tension, inflammation, pain and restore body health. Like any piece of machinery that requires regular maintenance to operate correctly without issues, so too is the body an exquisite machine that needs regular maintenance. Treatment restores and maintains optimal function to the nervous system, muscles, bones, tendons, ligaments, and joints.

Neuromusculoskeletal Optimization

Neuromusculoskeletal Care

Central Nervous System – CNS

  • The Central Nervous System or CNS is the body’s computer.
  • It processes functions in the body and mind.
  • It s made up of the brain and spinal cord.
  • It helps process external information through sight, sound, touch, smell, and taste.
  • The CNS interprets sensory information that goes through the spinal cord to the brain, and the body responds accordingly.
  • It controls voluntary movements like walking, talking, exercising.
  • It controls involuntary movements like blinking, breathing, digestion.
  • It allows thoughts, emotions, and perceptions to be created and expressed.

When the Central Nervous System works correctly, the body is coordinated, all senses send and receive information effectively, and cognition/thinking is clear. 

Peripheral Nervous System – PNS

  • The Peripheral Nervous System or PNS transmits signals from the outside to the Central Nervous System.
  • The PNS is comprised of all the nerve bundles that run throughout the body.
  • The PNS is responsible for transmitting information back and forth from the CNS to the rest of the body by electrical impulses and current.

When the PNS is functioning correctly, and there is thorough nerve circulation throughout the body, there are no issues like numbness, weakness, pain, and digestion is in top form.

Enteric Nervous System – ENS

  • The Enteric Nervous System or ENS is a branch of the peripheral nervous system that signals the digestive system.
  • It comprises nerves that stretch across the entire gastrointestinal tract.
  • It allows the nervous system to communicate with the digestive tract and regulate activity.
  • It can stop the digestive process when the body is under stress or strain, i.e., fight or flight response.
  • Chronic stress can create dysfunction in the digestive system.
  • Inflammation and stress can cause the enteric system to disrupt and cause digestive problems.

Pain Relief

Body pain can be an indication of an imbalance in the nervous system. Misalignment from work, home activities, trauma, injury, or posture problems, a subluxation/misalignment can turn into discomfort that leads to pain and neuromusculoskeletal system issues. Pain in the neuromusculoskeletal system can result from spinal misalignment and a shifting skeletal structure. The joints and misaligned bones compress the surrounding nerves and tissue, causing inflammation that results in pain symptoms. This causes the muscular system to compensate for the lack of stability support from the skeletal structure causing awkward body posturing. A chiropractor realigns the spinal structure, removing the compression/pressure from the nerves, tissues, muscles, ligaments, and tendons.

Body Composition

Chiropractic Medicine

The nervous system is highly responsive to chiropractic care because of chiropractic’s focus on the spine, which restores and rejuvenates. Chiropractic medicine and a properly aligned spine:

  • Reduces and eliminates pain.
  • Reduces and eliminates headaches and migraines.
  • Improves balance and coordination.
  • Improves digestive function.
  • Improves quality of sleep.
  • Increases energy.
  • Increases flexibility and mobility.
  • Enhances cognition and clear thinking.
References

Goudman, Lisa et al. “The Link Between Spinal Cord Stimulation and the Parasympathetic Nervous System in Patients With Failed Back Surgery Syndrome.” Neuromodulation: journal of the International Neuromodulation Society vol. 25,1 (2022): 128-136. doi:10.1111/ner.13400

Gyer, Giles et al. “Spinal manipulation therapy: Is it all about the brain? A current review of the neurophysiological effects of manipulation.” Journal of integrative medicine vol. 17,5 (2019): 328-337. doi:10.1016/j.joim.2019.05.004

Millet, Guillaume Y et al. “The role of the nervous system in neuromuscular fatigue induced by ultra-endurance exercise.” Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme vol. 43,11 (2018): 1151-1157. doi:10.1139/apnm-2018-0161

Stoll, T et al. “Physiotherapie bei lumbaler Diskushernie” [Physiotherapy in lumbar disc herniation ]. Therapeutische Umschau. Revue therapeutique vol. 58,8 (2001): 487-92. doi:10.1024/0040-5930.58.8.487

Personalizing Cardiovascular Medicine For The Body

By
Dr. Alex Jimenez
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Introduction

The cardiovascular system‘s main role is to make sure that blood is pumping from the heart to all over the rest of the body through the veins and arteries. The blood cells are transporting oxygen, hormones, and nutrients to each of the organ systems. From the gut to the brain to the endocrine system, they need these blood cells to do their jobs properly. When there are disruptors that can affect the body, especially the cardiovascular system it can do some serious damage by conducting cardiovascular diseases to develop over time and cause the body pain. In this article, we will be taking a look at the difference between precision and personalized medicine for cardiovascular disease, the genetics, and genomics of CVD, as well as looking at how glutathione helps reduce CVD. By referring patients to qualified and skilled providers who specialized in cardiovascular services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

What Is The Difference Between Personalized & Precision Medicine?

So personalized medicine is actually a medical model that separates people into different groups, which includes medical decisions, practices, interventions, and/or products that are being tailored to the individual patient based on their predicted response or risk of disease. Research studies showed that personalized medicine for cardiovascular disease is an emerging concept that can help manage an individual’s symptoms and even provide guidance for selecting treatments. Since cardiovascular disease still remains one of the leading causes of death, by focusing on the research and treatment, the individual is there with their healthcare provider to make the decisions. Other research studies have shown that personalized medicine treatment for cardiovascular disease is tailored to the individual with all the decisions and practices to not only treat cardiovascular disease but to figure out what is the best course of action to treatment.

 

Precision Medicine For Cardiovascular Disease

Precision Medicine is where medical care is designed to optimize efficiency or therapeutic benefit for particular groups of patients, especially by using genetic or molecular profiling. Surprisingly though, studies have stated that precision medicine has a more integrative approach to cardiovascular disease prevention and treatment by looking into the individual’s exposure to their cardiovascular health as determinants, while also finding strategies to improve cardiovascular health and preventing chronic diseases from rising in the body.

 

The Genetics Of Cardiovascular Disease

Since cardiovascular disease is a range of conditions that can cause problems to the cardiovascular system and the body, it is important to figure out the DNA sequence and the genes to cardiovascular disease. Research shows that discovering the genes for cardiovascular disease by looking at the linking analysis and the genetic association of cardiovascular disease. By correlating and identifying the specific genes as well as the DNA sequence to any chronic diseases that affect the body can give healthcare providers the results they need. Since reduction and prevention of chronic heart disease are not likely to improve without using genetic markers and gene expression testing to identify these pathways.

