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Complications Poor Posture

By
Dr. Alex Jimenez
-
Copy machine. Young woman in jeans and a green blouse bending over a copy machine, serious attentive.

As the body gets older, slouching, little to no physical activity, and regular stretching cause muscle fatigue, weakness, tension, leading to poor posture complications. The complications include:

  • Back and neck pain
  • Rounded shoulders
  • Spinal dysfunction
  • Joint degeneration
  • Sleep problems
  • Chronic pain

Posture can be improved along with overall spinal health and a better quality of life through chiropractic treatment. Chiropractic will improve posture through adjustments, postural exercise training and stretching, education on ergonomics, and nutrition to strengthen the body.

Complications Poor Posture

Complications Poor Posture

Symptoms

Symptoms vary as they depend on the severity of the case and condition.

  • Muscle fatigue/weakness
  • Body aches and soreness
  • Back pain
  • Rounded shoulders
  • Standing and/or walking problems
  • Headaches
  • Potbelly

Mechanisms

Poor posture leads to dysfunction and interference with the body’s postural mechanisms. These include:

Muscle Fibers

Skeletal muscle comprises two types of muscle fiber. They are static or slow-twitch muscles and phasic or fast-twitch muscles. Static muscle fibers are found in the deeper muscle layers. Static fibers burn energy slowly and keep working without tiring. They help the body maintain posture without effort and contribute to balance by sensing the body’s position and transmitting the information to the brain. Phasic muscle fibers are used for movement and activity but can quickly run out of energy. Poor posture causes muscle fatigue because the phasic fibers are used rather than the static fibers to maintain the body’s proper position.

Muscle Strength and Length

Over time, the body constantly needs support from the phasic muscle fibers. This causes the deeper supporting muscles to waste away because they are not being used. Weak, unused muscles begin to tighten, causing a shortening of muscle length that can compact the spine’s bones and cause back complications.

Nervous System Feedback

The deeper layers of muscle sense the body’s position in space and relay this information to the brain. The brain does not receive complete transmission if the phasic muscle fibers take over this function. The brain assumes that the body needs to be propped up/corrected to counteract the poor posture effects, triggering further muscle contraction, adding to the fatigue and pain.

Listening To The Body

The objective is to form a habit of regularly listening to what the body is saying. Make minor adjustments while standing and sitting throughout the day/night. Often what happens is individuals become so immersed in their work, school tasks that they ignore any physical discomfort and push through and forget to change positions/move around to get the muscles moving and the blood pumping. If there is muscle tension or fatigue, don’t just work through the pain; move into another healthy position.

Posture Improvement

Suggestions include:

Body Composition

Strength Training

As the body ages, it loses muscle mass, known as sarcopenia. Between the ages of 30 and 80, both men and women can lose 30-50 percent of their muscle strength. Decreasing strength can make it a challenge to lead an active lifestyle or have energy levels to complete the daily errands. Individuals can be reluctant to improve fitness levels through resistance workouts believing there is nothing left after years of inactivity. This is not true as anybody can strength train. With the right mindset, and health coaching team, goals can be set to:

  • Improve body composition
  • Improve energy levels
  • Maintain an active lifestyle
References

Creze, Maud et al. “Posture-related stiffness mapping of paraspinal muscles.” Journal of anatomy vol. 234,6 (2019): 787-799. doi:10.1111/joa.12978

Deliagina, Tatiana G et al. “Physiological and circuit mechanisms of postural control.” Current opinion in neurobiology vol. 22,4 (2012): 646-52. doi:10.1016/j.conb.2012.03.002

Korakakis, Vasileios et al. “Physiotherapist perceptions of optimal sitting and standing posture.” Musculoskeletal Science & practice vol. 39 (2019): 24-31. doi:10.1016/j.msksp.2018.11.004

Pollock, A S et al. “What is balance?.” Clinical rehabilitation vol. 14,4 (2000): 402-6. doi:10.1191/0269215500cr342oa

Waters, Thomas R, and Robert B Dick. “Evidence of health risks associated with prolonged standing at work and intervention effectiveness.” Rehabilitation nursing: the official journal of the Association of Rehabilitation Nurses vol. 40,3 (2015): 148-65. doi:10.1002/rnj.166

How Gut Disorders Affect The GI Motility | Part 2

By
Dr. Alex Jimenez
-

Introduction

Part of the digestive system’s primary system is to make sure that the food that a person is consuming is being digested and excreted out. The digested food is packed with vitamins and nutrients that the immune system, muscle tissues, cells, organs, and the body needs to function correctly. When unwanted pathogens or disruptors enter the body and travel through the gut system, it can cause chronic issues to develop and cause harm to each of the systems. However, many treatments can help both the body and the gut system dampen the effects and make the body feel better. In this 2 part series, we will be looking at how gastrointestinal disorders can affect the gut and what kind of treatments dampen their effects. Part 1 looked at the GI tract and how each organ functions in the digestive system, and how the enteric nervous system and each muscle cells work together. By referring patients to qualified and skilled providers who specialize in gastroenterology services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, it may. If you are uncertain, here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

Disorders Of GI Motility

 

When pathogens start to enter the body and affect the gut system, many problems will affect the gut and the body itself. These are known as gastrointestinal motility disorders. Research shows that gastrointestinal motility disorders have many signs and symptoms that can occur anywhere throughout the luminal gastrointestinal tract. Some of these disorders can affect:

  • Gastric motility
  •  Small intestinal motility
  • Colon and anorectal motility

These disorders can cause many gut issues and diseases like SIBO, gastroparesis, constipation, diarrhea, and IBS (irritable bowel syndrome) to make a person feel miserable and cause pain if not treated. Other research studies have found that gastrointestinal dysmotility can also cause a delay in gastric emptying and cause obstruction in the large and small intestines. When this happens, the consumed food will not be able to pass through the intestines, and the intestinal muscles will have contractions causing the individual to be in pain.

 

Gastroparesis

Gastroparesis is derived from the Greek words “gastro” and “paresis,” which means partial paralysis of the stomach. Research studies have shown that gastroparesis is a condition of collective symptoms like bloating due to nausea and vomiting that causes delayed emptying of the stomach in the absence of mechanical obstruction. Some of the most common signs that are caused by gastroparesis include:

  • Nausea 
  • Abdominal pain
  • Early satiety
  • Vomiting

The symptoms can vary from intermittent to severe, depending on how sour the stomach is. In a normal gut function, the proximal stomach will expand to accommodate the food consumed, and the intragastric pressure is maintained. The food solids are broken down into 1-2 mm particles with contractions causing the gastric emptying to be 50% in 2 hours and 90% in 4 hours. With gastroparesis, the stomach will lose all of the accommodations and alter the antral phasic contractions causing the stomach to be in visceral hypersensitivity.

 

Irritable Bowel Syndrome

 

Irritable bowel syndrome or IBS is a functional bowel disorder that causes chronic or recurrent abdominal pain or discomfort in the large intestines. Research shows that IBS is a chronic condition caused by numerous factors that cause IBS to be severe in some people who may have it. With IBS being associated with altered bowel habits and the absence of organic abnormalities, some of these factors that can cause IBS in the body are:

  • Documented weight loss
  • Nocturnal symptoms
  • Fevers, chills, recent travel to endemic regions
  • Severe unrelenting large-volume diarrhea
  • Family history of colon cancer
  • Recent antibiotic use
  • Abnormal physical exam findings

Other research studies have found that since IBS is a type of GI disorder, it can cause the brain-gut connection to have problems and cause the digestive tract to be susceptible. Any abdominal pain or discomfort with altered defecation that IBS causes can cause prominent bloating associated with stress or comorbid conditions.

Common Gut Disorders In The Gut

Common Disorders of the Digestive System

Many common gut disorders can affect the gut system and cause personal discomfort and pain if it is not treated right away. Utilizing gut-healthy foods like probiotics, a change in a particular lifestyle can provide beneficial results in lowering gut disorders and dampening their effects. This will allow the gut to heal, and many individuals will begin to continue with their daily activities without gut issues.

Treatments For GI Motility Disorders

There are many treatments to help the gut system and dampen GI motility’s effects on the gut. Many individuals have done a 180 turn on their lifestyles by changing their eating habits and taking out the foods causing them to have gut issues. By incorporating some of these treatments, many individuals can start feeling better, knowing that the issue is causing them gut problems can be resolved. Some of the treatments that can lower GI motility disorders include:

  • Melatonin
  • Herbal therapy
  • Probiotics
  • Elimination diets
  • Peppermint
  • Laxatives
  • Fibers

 

Fiber

An increased fiber intake is an initial treatment to help dampen the effect of GI motility disorder. It is available in a large variety of supplements and foods that are low cost, safe, and easy to use. Research studies have shown that fiber can cause an increase in the frequency of bowel movements. Since fiber is consists of cell walls that resist digestion and maintain the water by increasing the stool mass/bulk to be excreted out of the body and provide relief. It is essential to consume water with fiber for the bowel movement to be exerted without any issues. Studies have shown that dietary fibers are integral to a balanced diet. When individuals consume a high fiber diet, it can provide many physiological and metabolic benefits to the body.

Conclusion

All in all, it is important to have a healthy diet and a change in lifestyle habits to ensure that the gut is working properly. When there are unwanted pathogens that start to infect the gut, it can develop into chronic issues over time causing the person to be in pain. Utilizing many therapeutic treatments can be beneficial to the gut and help the individual be pain-free.

 

References

Deane, Adam M, et al. “Pathophysiology and Treatment of Gastrointestinal Motility Disorders in the Acutely Ill.” Nutrition in Clinical Practice: Official Publication of the American Society for Parenteral and Enteral Nutrition, U.S. National Library of Medicine, Feb. 2019, pubmed.ncbi.nlm.nih.gov/30294835/.

Hillemeier, C. “An Overview of the Effects of Dietary Fiber on Gastrointestinal Transit.” Pediatrics, U.S. National Library of Medicine, Nov. 1995, pubmed.ncbi.nlm.nih.gov/7494680/.

Lacy, Brian E, and Kristen Weiser. “Gastrointestinal Motility Disorders: An Update.” Digestive Diseases (Basel, Switzerland), U.S. National Library of Medicine, 2006, pubmed.ncbi.nlm.nih.gov/16849850/.

Medical Professionals, Cleveland Clinic. “Irritable Bowel Syndrome: IBS, Symptoms, Causes, Treatment.” Cleveland Clinic, 24 Sept. 2020, my.clevelandclinic.org/health/diseases/4342-irritable-bowel-syndrome-ibs.

Reddivari, Anil Kumar Reddy, and Parth Mehta. “Gastroparesis.” StatPearls [Internet]., U.S. National Library of Medicine, 31 Dec. 2021, www.ncbi.nlm.nih.gov/books/NBK551528/.

Staff, Mayo Clinic. “Irritable Bowel Syndrome.” Mayo Clinic, Mayo Foundation for Medical Education and Research, 1 Dec. 2021, www.mayoclinic.org/diseases-conditions/irritable-bowel-syndrome/symptoms-causes/syc-20360016.