 

 

Since over 60% of the chronic heart disease risk, variants mediate risk independent of traditional known risk factors with unknown mechanisms or pathways. 40% overlap with genomic loci with classical risk factors. The three most frequently found loci are:

  • 9p21.3 (epigenetic gene regulation- noncoding RNA to induce CHD.
  • 6p24.1. (CHD in Chinese and Singapore and DVT)
  • 1p13.3 (affects LDL-C).

Other research studies have shown that by searching the genes that are being predisposed to cardiovascular disease, health care professionals can identify the common DNA types in human variations for cardiovascular disease and start to contribute to preventing cardiovascular diseases while providing therapeutic measures.

 

How Does The Genomics Play In Cardiovascular Disease?

Research shows that by identifying the DNA regions that have been predisposed or the cause of cardiovascular disease. By looking at the DNA sequence, it can help clinicians to detect the phenotype of cardiovascular disease. The best yield of genome-wide association studies (GWAS) the pathways that underlie causes of CVD/CHD such as inflammation, oxidative stress, and immunologic vascular dysfunction. Looking at how different pathways are being affected by cardiovascular disease in the body is useful in trying different therapeutic ways of lowering the effects of chronic illnesses that are damaging the arteries in the cardiovascular system.

 

Oxidative Stress & Cardiovascular Disease

When there is an imbalance of ROS (reactive oxygen species) in the body due to oxidative stress and cardiovascular disease, the body will deal with many chronic symptoms that can damage the cellular structure. Research studies show that when there are excess amounts of ROS in the body it can damage the DNA molecules, lipids, and proteins causing necrosis and apoptotic cell death. When this happens the body will develop chronic inflammation and endothelial dysfunction, which are contributors to cardiovascular disease.

 

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

HCTP (human cellular tissue products) or stem cells* are a form of regenerative medicine that helps boost the body’s own natural healing process. Both international and nationally affiliated clinics and distribution organizations use HCTP as therapeutic treatments for individuals that are dealing with chronic pain in their bodies. HCTP is used to help repair and regenerate damaged cells, diseased tissues, and organs back to their original state and function so individuals can be pain-free.

Glutathione & Cardiovascular Disease

 

When the body has been affected by cardiovascular disease, the complications from the cardiovascular system will cause enhanced levels of free radicals that will cause impaired redox homeostasis. Research shows that the role of glutathione can help reduce oxidative stress in the body with its antioxidant properties. The GLUL gene on chromosome 1q25 increases chronic heart disease in diabetes mellitus by reducing the expression of glutamine synthase which converts glutamic acid to glutamine. The heart needs the effects of glutathione to preserve the redox homeostasis from cardiovascular disease while also regulating oxidative stress and reductive stress in the body.

 

Conclusion

All in all, finding ways to prevent cardiovascular disease from rising in the body is highly important for anyone that wants to start on their wellness journey. Getting a routine check-up from healthcare providers, eating nutritious foods that are beneficial to the heart, exercising regularly, and taking nutraceutical supplements that help the body can provide amazing results in dampening chronic illnesses. Taking these small steps can help a person be pain-free and continue to live life to the fullest.

 

References

Abbate, Rosanna, et al. “Genetics of Cardiovascular Disease.” Clinical Cases in Mineral and Bone Metabolism: the Official Journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases, CIC Edizioni Internazionali, Jan. 2008, www.ncbi.nlm.nih.gov/pmc/articles/PMC2781194/.

Bajic, Vladan P, et al. “Glutathione ‘Redox Homeostasis’ and Its Relation to Cardiovascular Disease.” Oxidative Medicine and Cellular Longevity, Hindawi, 9 May 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6532282/.

Kathiresan, Sekar, and Deepak Srivastava. “Genetics of Human Cardiovascular Disease.” Cell, U.S. National Library of Medicine, 16 Mar. 2012, www.ncbi.nlm.nih.gov/pmc/articles/PMC3319439/.

Lee, Moo-Sik, et al. “Personalized Medicine in Cardiovascular Diseases.” Korean Circulation Journal, The Korean Society of Cardiology, Sept. 2012, www.ncbi.nlm.nih.gov/pmc/articles/PMC3467440/.

Leopold, Jane A, and Joseph Loscalzo. “Emerging Role of Precision Medicine in Cardiovascular Disease.” Circulation Research, U.S. National Library of Medicine, 27 Apr. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6021027/.

Roberts, Robert, et al. “Genomics in Cardiovascular Disease.” Journal of the American College of Cardiology, U.S. National Library of Medicine, 21 May 2013, www.ncbi.nlm.nih.gov/pmc/articles/PMC3683584/.

Senoner, Thomas, and Wolfgang Dichtl. “Oxidative Stress in Cardiovascular Diseases: Still a Therapeutic Target?” Nutrients, MDPI, 4 Sept. 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6769522/.

Tada, Hayato, et al. “Personalized Medicine for Cardiovascular Diseases.” Journal of Human Genetics, U.S. National Library of Medicine, 8 Aug. 2020, pubmed.ncbi.nlm.nih.gov/32772049/.

Disclaimer

Sacral Fracture

By
Dr. Alex Jimenez
-
X-Ray pelvis shot isolated on white

For older individuals, experiencing frequent low back pain could turn out to be a sacral fracture. They tend to occur in individuals over the age of 60 often because there has been a degree of bone loss. Sacral fractures tend not to be the first thing doctors think of when low back pain symptoms are presenting. They are often not picked up on X-rays and are either not diagnosed early enough to take steps or not diagnosed at all. However, they are common.

Sacral Fracture

Sacrum

The sacrum is shaped like a triangle and comprises five segments fused into one large bone. It sits at the base of the spine,  between the two halves of the pelvis, connecting the spine to the lower half of the body. It stabilizes the body when walking, sitting, or standing. The nerves in the lower spine control the bowels bladder and provide sensation to the region.

  • The two dimples that can be seen on individuals’ backs are where the sacrum joins the hipbones or the sacroiliac joint.
  • The point where the low back joins the sacrum can develop discomfort, soreness, and pain.
  • This area experiences stress from bending, twisting, reaching, lifting, carrying during physical activities or sitting for long periods.

Sacral Fracture

Most sacral fractures result from trauma, like slips, falls, and automobile accidents. Stress fractures that happen without a specific injury are also called insufficiency fractures.

Types of Sacral Fractures

  • Low-energy fractures usually happen to older individuals with weak bones due to osteoporosis.
  • An individual trips on something, lands hard on their butt, lifts a heavy object awkwardly, or over-exerts themselves from some physical activity.
  • Then persistent back or buttock pain begins to present.
  • The pain is often centered in the lower back, the hips, and butt.
  • It is more than just back achiness.
  • The individual goes to the doctor, and X-rays are ordered.
  • A lot of the time, these fractures are missed on X-rays.
  • The doctor may diagnose a sprain, but the pain symptoms do not improve.
  • Sometimes there is no apparent cause for the pain.
  • It can be misdiagnosed as a lower back compression fracture or urinary tract infection.

 

  • High-energy fractures are due to trauma and are more common among the young.
  • The individual sustains injuries from an auto accident, has fallen from a significant height, or suffers a sports injury.
  • It results in severe pain.
  • A woman who has just had a baby and gone through some bone loss because of the pregnancy can experience a sacral stress fracture.

Diagnosis

The most common causes for low back pain include:

  • Frequent improper posture.
  • Muscle weakness or tightness.
  • Ligament strain.
  • Joint inflammation.
  • A pilonidal cyst or an anal fissure can also cause pain.

For individuals that have been to a doctor and had an X-ray that reveals no fracture, and there is no improvement after 5 to 7 days, it is recommended to schedule another appointment and ask for a CAT scan or MRI, which is highly effective at finding a sacral fracture.

Treatment

Treatment consists of resting the bone but still being safely active in most cases.

  • Medication is prescribed for pain relief.
  • Many individuals have been found to do well with anti-inflammatory medications, topical medications, and lidocaine patches.
  • Older individuals may be recommended to use a walker during the treatment/healing process.
  • Depending on the severity, crutches may be recommended.
  • Engaging in regular exercise is not recommended, but too much bed rest is also not recommended.
  • Too much rest may not allow the injury to heal correctly, worsen the injury, and/or cause new injuries.
  • Chiropractic and physical therapy are not recommended to let the sacrum naturally heal.
  • After the pain subsides, chiropractic and physical therapy can be implemented to maintain agility and flexibility and strengthen the pelvic and core muscles.

In some cases, if the bone does not heal correctly or some other issue, sacroplasty could be recommended. This is a minimally invasive procedure that injects bone cement into the fracture. It offers quick and long-lasting pain relief with a low percentage of complications. It is considered low risk and can be done by an interventional radiologist or spine surgeon.

Prevention

To minimize the risk of a sacral fracture, it is highly recommended to maintain bone strength. This consists of:

Body Composition

Sitting Posture Adjustments

Adjust Sitting

Change Chair

  • Try a solid wooden chair if unable to use a ball or sit-stand desk.
  • It will make the body sit up straight and increase proper posture.

Move Around Alarm

References

Gibbs, Wende Nocton, and Amish Doshi. “Sacral Fractures and Sacroplasty.” Neuroimaging clinics of North America vol. 29,4 (2019): 515-527. doi:10.1016/j.nic.2019.07.003

Holmes, Michael W R, et al. “Evaluating Abdominal and Lower-Back Muscle Activity While Performing Core Exercises on a Stability Ball and a Dynamic Office Chair.” Human factors vol. 57,7 (2015): 1149-61. doi:10.1177/0018720815593184

Santolini, Emmanuele et al. “Sacral fractures: issues, challenges, solutions.” EFORT open reviews vol. 5,5 299-311. 5 May. 2020, doi:10.1302/2058-5241.5.190064

Integrative Nutraceutical Approach To Dyslipidemia | Part 2

By
Dr. Alex Jimenez
-

Introduction

In the cardiovascular system, the heart’s main purpose is to pump blood throughout the entire body and to transport nutrients, hormones, and oxygen to the necessary musculoskeletal tissues and organs that need to do their job properly. When there are pathogens that enter the body, whether it is a poor lifestyle or poor nutrition that can cause the body to develop chronic illnesses, it can cause damage to the cardiovascular system. Some of the cardiovascular disease risk factors like dyslipidemia can disrupt the body’s blood flow throughout the body. In this 2 part series, we will be taking a look at what nutraceuticals are used to dampen the effects of dyslipidemia. In part 1, we discussed what dyslipidemia is, its symptoms, and how chronic inflammatory macro-and micronutrients can affect the cardiovascular system. By referring patients to qualified and skilled providers who specialized in cardiovascular services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

What Does Dyslipidemia Do To The Body?

In part 1, dyslipidemia is where the lipid levels in the blood are either too high or too low in the bloodstream. As research shows when individuals are getting a routine blood test from their primary healthcare provider, they are unaware that they may have dyslipidemia. If it gets severe or untreated, dyslipidemia can lead to other cardiovascular diseases like coronary artery disease and peripheral artery disease.

 

Dyslipidemia Factors

Research shows that dyslipidemia is an imbalance of lipids in the body that can cause a variety of disorders that can affect the body and can be classified into five categories. When there is an imbalance of lipids in the bloodstream, it is due to many factors that can cause dyslipidemia to go unnoticed until it is severe and it leads to cardiovascular disease with severe complications. These factors can be:

 

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

Stem cells* or HCTP (human cellular tissue products) are used in regenerative cellular treatments that are located both nationally and internationally affiliated clinics and distribution organizations. HCTP‘s main job is to help boost the body’s own natural healing process while also repairing and regenerating damaged cells, tissues, and organs back to their original state in the body.

Nutraceuticals For Dyslipidemia

Surprisingly there are many ways to lower dyslipidemia and even lower cholesterol for the heart. Research shows that the role of nutraceuticals has the ability to lower LDL-C (low-density lipoprotein cholesterol) and when it is combined with a lipid-lowering diet can even lower inflammation, oxidative stress, cardiovascular diseases, and improve immune response. Some of the nutraceuticals that can help lower dyslipidemia include:

 

Red Yeast Rice

Used in traditional Chinese medicine, red yeast rice is a diet staple in Asia. Studies have found that red yeast rice has been used as an alternative to statin therapy for individuals who have mild to moderate hypercholesterolemia. Other studies have shown that red yeast rice contains lovastatin and can help lower cholesterol levels by making sure that the intestines don’t absorb the cholesterol and are secreting the cholesterol out of the body through the stool.