Suresh, Harsha, et al. “Rheological Characteristics of Soluble Fibres during Chemically Simulated Digestion and Their Suitability for Gastroparesis Patients.” Nutrients, MDPI, 17 Aug. 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7468937/.

Disclaimer

Autonomic Functions Of The Gut | Part 1

By
Dr. Alex Jimenez
-

Introduction

The digestive system is home to the gut, the gastrointestinal (GI) tract, the liver, the intestines, and other organs that make sure that the consumed food is being digested and the nutrients from the digested foods are being transported to all the necessary systems, muscles, tissues, and cells while the bile is excreted out of the body. In this 2 part series, we will be taking a look at the GI tract and how each organ functions in the digestive system as well as how the enteric nervous system and how each muscle and cells work together. Part 2 will be taking a look at how gastrointestinal disorders can affect the gut and what kind of treatments dampen their effects. By referring patients to qualified and skilled providers who specialized in gastroenterology services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, it may. In case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

What Is The GI Tract?

 

So the gastrointestinal tract or the GI tract is part of the digestive system where it’s a long tube that is connecting to hollow organs to not only digest food but also excrete it out of the body as well. Research studies have shown that the GI tract works together with the central nervous system and the circulatory system by utilizing the body’s nerves, hormones, bacteria, blood, and organs to help digest the foods and liquids while providing the nutrients to make the body work properly. The sphincters in the GI tract include:

  • Upper esophageal
  • Lower esophageal
  • Pylorus
  • Sphincter of Oddi
  • Ileocecal valve
  • Internal and external anal sphincters

The GI motility is a tightly integrated system that is regulated by the enteric nervous system while being responsible for mixing, propulsive, and organized patterns of movements. Other research studies have shown that the GI tract in the digestive system helps the body receive nutrients like carbohydrates, proteins, fats, minerals, and vitamins to help the body absorb them to promote new energy, growth, and repairing the cellular structure. Some of the organs that help the GI tract stay functional are:

  • Esophagus
  • Stomach
  • Small intestine
  • Colon
  • Anorectum

 

The Stomach

Research studies show that the stomach is a j-shaped organ that helps produces enzymes and acids to break down food to be transported to the small intestines. The stomach’s function is to accommodate and store food temporarily while also regulating intragastric pressure in the stomach. The stomach also provides a tonic movement of chyme and doesn’t have a phasic motor activity unless it is grinding the food into particles.  Research also shows that the stomach has 4 different tissue layers that help the stomach surfaces to increase the gastric mucosa to allow gastric expansion with food ingestion. Once the food is properly ground by the stomach acids it is ready to be transported into the small intestines.

 

Small Intestines

 

The small intestines’ function allows the nutrients to be digested and absorbed while also providing motility towards mixing and absorbing in the fed state in the body. Research studies have shown that the small intestine is a tubular organ that is responsible for the digestion and absorption of nutrients. In its fasting state, the intestine’s motility is geared towards propelling non-absorbed residue and helping make sure that the intestines are swept clean of bacteria & other residues that can infect the body. Other research studies show that the small intestines are a harsh environment for any microbial life to be in the small intestines in a short transit time and are out of the intestines to be excreted out of the body.

 

Colon

The colon’s function is to absorb excess fluid while salvaging unabsorbed nutrients via bacteria and providing permit defecation to occur so it can be excreted out through the anus. Research shows that the colon’s function is to conserve water since it is an important metabolic organ that influences the overall body’s metabolism and helps produce the activity of colonic microflora. The colon makes sure that any bile or unprocessed nutrient waste is emptied into the rectum as stool.

 

How Does The Digestive System Works?

How your digestive system works - Emma Bryce

The digestive system makes sure that food is being digested from the mouth and excreted out through the anus. The gastrointestinal (GI) tract makes sure that the digestive food is being turned into nutrients and vitamins so that way the body can absorb them and help the body function properly. The nutrients from the food also help the muscles, tissues, and cellular structure of the body to do their job as well.

The Enteric Nervous System

 

The digestive system and the central nervous system have a bidirectional connection as they pass information back and forth to make the body be functional through the enteric nervous system. Research studies have found that the enteric nervous system works with the central nervous system reflexes and the neural pathways that connect the brain and the gut to control digestive function. The enteric nervous system is composed of the following 5 groups:

  • Smooth muscle
  • Enteroendocrine cells
  • Nervous tissue cells (neurons & glia)
  • Inflammatory cells (mast cells, lymphocytes, macrophages, granulocytes)
  • Interstitial cells of Cajal

 

Interstitial Cells Of Cajal

Interstitial cells of the Cajal are non-neural elements that communicate with neurons and smooth muscles in the body. Research studies have shown that the interstitial cells of the Cajal do not form their own network as they are bipolar cells or spindle-shaped cells that are surrounding the smooth muscles. These cells provide intrinsic myoelectric frequencies that are being controlled and propagate the contractions. While the interstitial cells of the Cajal play a key part in the GI motility while also being found outside of the GI tract. Some of the 4 key functions of interstitial cells of the Cajal does are:

  • Generate a slow wave that is propagated to smooth muscle cells
  • Help mediate neurotransmission
  • Set smooth muscle membrane potential & membrane gradient
  • Involved in mechanotransduction

 

Signaling Molecules

Even though most of the signal molecules are still unclear, research shows that the signaling molecules are able to convey information and regulate cell proliferation while also providing maintenance of adult tissue. Many have believed that serotonin was the major stimulatory neurotransmitter and the main component of gut sensation, but signaling molecules can provide other key transmitters including acetylcholine, substance P, nitric oxide, and dopamine to help keep the body be functional.