 

Berberine

 

Since hyperlipidemia and dyslipidemia are two of the major risk factors for cardiovascular diseases, berberine can actually dampen the effects of these two risk factors from rising in the body. Studies have found that berberine has been used in Chinese medicine and can actually treat many different conditions like type 2 diabetes and hypertension in the body. Other studies also found that berberine has a great impact on lowering total cholesterol, LDL-C, HDL, and triglycerides in the body.

 

Pomegranate

Pomegranates are filled with antioxidants that can help lower cardiovascular diseases. Since all berries and fruits that contain polyphenols help lower the risk of inflammation in the body, consuming pomegranates in juice form or by eating the fruit itself does wonder for the body. Studies have shown that concentrated pomegranate juice can help improve the lipid profiles of diabetics that have hyperlipidemia. By adding pomegranates into a heart-healthy diet can provide the necessary nutrients for the body and lower the risk of cardiovascular disease.

Research has been shown that pomegranate has a huge amount of beneficial properties that can help the body not only lower inflammation in the body with its antioxidants but with more than 100 phytochemicals that can help lower the risk of dyslipidemia from rising. Other beneficial properties that pomegranate can provide include:

 

Conclusion

By incorporating some of these nutraceuticals into a heart-healthy diet can help lower cardiovascular diseases. By making small changes to a person’s lifestyle, eating whole nutritional food, taking multi-vitamins, and exercising can provide the individual a new outlook in life and even get rid of ailments that have caused them pain. When there are unwanted pathogens that can affect the body and the organs causing chronic symptoms rise over time making the person’s life miserable. When they start making these small changes in their life they can recover their sense of fulfillment in the world pain-free.

 

References

Bertuccioli, Alexander, et al. “Berberine and Dyslipidemia: Different Applications and Biopharmaceutical Formulations without Statin-like Molecules-a Meta-Analysis.” Journal of Medicinal Food, U.S. National Library of Medicine, 23 Aug. 2019, pubmed.ncbi.nlm.nih.gov/31441678/.

Burke, Frances M. “Red Yeast Rice for the Treatment of Dyslipidemia.” Current Atherosclerosis Reports, U.S. National Library of Medicine, Apr. 2015, pubmed.ncbi.nlm.nih.gov/25728312/.

Esmailzadeh, Ahmad, et al. “Concentrated Pomegranate Juice Improves Lipid Profiles in Diabetic Patients with Hyperlipidemia.” Journal of Medicinal Food, U.S. National Library of Medicine, 2004, pubmed.ncbi.nlm.nih.gov/15383223/.

Houston, Mark. “The Role of Nutraceutical Supplements in the Treatment of Dyslipidemia.” Journal of Clinical Hypertension (Greenwich, Conn.), U.S. National Library of Medicine, 17 Jan. 2012, pubmed.ncbi.nlm.nih.gov/22277145/.

Huizen, Jennifer. “Dyslipidemia: Causes, Symptoms, and Treatment.” Medical News Today, MediLexicon International, 17 May 2018, www.medicalnewstoday.com/articles/321844.

Koppen, Laura M, et al. “Efficacy of Berberine Alone and in Combination for the Treatment of Hyperlipidemia: A Systematic Review.” Journal of Evidence-Based Complementary & Alternative Medicine, SAGE Publications, Oct. 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5871262/.

Medical Professionals, Cleveland Clinic. “Red Yeast Rice and Plant Stanols for Cholesterol Reduction.” Cleveland Clinic, 2022, my.clevelandclinic.org/health/articles/17417-cholesterol-reduction-red-yeast-rice-and-plant-stanols.

Pappan, Nikos, and Anis Rehman. “Dyslipidemia.” StatPearls [Internet]., U.S. National Library of Medicine, 15 July 2021, www.ncbi.nlm.nih.gov/books/NBK560891.

Disclaimer

An Integrative Approach To Dyslipidemia | Part 1

By
Dr. Alex Jimenez
-

Introduction

The body has a way to deal with unwanted pathogens that enter the body. The immune system will go and send out the inflammatory cells to the area to deal with the pathogen. Sometimes if the pathogen is still in the body, it can attach to the blood cells and lipids that are traveling throughout the entire body. This can cause chronic issues like metabolic syndrome, metabolic endotoxemia, and even dyslipidemia to the body. In this 2 part series, we will be taking a look at what dyslipidemia is, its symptoms, and how chronic inflammatory macro-and micronutrients can affect the cardiovascular system. Part 2 will be taking a look at what nutraceuticals are used to dampen the effects of dyslipidemia. By referring patients to qualified and skilled providers who specialized in cardiovascular services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

What Is Dyslipidemia?

Dyslipidemia is a condition where the lipid levels in the blood are either too high or too low. Research shows that when there is an imbalance of lipids, which includes cholesterol, LDL-C (low-density lipoprotein cholesterol), triglycerides, and HDL (high-density lipoprotein) are causes the development of atherosclerosis and over time other cardiovascular diseases. The most common underlying reasons for dyslipidemia are:

 

Even though these are all correct protective/defense mechanisms that can help the body when acute illnesses are affecting the organ systems, they can turn into chronic illnesses over time when unwanted pathogens start to attach themselves to any of the organ systems and cause havoc to the body. Some of the most common reasons for these vascular responses include:

  • Chronic inflammatory macro- and micro-nutrient intake.
  • Chronic infections (all types including bacteria, virus, fungi, TB, and parasites).
  • Toxins, POPs (persistent organic pollutants), and heavy metals.
  • Metabolic, inflammatory, immune, toxic, and infectious endotoxemia.

 

Plasma Lipoproteins Are Important

Lipoproteins prevent infections, protect against toxins, and inflammatory nutrition as they are a component of innate immunity. Studies have found that lipoproteins are complex particles in the body that has a central core containing cholesterol esters and triglycerides and plasma lipoproteins can be divided into seven classes based on their lipid composition. Since all lipids and lipoproteins are anti-infective and protect against endotoxin and inflammation-induced vascular damage, they can all detoxify microbial LPS-lipopolysaccharide (gram-negative bacteria) and LTA-lipoteichoic acid (gram-positive bacteria) while binding to LPS to prevent LPS–induced activation of monocytes, macrophages, and pro-inflammatory cytokines.