 

Conclusion

All in all, the digestive system makes sure that food is being digested and excreted out. When unwanted pathogens start to enter the body and affect the gut system, chronic issues can pop up and develop over time if it is not treated. The gut system also has a bidirectional connection with the brain as both organs send out information to each other and make sure that they are doing their jobs properly. Many individuals have found ways to make sure that their gut system is operational and functioning properly as they continue on their journey to being healthier.

 

References

Cooper, Geoffrey M. “Signaling Molecules and Their Receptors.” The Cell: A Molecular Approach. 2nd Edition., U.S. National Library of Medicine, 1 Jan. 1970, www.ncbi.nlm.nih.gov/books/NBK9924/.

Fish, Elizabeth M., and Bracken Burns. “Physiology, Small Bowel.” StatPearls [Internet]., U.S. National Library of Medicine, 13 Sept. 2021, www.ncbi.nlm.nih.gov/books/NBK532263/.

Furness, John B, et al. “The Enteric Nervous System and Gastrointestinal Innervation: Integrated Local and Central Control.” Advances in Experimental Medicine and Biology, U.S. National Library of Medicine, 2014, pubmed.ncbi.nlm.nih.gov/24997029/.

Hsu, Mark, et al. “Physiology, Stomach.” StatPearls [Internet]., U.S. National Library of Medicine, 22 July 2021, www.ncbi.nlm.nih.gov/books/NBK535425/.

Kastl, Arthur J, et al. “The Structure and Function of the Human Small Intestinal Microbiota: Current Understanding and Future Directions.” Cellular and Molecular Gastroenterology and Hepatology, Elsevier, 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC6881639/.

Medical Professionals, Cleveland Clinic. “Digestive System: Function, Organs & Anatomy.” Cleveland Clinic, 9 Aug. 2021, my.clevelandclinic.org/health/body/7041-digestive-system.

Medical Professionals, Cleveland Clinic. “Stomach: Anatomy, Function, Diagram, Parts of, Structure.” Cleveland Clinic, 10 Sept. 2021, my.clevelandclinic.org/health/body/21758-stomach.

Medical Professionals, NIDDK. “Your Digestive System & How It Works.” National Institute of Diabetes and Digestive and Kidney Diseases, U.S. Department of Health and Human Services, Dec. 2017, www.niddk.nih.gov/health-information/digestive-diseases/digestive-system-how-it-works.

Moran, B J, and A A Jackson. “Function of the Human Colon.” The British Journal of Surgery, U.S. National Library of Medicine, Nov. 1992, pubmed.ncbi.nlm.nih.gov/1467882.

Disclaimer

A Look Into Mast Cell Activation Syndrome

By
Dr. Alex Jimenez
-

Introduction

The digestive system is home to the gastrointestinal (GI) tract where food is being digested and being transformed into nutrients for the body to utilize. These nutrients help the body to be functional and make sure that each of the systems in the body like the gut, the immune, the endocrine, and the musculoskeletal system need the GI tract to transport the nutrients so that they are doing their jobs properly. When unwanted pathogens and disorders start to enter the body and cause havoc to the GI tract and the body, it can lead to chronic issues over time like inflammation or even MCAS (mast cell activation syndrome). In today’s article, we will be taking a look at what mast cell activation syndrome is, its symptoms, and how to manage the symptoms of MCAS. By referring patients to qualified and skilled providers who specialized in gastroenterology services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, it may. In case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

What Is Mast Cell Activation Syndrome?

Mast cells are large (20 microns), round or ovoid immune cells that are located at the interfaces like the mucous membranes, which are the nose, the mouth, skin, gut, and the bladder. These cytoplasmic granules have “messenger” substances and are “mediators” as they are stored & quickly produced in the body. Mast cells are also found in all organs and tissues while being different in connective tissue and mucous membranes. MCAS or mast cell activation syndrome is entirely different in the body as it is often congenital and it’s an epigenetic disorder that induces somatic mutations in some mast cell progenitor cells.

 

Research studies have shown that MCAS is seen in various pathologies that include IgE-dependent allergic inflammation and other immunologic and inflammatory reactions from the body. Mast cells are often aberrant and are only a few at birth but will increase with age as instigators. MCAS is rarely serious for infants or a child but it is often resolved and can become worse during the teenage years and adulthood. Other research studies also found that MCAS is a systemic autoinflammatory disease that makes mast cells behave erratically. This is due to the overstimulation of the histamine in the immune system causing the body to have a severe allergic reaction.

 

The Symptoms & Factors

The symptoms and factors that MCAS can cause in a person vary on how severe the allergic reaction is to the body. Research studies have shown that when a person is exposed to a variety of allergens, the mast cells in the body release mediators that cause the symptoms of an allergic reaction to the body, which include itching, mucus, and inflammation. When a person has MCAS, the mediators will be released too often causing an impact on every single part of the body. Some of the symptoms that MCAS can impact the body include:

  • Constitutional- fatigue, fever, weight loss/gain
  • Central nervous system- migraines/headaches, brain fog, panic attacks, anxiety, depression, insomnia
  • Digestive system- GERD, dysphagia, chest pain, nausea, dyspepsia, bloating, abdominal pain, constipation, diarrhea
  • Immune system- poor healing
  • Salivary glands- swelling
  • Skin – flushing, hives, rashes, swelling, itching
  • Pulmonary – dyspnea, asthma, cough
  • Extremities – pain, swelling, vasospasm, numbness

An Overview of MCAS

MCAS: what is Mast Cell Activation Syndrome? - Online interview

MCAS or mast cell activation syndrome is an autoinflammatory disease that causes the mast cells in the body to be overstimulated due to allergens that have entered the body. Some of the factors and symptoms can cause unwanted problems to the body and the organ systems to develop chronic issues over time. There are ways to manage the symptoms and calm down the mast cells from being overstimulated causing allergic reactions in the individual.

How To Manage MCAS Symptoms

There are ways to manage MCAS symptoms in the body to alleviate them and calm down the overstimulated mast cells. The best way to manage MCAS symptoms is to identify and avoid triggers that can cause an allergic reaction, block receptors of mediators, and inhibit mediator production and release in the body. Research studies have found that even though there is no cure for MCAS, treatments like taking antihistamines can help individuals avoid triggers that can cause an allergy attack. Another way to help manage MCAS symptoms is by doing a food elimination for 3 weeks. What this does is that the individual has to eliminate gluten, dairy, yeast, and other food allergens that can cause a reaction to pop up.

 

Other research studies have found that consuming dietary fibers and metabolites can help lower the MCAS symptoms in the body. Dietary fibers are beneficial to the body due to being resistant to enzymatic and chemical digestion until they reach the large intestines of the gut. These dietary fibers are then fermented into SCFAs (short-chained fatty acids) and metabolites by gut bacteria. The gut bacteria need these SCFAs to flourish in the gut and protect it from unwanted pathogens like MCAS and cause chronic issues.

Conclusion

All in all, MCAS or mast cell activation syndrome is a chronic autoinflammatory disease that causes the mast cells in the body to overreact and cause an allergic reaction affecting the organs and the body itself. By eliminating the factors and causes of an allergic reaction in the body, a person can begin to heal and figure out what was causing the reaction in the first place. This will allow the body to heal from the reactions that cause the person pain and the individual will be able to live life to the fullest, knowing how to manage their symptoms.

 

References

Folkerts, Jelle, et al. “Effect of Dietary Fiber and Metabolites on Mast Cell Activation and Mast Cell-Associated Diseases.” Frontiers in Immunology, Frontiers Media S.A., 29 May 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC5992428/.

Medical Professionals, Cleveland Clinic. “Mastocytosis & Mast Cells: Symptoms & Treatment.” Cleveland Clinic, 17 Sept. 2020, my.clevelandclinic.org/health/diseases/5908-mastocytosis.

Moyer, Nancy, and Erika Klein. “Mast Cell Activation Syndrome (MCAS): Symptoms and More.” Healthline, Healthline Media, 1 Oct. 2021, www.healthline.com/health/mast-cell-activation-syndrome.

Vacheron, Nathalie, et al. “Mast Cell Activation Syndrome.” Journal of the American Association of Nurse Practitioners, U.S. National Library of Medicine, 8 Apr. 2020, pubmed.ncbi.nlm.nih.gov/32282570/.

Valent, Peter, et al. “Diagnosis, Classification and Management of Mast Cell Activation Syndromes (MCAS) in the Era of Personalized Medicine.” International Journal of Molecular Sciences, MDPI, 27 Nov. 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7731385/.

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An Overview Look At Eosinophilic Esophagitis

By
Dr. Alex Jimenez
-

Introduction

The gastrointestinal tract is part of the digestive system and its primary job is to make sure that the food is being consumed and digested to be turned into vitamins and nutrients for the body. The gastrointestinal tract also provides a protective layer in the intestinal permeability to prevent toxins and unwanted pathogens from leaking out of the gut and causing inflammation as well as other problems to the body. One of these pathogens is known as eosinophilic esophagitis and it can cause the gastrointestinal tract to be dysfunctional. In this article, we will be taking a look at what eosinophilic esophagitis is, its symptoms, and what kind of treatment to dampen its effects on the body. By referring patients to qualified and skilled providers who specialized in gastroenterology services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

What Is Eosinophilic Esophagitis?

 

In the digestive system, the esophagus’s main job is to make sure that when a person eats the food, the consumed food is traveling down to the stomach to be fully digested into nutrients for the body. When there are unwanted pathogens that start to cause damage to the esophagus, it is known as eosinophilic esophagitis. Research studies have shown that eosinophilic esophagitis is a chronic immune disease that is often characterized by a dense eosinophilic infiltrate into the esophagus. Some of the factors that can cause eosinophilic esophagitis to occur in the throat are:

  • Genes
  • Allergies
  • Mast cells
  • Acid reflux

Other research studies show that eosinophilic esophagitis causes eosinophil, a type of white blood cell to build up around the lining of the tube that connects the mouth to the esophagus. This build will cause injury or inflammation to the esophageal tissue, causing a person to have a difficult time swallowing their foods.

 

The Symptoms

Research studies have found that the pathophysiology of eosinophilic esophagitis has occurred as a result of immunogenic reactions to a variety of antigens that are most commonly found in the food that a person eats and the air they breathe. Since eosinophilic esophagitis is an immunogenic reaction, some of the symptoms can occur due to increased dietary exposure in infancy and youth all the way to adulthood. Other symptoms that can cause eosinophilic esophagitis to disrupt the esophagus can be the frequent use of antibiotics to alter the immune system and the gut flora. Other research studies have shown that the other symptoms that eosinophilic esophagitis causes in the throat and esophagus include:

  • Heartburn
  • Regurgitation
  • Chest pains
  • Trouble swallowing
  • Acute GI infections trigger chronic systemic diseases via SIBO, inflammation, autoimmunity, etc.

Another symptom that eosinophilic esophagitis causes are an increased intestinal permeability introduces larger antigens resulting in increased eos & MCs, while also causing an increase in ileal lymphoid follicles and interaction with food antigens & bacteria in the body.