 

 

Other studies have found that plasma lipoproteins are the essential vehicles for lipid distributions for the body’s cellular energy, structural requirements, and excreting out excess lipids out of the body. When there are imbalances in the lipoprotein metabolism that can contribute to metabolic diseases that can range from vascular inflammation to obesity and diabetes. However, as the lipids become modified they become vasculotoxic. The vascular system and heart become “ innocent bystanders” that are injured during the acute, correct defensive/protective responses which will induce atherosclerosis and chronic heart disease.

 

Dyslipidemia Symptoms

Since cardiovascular disease is involved in the cardiovascular system, dyslipidemia is one of the risk factors that can harm the body. Studies have found that dyslipidemia is considered a metabolic abnormality that can lead to a persistent increase in the plasmatic concentration of cholesterol and triglycerides, being the common cause of morbidity. Other research studies have found that many individuals are unaware that they have dyslipidemia unless it is severe and it is found in a routine blood test. Other symptoms that dyslipidemia can cause in the body include:

 

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

As a form of regenerative medicine, HCTP (human cellular tissue products) or stem cells* are used to help boost the body’s own natural healing process from injuries. Both national and international affiliated clinics and distribution organizations, use HCTP therapy to help repair and regenerate these damaged cells, tissues, and organs back to their original state, so the body can heal faster and the individual can continue on their wellness journey.

Chronic Inflammatory Macro- and Micronutrients

Since the gut plays a role in inflammation and is connected to other organ systems like the brain and the cardiovascular system, it can cause the body to develop chronic inflammation if it is not treated right away.  Studies have found that when there are structural changes in the intestinal epithelium that are due to diet alternations can become the results of increasing plasma lipoproteins to induce chronic low-grade inflammation in the body. An inflammatory diet will increase circulating endotoxin levels and with positive correlation with an increase in TC, LDL-C, TG, and decreasing in HDL-C and dysfunctional HDL. This will also correlate with obesity, WC( waist circumference), WHR (waist/hip ratio), insulin levels, IR (insulin resistance), T2 DM, inflammatory cytokines, NAFLD (non-alcoholic fatty liver disease). When this happens, metabolic endotoxemia will begin to cause a commotion.

 

Metabolic Endotoxemia & CHD

 

Research studies show that metabolic endotoxemia is a condition where lipopolysaccharide (LPS) levels are elevated despite the presence of any infections that are in the body. Since the gut microbiota signatures (GMS) act as important determinants in the pathogenesis of inflammatory induced obesity, CHD, atherosclerosis, and T2 DM, having metabolic endotoxemia can cause gut dysbiosis and chronic inflammatory diseases that stimulate the innate immune system, TLR4 in adipocytes and vascular tissue, activates NFkB increases inflammation, oxidative stress, and immune dysfunction. While LPS ( lipopolysaccharide) from gram-negative bacteria is the endotoxin from the cell wall that has a high affinity for chylomicrons and cross enterocyte barrier coupled with lipoproteins.

 

Conclusion

All in all, the body has a way to make sure that no unwanted pathogens attach themselves into the bloodstream and cause chronic issues to cause the body pain. When there are high levels or low levels of lipids that are causing cardiovascular disease risk factors to rise, it can cause the body to be dysfunctional. By incorporating heart-healthy and anti-inflammatory foods and supplements into the body, can provide the necessary nutrients to the body and its organ systems, it can dampen the effects of chronic diseases and the body can begin its recovery process.

 

References

Ama Moor, Vicky Jocelyne, et al. “Dyslipidemia in Patients with a Cardiovascular Risk and Disease at the University Teaching Hospital of Yaoundé, Cameroon.” International Journal of Vascular Medicine, Hindawi Publishing Corporation, 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5253480/.

Feingold, Kenneth R. “Introduction to Lipids and Lipoproteins.” Endotext [Internet]., U.S. National Library of Medicine, 19 Jan. 2021, www.ncbi.nlm.nih.gov/books/NBK305896/.

Fuke, Nobuo, et al. “Regulation of Gut Microbiota and Metabolic Endotoxemia with Dietary Factors.” Nutrients, MDPI, 23 Sept. 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6835897/.

Huizen, Jennifer. “Dyslipidemia: Causes, Symptoms, and Treatment.” Medical News Today, MediLexicon International, 17 May 2018, www.medicalnewstoday.com/articles/321844.

Li, Kang, et al. “Isolation of Plasma Lipoproteins as a Source of Extracellular RNA.” Methods in Molecular Biology (Clifton, N.J.), U.S. National Library of Medicine, 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6476197/.

Mohammad, Shireen, and Christoph Thiemermann. “Role of Metabolic Endotoxemia in Systemic Inflammation and Potential Interventions.” Frontiers, Frontiers, 11 Jan. 2021, www.frontiersin.org/articles/10.3389/fimmu.2020.594150/full.

Pappan, Nikos, and Anis Rehman. “Dyslipidemia.” StatPearls [Internet]., U.S. National Library of Medicine, 15 July 2021, www.ncbi.nlm.nih.gov/books/NBK560891.

Disclaimer

Body Stretching Fundamentals

By
Dr. Alex Jimenez
-
Happy young woman in activewear stretching towards foot while sitting on mat during workout in gym

 Stretching Fundamentals: Stretching benefits the body by keeping the muscles flexible, strong, healthy, and able to maintain optimal physical performance. As with any other discipline stretching correctly requires using the proper form, correct technique, and practicing regularly. The angles need to be accurate; the body has to move at the right speed and maintain correct posture. The focus should be moving the joint as little as possible as the muscle/s stretch and elongate.

Body Stretching Fundamentals

Stretching Fundamentals

Stretching should become a daily activity that turns into a healthy habit. The muscles need frequent maintenance from daily/nightly bending, twisting, reaching, carrying, and lifting work. This is especially true for individuals dealing with constant soreness, aches, pains, and problems with tight, tense, and stressed-out muscles. When the body is stressed, heart rate increases, and individuals tend to tighten up. Stretching benefits include:

  • Stress relief.
  • Increased muscle blood flow.
  • Increased body flexibility.
  • Helps joints move through their full range of motion.
  • Improves performance in physical activities.
  • Decreases soreness, aches, and pains.
  • Injury prevention.
  • Improves posture.
  • Improves sleep.
  • Preps the body for exercise and activities.
  • Improves mental health.