An Overview On Eosinophilic Esophagitis

Eosinophilic Esophagitis - Jeffrey Alexander, M.D. - Mayo Clinic

Eosinophilic esophagitis is a chronic immune disease that causes inflammation in the lining of the throat and the esophagus (the stomach). Some of the symptoms that eosinophilic esophagitis causes are trouble swallowing, acute GI infections, and many more. The treatments that can dampen the progression of eosinophilic esophagitis include an elimination diet, immunotherapy, and medication.

How To Treat Eosinophilic Esophagitis

Since eosinophilic esophagitis is a chronic immune disease that causes inflammation in the lining of the throat and the esophagus. Research studies have found that numerous therapies for individuals that are suffering from eosinophilic esophagitis by including proton pump inhibitors, elimination diets, and topical corticosteroids that are effective and can reverse tissue fibrosis as well as decrease food impactions. Utilizing these therapeutic treatments to reverse the effects of eosinophilic esophagitis on individuals can help them recover and get their lives back together.

 

Elimination Diet

The elimination diet has been known to help individuals get their health back by eliminating certain foods that they might be sensitive to. For individuals that are suffering from eosinophilic esophagitis can use the elimination diet to help dampen the inflammatory effects that are affecting the throat and esophagus lining. Research studies have found that there 3 different approaches when it comes to treating eosinophilic esophagitis. The first approach is the elimination diet where the food allergens are removed and individuals have to consume an aminoacid-based formula to meet their nutritional needs. This will cause all the eosinophils to be eliminated and the inflammation to be resolved, while slowly re-introducing the foods one at a time to identify the individual’s food triggers.

 

The second approach is the 6-food elimination diet where individuals eliminate the 6 most common food allergens (milk, wheat, soy, egg, nuts, and fish) out of their system for 6 weeks and add them back in one at a time to identify the allergen that is causing eosinophilic esophagitis to react. The third and final approach is a skin patch test to identify the food allergen and eliminate them as part of the treatment for eosinophilic esophagitis.

 

Immunotherapy

 

Research studies have found that aeroallergens may have played a causative role in the development of eosinophilic esophagitis. For healthcare providers to utilize immunotherapy to dampen the effects of aeroallergens like pollen and dust mites that have entered the body and cause eosinophilic esophagitis to form. Individuals that are suffering from these allergens will find that immunotherapy can help them reduce their allergies and reduce the inflammation of the throat and esophagus. Another was that immunotherapy is beneficial for dampening the effects of eosinophilic esophagitis is that when it is injected into the body and downregulates the Th2 inflammation mediators that are causing the individual pain.

 

Conclusion

Therefore, eosinophilic esophagitis is a chronic immune disease that causes inflammation in the throat and esophagus lining. This immune disease is caused by allergens, genetics, and other factors that a person is suffering from, and the therapeutic treatments can help dampen the inflammatory effects. Utilizing the elimination diet and immunotherapy can help individuals find out what allergens are causing eosinophilic esophagitis to cause havoc in their bodies. Once they eliminate the source of their allergens, they can continue on their wellness journey pain-free.

 

References

Cianferoni, Antonella, and Jonathan M Spergel. “Immunotherapeutic Approaches for the Treatment of Eosinophilic Esophagitis.” Immunotherapy, U.S. National Library of Medicine, 2014, www.ncbi.nlm.nih.gov/pmc/articles/PMC4697927/.

D’Alessandro, Alessandra, et al. “Eosinophilic Esophagitis: From Pathophysiology to Treatment.” World Journal of Gastrointestinal Pathophysiology, Baishideng Publishing Group Inc, 15 Nov. 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4644879/.

Gonsalves, Nirmala P, and Seema S Aceves. “Diagnosis and Treatment of Eosinophilic Esophagitis.” The Journal of Allergy and Clinical Immunology, U.S. National Library of Medicine, Jan. 2020, pubmed.ncbi.nlm.nih.gov/31910983/.

Gonsalves, Nirmala. “Dietary Therapy for Eosinophilic Esophagitis.” Gastroenterology & Hepatology, Millennium Medical Publishing, Apr. 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4836598/.

Medical Professional, Cleveland Clinic. “ESOINOPHILIC Esophagitis: Symptoms & Treatment.” Cleveland Clinic, 10 Mar. 2021, my.clevelandclinic.org/health/diseases/14321-eosinophilic-esophagitis.

Roussel, Jordan M., and Sudha Pandit. “Eosinophilic Esophagitis.” StatPearls [Internet]., U.S. National Library of Medicine, 14 Aug. 2021, www.ncbi.nlm.nih.gov/books/NBK459297/.

Staff, Mayo Clinic. “Eosinophilic Esophagitis.” Mayo Clinic, Mayo Foundation for Medical Education and Research, 23 Sept. 2020, www.mayoclinic.org/diseases-conditions/eosinophilic-esophagitis/symptoms-causes/syc-20372197.

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An Overview Of Nonalcoholic Fatty Liver Disease

By
Dr. Alex Jimenez
-

Introduction

The digestive system is home to many of the organs that help digest food into vitamins and nutrients and has a bidirectional with the central nervous system. The organs that consist in the digestive system include the stomach, the intestines (both large and small), and the liver to name a few. When there are unwanted factors and pathogens that enter through the mouth and into the digestive system can cause problems and unwanted symptoms like inflammation, leaky gut, and nonalcoholic fatty liver disease (NAFLD) pop up over time causing a person to be in pain. In this article, we will be taking a look at what the liver does in the body, what is NAFLD and its symptoms, as well as some treatments to prevent NAFLD’s effects on the body from rising. By referring patients to qualified and skilled providers who specialized in gastroenterology services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

What Does The Liver Do?

 

About the size of a football, the liver is a reddish-brown wedge-shaped organ that has many functions that help the body stay functional. Research studies show that the liver has many physiological processes like macronutrient metabolism, blood volume regulation, immune support, helps control growth signaling pathways for the endocrine system, and many more. Located in the upper right-hand portion of the body and on top of the stomach, the liver is an essential organ that provides proteins and hormones that the other organs need in the body. Other research studies have shown that some of the jobs that the liver does for the body include:

  • Stores glycogen and vitamins for the body to use later
  • Make bile fluid to help the body digest food
  • Cleans toxins out of the blood
  • Metabolizes proteins, carbohydrates, and fats 
  • Produces substances to help with blood clots

 

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

Stem cells* or HCTP (human cellular tissue products) are used in both affiliated clinics and distribution organizations as a form of regenerative cellular treatments to help boost the body’s own natural healing process. Some of the beneficial properties that HCTP provides to the body is that it helps repair and regenerate damaged cells, diseased organs, and tissues back to their original state and function in the body. With much more upcoming research on the benefits that HCTP provides to the body, many individuals can begin to feel better and continue on their wellness journey pain-free.

What Is NAFLD?

 

NAFLD or nonalcoholic fatty liver disease is a range of liver conditions that affect the liver. Research studies have shown that NAFLD has several phases of progressions in the body since it has a benign course as a silent liver disease due to the presence of hepatic injury with inflammation. Since 3-6 million Americans with viral hepatitis don’t know they are infected with NAFLD, there could be many factors that can lead to the progression of NAFLD. In 2004, the National Institute of Health estimated the annual costs in the US of chronic liver disease and cirrhosis is $1.6 billion. However, the most recent estimates of the population with liver disease in the US range from 15 to 30 million, indicating that the annual cost may range from $5 to $10 billion. Other studies have found that NAFLD is a growing pandemic worldwide due to obesity and insulin resistance that can lead the liver to accumulate triglycerides and free fatty acids in the body.

 

The Symptoms

Research studies show that in most cases fatty liver diseases don’t cause any serious problems or prevent the liver from functioning properly unless the person has it and the disease gets worse over time as it progresses in three stages. The first stage is known as steatohepatitis, where the liver becomes inflamed causing tissue damage. The second stage is fibrosis, where scar tissues begin to form on the damaged areas of the liver. And finally, the third stage is cirrhosis, where there is extensive scar tissue replacing the healthy liver tissues. Other symptoms that NAFLD can cause in the body include:

 

How To Treat Liver Disease?

There are ways to prevent liver disease from progressing further in the liver and can be reversed when there is a sign of early liver damage. The amazing thing about the liver is that it has the ability to repair itself and utilize different treatments to prevent progressive liver disease from causing further damage. Research studies have shown that lifestyle interventions, pharmacological therapy, exercise, and caloric restrictions are beneficial to treat liver disease.

 

Exercise

Doing any sort of exercise is beneficial not only for the body but also for the liver. Research studies show that when a person exercises, there will be an increase in fatty acid oxidation, a decrease in fatty acid synthesis, and mitochondrial and hepatocellular damage will be prevented and reduced. Physical exercises can improve fatty liver disease and help individuals lose weight, lower their insulin and reduce the excess free fatty acids. Another beneficial property that physical activity can provide to individuals is that it can improve their moods and stop neurological disorders from progressing as well. Other research studies have shown that with the combination of calories restriction, physical activity can effectively decrease the intrahepatic lipid component.

 

Conclusion

All in all, the liver is part of the digestive system where it sends out nutrients and vitamins to the entire body. When there are unwanted pathogens that enter through the mouth and disrupt the digestive system, it can cause chronic symptoms like inflammation and nonalcoholic fatty liver disease and damage the liver. Since NAFLD is a chronic progressive disease, by incorporating treatments like eating healthy, exercising, and taking supplements can help people be pain-free on their wellness journey.

 

References

Beaton, Melanie D. “Current Treatment Options for Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis.” Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie, Pulsus Group Inc, June 2012, www.ncbi.nlm.nih.gov/pmc/articles/PMC3378283/.

Benedict, Mark, and Xuchen Zhang. “Non-Alcoholic Fatty Liver Disease: An Expanded Review.” World Journal of Hepatology, Baishideng Publishing Group Inc, 8 June 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5468341/.

Berzigotti, Annalisa, et al. “Physical Activity and Liver Diseases.” Hepatology (Baltimore, Md.), U.S. National Library of Medicine, Mar. 2016, pubmed.ncbi.nlm.nih.gov/26313307/.

Kudaravalli, Pujitha, and Savio John. “Nonalcoholic Fatty Liver.” StatPearls [Internet]., U.S. National Library of Medicine, 19 July 2021, www.ncbi.nlm.nih.gov/books/NBK541033/.

Medical Professionals, Cleveland Clinic. “Fatty Liver Disease: Risk Factors, Symptoms, Types & Prevention.” Cleveland Clinic, 31 July 2020, my.clevelandclinic.org/health/diseases/15831-fatty-liver-disease.

Medical Professionals, Cleveland Clinic. “Liver: What It Does, Disorders & Symptoms, Staying Healthy.” Cleveland Clinic, 22 Feb. 2021, my.clevelandclinic.org/health/articles/21481-liver.

Trefts, Elijah, et al. “The Liver.” Current Biology: CB, U.S. National Library of Medicine, 6 Nov. 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5897118/.

van der Windt, Dirk J, et al. “The Effects of Physical Exercise on Fatty Liver Disease.” Gene Expression, Cognizant Communication Corporation, 18 May 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC5954622.