Human nature is to take the path of least resistance, which makes the body feel flexible and comfortable. This is a common reason individuals consider stretching unnecessary or too painful to engage in. However, stretching fundamentals need to be maintained as stretching carelessly or poorly can negatively affect other muscles and joints and worsen injuries/conditions. 

Guidelines

To stretch safely, it is recommended to do a proper warm-up, stretch slowly, working the right muscles and joints. The guidelines make stretching safer, more effective, and increase body awareness.

Warm-Up

  • Warming the muscles increases blood flow.
  • Warming up muscles before physical activity/workout is crucial for preventing injuries and maximizing effectiveness.
  • Stretching cold muscles activates a reflex that prevents overstretching, resulting in shortening and tightening of the muscles.
  • A healthy warm-up should consist of light cardio and dynamic stretches for the major muscle groups.
  • Dynamic stretching involves moving into and out of positions through a full range of motion rather than holding a stretch for a prolonged period.
  • Dynamic stretches are recommended to be held for 2-3 seconds for 4-6 repetitions.

Take It Slow

  • Stretching out too fast can make the body think that the muscle is about to get torn or injured.
  • To protect the muscle, it contracts, preventing it from reaching the full stretch.
  • This is why the correct technique needs to be observed.
  • A couple of degrees in the wrong direction can mean the difference between a healthy stretch and pulling a joint capsule causing injury.

Body Composition

Muscle Recovery

When engaged in physical activity, exercise, or working, microscopic tears are happening to muscle cells. Because of the body’s stress and fatigue, hormone and enzyme levels fluctuate, and inflammation increases. This helps in fat loss, increases metabolism, increases strength and muscle growth. However, these benefits only happen with proper recovery. Different types of recovery include:

Immediate Recovery

  • These are the quick moments’ in-between physical movements.
  • For example, the time between each stride when jogging.

Short-Term Recovery

  • This is the time between activities or sets of exercises.
  • For example, the rest periods between doing a heavy job or sprint intervals.

Training Recovery

  • This is the time between when one workout or job ends, and the next begins.

There is no one size fits all, as everyone’s body is different; it is recommended to consult with a trainer or fitness expert and experiment with what feels right.

  • For some individuals, 24 hours is enough.
  • For others, it can take 48 or 72 hours to feel fully recovered.
  • Other factors that affect recovery are:
  • Age
  • Fitness level
  • Work/exercise intensity
  • Diet
  • Sleep
References

Behm, David G, and Anis Chaouachi. “A review of the acute effects of static and dynamic stretching on performance.” European Journal of applied physiology vol. 111,11 (2011): 2633-51. doi:10.1007/s00421-011-1879-2

Freitas, S R et al. “Stretching Effects: High-intensity & Moderate-duration vs. Low-intensity & Long-duration.” International journal of sports medicine vol. 37,3 (2016): 239-44. doi:10.1055/s-0035-1548946

Hotta, Kazuki et al. “Daily muscle stretching enhances blood flow, endothelial function, capillarity, vascular volume and connectivity in aged skeletal muscle.” The Journal of physiology vol. 596,10 (2018): 1903-1917. doi:10.1113/JP275459

Kataura, Satoshi et al. “Acute Effects of the Different Intensity of Static Stretching on Flexibility and Isometric Muscle Force.” Journal of strength and conditioning research vol. 31,12 (2017): 3403-3410. doi:10.1519/JSC.0000000000001752

Emerging Nutraceuticals For Metabolic Cardiology | Part 2

By
Dr. Alex Jimenez
-

Introduction

The heart’s primary role in the cardiovascular system is to make sure that blood, nutrients, and hormones are being transported throughout the entire body. The cardiovascular system is consist of the arteries, veins, and blood vessels that are throughout the body and this system make sure to pump blood into the organs and tissues. When there are pathogens that cause the cardiovascular system to develop cardiac risk factors, it can cause many chronic issues over time and can potentially harm the body. In this 2 part series, we will be taking a look at what is diastolic dysfunction in the cardiovascular system and how different nutraceuticals can prevent heart disease from rising in the body. Part 1 took a look into what is cardiac metabolism and how HCTP can help renew the cardiovascular system. By referring patients to qualified and skilled providers who specialized in cardiovascular services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

What Is Diastolic Dysfunction?

The diastolic function requires more cellular energy than systolic contraction as higher concentrations of ATP are required to activate calcium pumps necessary to facilitate cardiac relaxation and diastolic filling. Studies show that diastolic dysfunction is a collective number of issues from hypertension, diabetes, age, and left ventricular hypertrophy that causes increased levels of cardiac oxidative stress and cardiac ROS in the heart.

 

Surprisingly, diastolic dysfunction is more common in women with hypertension, IHSS, MVP, and infiltrative cardiomyopathy, and the best way to know the early signs of myocardial failure due to diastolic despite the adequate systolic function in the heart. The energetic imbalance of diastolic heart failure is characterized by an increase in energy demand and a decrease in energy production, transfer, and substrate utilization resulting in an ATP deficit. The biopsies of heart tissue in heart failure
patients reveal diminished quantities of ATP in the mitochondria and studies show that diastolic heart failure occurs when the left ventricle is unable to accept adequate volumes of blood.

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

*Stem cells or HCTP (human cellular tissue products) are used in therapeutic regenerative treatments that affiliated clinics and distribution organizations (both international and national) provide for anyone that needs treatment. HCTP therapy utilizes HCTP to help repair and regenerate damaged cells, tissues, and organs back to their original state. As research studies continue to look into HCTP therapy, the result shows that HCTP can help rescue damaged heart cells and regenerate new heart muscle cells after the individual has been affected by cardiovascular diseases. Part 1 explains more about how HCTP can help repair damaged heart cells.

Nutraceuticals For Heart Disease

 

Surprisingly though there are nutraceuticals that can help dampen the effects of heart disease and help improve diastolic function to be regulated at normal levels. Studies have shown that even though cardiovascular disease ranks as the most common health issue, by providing several heart-healthy food and dietary supplements has been shown to protect against the development of cardiovascular diseases. Some of the nutraceuticals that can help lower the risk of heart disease are:

  • CoQ10
  • L-carnitine
  • D-ribose

 

CoQ10

Studies have shown that CoenzymeQ10 or CoQ10 can help decrease levels of neurodegenerative diseases, fibromyalgia, diabetes, and heart failure in the body. This essential compound has helped synthesized the mitochondrial inner membrane of the human body while also becoming the key component to transport electron chains in the cellular mitochondria, which is absolutely necessary for ATP production.

 

CoQ10 Effects

Since CoQ10 is a ubiquitous factor that is presented in the cell membranes and the mitochondria, research shows that CoQ10 has significant antioxidant and anti-inflammatory properties that can provide therapeutic results for individuals with cardiovascular diseases. Some of the beneficial effects that CoQ10 can offer to the heart include:

  • Reduces Lp(a)
  • Improves endothelial function
  • Decreases cholesterol/triglyceride levels
  • Increases HDL
  • Decreases FBS/HbA1c
  • Reduces lipoprotein (LDL) oxidation
  • Reduces systolic/diastolic blood pressure

 

L-carnitine

L-carnitine is a trimethylated amino acid-like cofactor for the transport of free long-chain fatty acids in the mitochondrial matrix where beta-oxidation occurs for cellular energy production. L-carnitine was originally isolated from meat in 1905 and it plays a crucial role in metabolism as it was discovered in 1955. Studies have shown that when patients are undergoing hemodialysis will often have carnitine deficiencies, which will result in cardiac dysfunction. However, like CoQ10, carnitine deficiency is usually not a factor in a healthy, well-nourished population consuming adequate animal protein.

 

L-carnitine Effects

Some of the beneficial factors that L-carnitine can provide to the body is that it actually plays an important role in transporting long-chain fatty acids from the cytoplasm into various tissues in the body. Other beneficial effects that L-carnitine provides include:

  • Beta oxidation of fatty acids – in mitochondria
  • 60% of heart energy metabolism of fatty acids
  • Removal of lactic acid and other toxic metabolites from blood
  • Ammonia detoxification
  • Function as antioxidants
  • Next-generation – Aminocarnitines

 

D-ribose

The administration of D-ribose can help with the improvement in diastolic function as D-ribose is used by cells to manage cellular energy restoration. It helps replenish the body as the loss of purines in the ischemic situation can cause a slow process to replace the adenine pool. If D-ribose is not available energy pool, then it cannot be restored and the heart can take about 100 days to restore ATP via de novo synthesis. Studies have found that D-ribose is actually an essential component for the respiratory, skeletal, and nervous systems while providing beneficial effects to the heart.

 

D-ribose Effects

Research studies have found that D-ribose is a naturally occurring pentose carbohydrate that has beneficial properties by increasing cellular energy levels, improving function that follows ischemia, and dampening the effects of cardiovascular disease. Other beneficial effects that D-ribose can provide include:

  • Improves treadmill findings in patients with coronary artery disease
  • Better diastolic function, QOL, and functional status in chronic heart failure
  • Accelerates the recovery of systolic function post CABG
  • Speeds recovery of muscle ATP following anaerobic exercise
  • Enhances strength and endurance gain with weight training
  • Decreases free radical stress during anaerobic exercise
  • Benefit in fibromyalgia

 

Conclusion

All in all, nutraceuticals are beneficial by dampening the effects of diastolic dysfunction and cardiovascular diseases. When unwanted pathogens start attacking the body, cause many inflammatory problems that can turn into chronic issues over time, causing a person to be miserable. By finding the right kind of vitamins, eating the right foods, and regularly exercising can help the body and cardiovascular system be functional throughout the entire lifetime.

 

Reference

Jeong, Euy-Myoung, and Samuel C Dudley. “Diastolic Dysfunction.” Circulation Journal: Official Journal of the Japanese Circulation Society, U.S. National Library of Medicine, 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4861951/.

Kaneko, Mai, et al. “L-Carnitine Improved the Cardiac Function via the Effect on Myocardial Fatty Acid Metabolism in a Hemodialysis Patient.” Internal Medicine (Tokyo, Japan), The Japanese Society of Internal Medicine, 15 Dec. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6355401/.

Lalande, Sophie, and Bruce D Johnson. “Diastolic Dysfunction: A Link between Hypertension and Heart Failure.” Drugs of Today (Barcelona, Spain: 1998), U.S. National Library of Medicine, July 2008, www.ncbi.nlm.nih.gov/pmc/articles/PMC2713868/.

Li, Shuai, et al. “D-Ribose: Potential Clinical Applications in Congestive Heart Failure and Diabetes, and Its Complications (Review).” Experimental and Therapeutic Medicine, D.A. Spandidos, May 2021, www.ncbi.nlm.nih.gov/pmc/articles/PMC8005739/.

Martelli, Alma, et al. “Coenzyme Q10: Clinical Applications in Cardiovascular Diseases.” Antioxidants (Basel, Switzerland), MDPI, 22 Apr. 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7222396/.

Medical Professionals, Cleveland Clinic. “Stem Cell Therapy for Heart Disease.” Cleveland Clinic, 30 Jan. 2019, my.clevelandclinic.org/health/diseases/17508-heart-disease-stem-cell-therapy.

Shecterle, Linda M, et al. “Potential Clinical Benefits of D-Ribose in Ischemic Cardiovascular Disease.” Cureus, Cureus, 9 Mar. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC5943027/.

Sood, Brittany, and Michael Keenaghan. “Coenzyme Q10.” StatPearls [Internet]., U.S. National Library of Medicine, 19 Jan. 2022, www.ncbi.nlm.nih.gov/books/NBK531491/.

Sosnowska, Bozena, et al. “The Role of Nutraceuticals in the Prevention of Cardiovascular Disease.” Cardiovascular Diagnosis and Therapy, AME Publishing Company, Apr. 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5418215/.

Zozina, Vladlena I, et al. “Coenzyme Q10 in Cardiovascular and Metabolic Diseases: Current State of the Problem.” Current Cardiology Reviews, Bentham Science Publishers, 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6131403/.

Disclaimer

The Emerging Frontier In Metabolic Cardiology | Part 1

By
Dr. Alex Jimenez
-

Introduction

The heart’s purpose in the cardiovascular system is to make sure that oxygen-riched blood, nutrients, and hormones are being pumped and transported throughout the body and into the muscle tissues and organs that need it. When there are pathogens that enter into the bloodstream, it can cause many risk factors to the cardiovascular system, it can lead to chronic symptoms over time if it is not treated right away. In this 2 part series, we will be taking a look at cardiac metabolism and how HCTP can help renew the cardiovascular system. Part 2 will be discussing what is diastolic dysfunction in the cardiovascular system and how different nutraceuticals can help prevent heart disease from rising. By referring patients to qualified and skilled providers who specialized in cardiovascular services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

What Is Cardiac Metabolism?

 

Since the heart’s job is to make sure that blood is pumping throughout the body, studies have found that the network for cardiac fuel metabolism contains an intricate set of interacting pathways that produces endpoint results for both ATP-producing and non-ATP-producing energy. However, when there are pathogens that are affecting the cardiac metabolism it can lead to chronic conditions like congestive heart failure. Research studies have shown that congestive heart failure is an energy-starved heart and is associated with metabolic changes in the body, it can cause a progressive impairment of cardiac and musculoskeletal high energy phosphate production in the heart. This will decrease ATP concentration causing serious defects in cellular metabolism and causing pulsation of the cellular structure in the heart muscles. With the roles of ATP vs. oxygen in myocyte of the cellular structure can also play their parts when dealing with modulating cardiac metabolism as a therapeutic approach to heart failure.

 

Cellular Mitochondria

Also known as the powerhouse of cells, the cellular mitochondria contain about 3500 – 5000 mitochondria, and the myocyte contains 35% of the entire cell. Research shows that the cellular mitochondria can help take the food that a person eats and turn it into energy for the cells can use. This helps ATP to formed in mitochondria and transfer to the cytosol to supply energy to the cell. There are 2 functions that the cellular mitochondria provide for the body while making sure that the cellular structure is healthy. The mitochondrial respiration is not all oxygen, that is converted to CO2 and water in the body but contains about 3-5% of oxygen, which are toxic free radicals. Mitochondrial DNA is more similar to bacterial DNA unlike nuclear DNA and provides defensive mechanisms that are just emerging and have proven to be very useful for tracing genetic lines.

 

Heart Disease

With 100,000 cases of new-onset chronic heart failure that are continuing to pop up around the world, research shows that heart disease can be numerous conditions that can affect the heart muscle. Some of the conditions with chronic heart disease actually depend on the symptoms of the heart disease a person may have. However, some of the common symptoms that can happen to the heart include nutritional factors like fast foods to mitochondrial failure in the body’s cellular structure. Even inflammation in the body is one of the symptoms of heart disease. For many individuals, there is a biochemical/metabolic connection to heart disease, since each of the organ systems is connected to each other and there is ATP nutriceutical support that can help lower the risk for heart disease.

 

Bioenergetics & The Heart

 

When there is dysfunctional energy in diseased hearts, angina, chronic heart failure, PTCA, CABG can cause heart risk factors to rise in the body, causing unwanted issues to affect a person. Chronic coronary artery disease with ischemia and/or silent ischemia can cause severe energy deprivation to occur. Any intervention that will slow the rate of ATP degradation and speed-up recovery rate will minimize heart damage and enhance cardiac function since chronic heart failure is energy-starved causing about 30% of all energy lost to the heart. This will cause low intra-myocardial ATP and reduced myocardial contraction but through bioenergetic therapy and even regenerative medicine can help the myocardial tissue may be restored significantly by oral supplements like Coenzyme Q10, Carnitine, D-Ribose to restore ATP dynamics in the heart.

 

HCTP & The Heart

 

Known throughout the world as *stem cells, HCTP or human cellular tissue products can help repair the damaged heart muscles from cardiovascular diseases. There is still more research being done with HCTP and its uses as a form of regenerative medicine as research shows that HCTP is nature’s own transformer and when the body is injured, HCTP is injected into the damaged heart muscle and repairing the damaged heart cells to be turned into new heart muscles. However, nationally and internationally affiliated clinics and distribution organizations are authorized to use HCTP in their practices since it has to be FDA-approved. Other research studies have shown that HCTP can help alleviate morbidity and mortality symptoms for patients that are dealing with heart damage from a variety of insults that has affected the heart.

 

HCTP Therapy

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HCTP therapy is a form of regenerative therapy that utilizes HCTP (human cellular tissue products) or stem cells* to help repair and regenerate damaged tissue, cells, and organs back to their original state. HCTP is used in affiliated clinics and distribution organizations (both international and national) that provided regenerative therapy to individuals that are dealing with chronic issues that are affecting their bodies.

Conclusion

All in all, the cardiovascular system makes sure that the heart is doing its job pumping blood throughout the entire body and keeping it functional. When there are unwanted risk factors that are affecting the heart, it can cause chronic symptoms to develop in the body over time and cause serious damage to the heart. By utilizing nutraceuticals, therapeutic treatments to alleviate the chronic symptoms that are damaging the heart, the body can recover and the cardiovascular system can continue to do its job.

 

References

Hare, Joshua M, and Sandra V Chaparro. “Cardiac Regeneration and Stem Cell Therapy.” Current Opinion in Organ Transplantation, U.S. National Library of Medicine, Oct. 2008, www.ncbi.nlm.nih.gov/pmc/articles/PMC3966209/.

Kolwicz, Stephen C, et al. “Cardiac Metabolism and Its Interactions with Contraction, Growth, and Survival of Cardiomyocytes.” Circulation Research, 16 Aug. 2013, www.ahajournals.org/doi/10.1161/CIRCRESAHA.113.302095.

Medical Professionals, Cleveland Clinic. “Stem Cell Therapy for Heart Disease.” Cleveland Clinic, 3 Jan. 2019, my.clevelandclinic.org/health/diseases/17508-heart-disease-stem-cell-therapy.

Newman, Tim. “Mitochondria: Form, Function, and Disease.” Medical News Today, MediLexicon International, 8 Feb. 2018, www.medicalnewstoday.com/articles/320875.

Rosano, Giuseppe Mc, and Cristiana Vitale. “Metabolic Modulation of Cardiac Metabolism in Heart Failure.” Cardiac Failure Review, Radcliffe Cardiology, Aug. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6125709/.

Staff, Mayo Clinic. “Heart Disease.” Mayo Clinic, Mayo Foundation for Medical Education and Research, 9 Feb. 2021, www.mayoclinic.org/diseases-conditions/heart-disease/symptoms-causes/syc-20353118.

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