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An Overview On Different Factors Affecting Gut-Brain Axis | Part 2

By
Dr. Alex Jimenez
-

Introduction

The gut and the brain have two different jobs that do different functions in the body but, have a bidirectional communication with each other. The brain is part of the central nervous system that sends out neuron signals all throughout the entire body. These neuron signals make sure that everything is working properly, from the heart beating to blood pressure being regulated. The gut is part of the digestive system and it makes sure that food is being digested properly, while the beneficial good bacteria is protecting the gut from harmful pathogens. When unwanted pathogens start to affect either the brain, the gut, or both, it can cause problems to the body making it dysfunctional and causing the individual unwanted pain. In this 2 part series, we will be taking a look at the different factors that can affect the gut-brain axis. Part 1 took a look at what the gut-brain axis is and how does it function in the body. By referring patients to qualified and skilled providers who specialized in gastroenterology services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

The Gut-Brain Connection

 

The gut-brain connection provides a bidirectional connection to both the brain and the gut. Both of these organs continuously send each other signals back and forth in order to make sure that the body is functioning properly while also doing their jobs as well. Research studies show that the gut-brain connection is also known as the enteric nervous system and what it does is that it’s a network of nerves, neurons, and neurotransmitters that extends all over the entire digestive tract. The enteric nervous system is also referred to as a “second brain”, which is the gut as it is in constant communication to the brain and plays a major key role in diseases and mental health for individuals.

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

Stem cells* or HCTP (human cellular tissue products) are a form of regenerative cellular treatments that help boost the body’s own natural healing process. HCTP has been used in both international and nationally affiliated clinics and distribution organizations by repairing and regenerating damaged cells, diseased tissues, and organs back to their original state and function in the body. With more upcoming research about the beneficial properties of HCTP, many individuals can get their lives back together pain-free and without chronic issues affecting them.

The Factors That Affect The Gut-Brain

There are many factors that can affect both the gut and the brain as the body does encounter many pathogens that can cause a person to be in pain. Studies have found that gut microbiota has been known to support tight junction integrity and when dysbiosis and increased intestinal permeability can cause dysfunction to the brain. The same goes for the brain when the neuron signals are being disrupted by unwanted pathogens that travel from the brain to the gut. Other factors that can affect the gut-brain axis include:

 

Visceral Pain

 

Research shows that visceral pain is described as pain originating from the internal organs of the body and can cause the development of neurological behavioral disorders. Visceral pain can also cause gastrointestinal disorders as it causes damage to the thorax and abdomen while also making maladaptive changes to alter the brain structure and function. Other research studies have found that visceral pain is a complex and heterogeneous disorder that involves the spinal cord, a higher order of the brain structure, and manipulates the gut microbiota. Some of the mechanical features that visceral pain causes gastrointestinal pain and discomfort that can cause painful stimuli to the brain.

 

Stress

Stress can be both beneficial and harmful to the body, especially to the gut and the brain. When stress is in its acute form, it can help give the body a “fight or flight response” effect that gives the body a little boost of energy. However, when stress is in its chronic state can cause damage to the brain and gut as it can become harmful over time if it is not treated. Studies show that the importance of the gut-brain axis in regulating stress responses has been long appreciated as it can impact mental and gut health. When stress starts to affect both the gut and the brain, the neuron signals will get disrupted and can kill the neuron’s signals and replaced them with new ones to cause havoc on the gut-brain axis. Other studies have found that when a person is under chronic stress, gut infections and inflammation can cause an increase in high-co-morbidity of anxiety and depression disorders in people.

 

Inflammation

 

Just like stress, inflammation can be both beneficial and harmful to the body and the brain-gut connection. The beneficial factor of inflammation in its acute form is that it can naturally heal an injury by making the affected area swell up, red, and hot to the touch which can last for a few minutes to an hour, depending on the injury. Studies have shown that the gut-brain connection has molecular and cellular mechanisms that regulate inflammatory responses to the body. However, just like chronic stress, when the body has chronic inflammation can cause havoc on the gut by attaching itself to the intestinal permeability and causing the immune system to attack the permeability causing a leaky gut. For the brain, inflammation can attach to the neuron signals and travel up to the brain to cause havoc on the blood-brain barrier and develop neuroinflammation.

 

Conclusion

All in all, the gut-brain connection has a wonderful bidirectional connection that makes sure that not only the body is staying functional, but also for each of the organs to do their jobs properly as well. When unwanted pathogens start to affect the brain-gut connection, it can cause numerous problems to the body with chronic inflammation, chronic stress, and many other issues that can cause a person to be in pain. Utilizing a healthy diet filled with nutritional food, getting up to do some sort of physical exercise, and making small changes to a lifestyle habit can dampen the effects of chronic issues that are affecting the body and provide the individual with a pain-free lifestyle.

 

References

Agirman, Gullistan, et al. “Signaling Inflammation across the Gut-Brain Axis.” Science (New York, N.Y.), U.S. National Library of Medicine, 25 Nov. 2021, pubmed.ncbi.nlm.nih.gov/34822299/.

Appleton, Jeremy. “The Gut-Brain Axis: Influence of Microbiota on Mood and Mental Health.” Integrative Medicine (Encinitas, Calif.), InnoVision Health Media Inc., Aug. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6469458/.

Bear, Tracey, et al. “The Microbiome-Gut-Brain Axis and Resilience to Developing Anxiety or Depression under Stress.” Microorganisms, MDPI, 31 Mar. 2021, www.ncbi.nlm.nih.gov/pmc/articles/PMC8065970/.

Foster, Jane A, et al. “Stress & the Gut-Brain Axis: Regulation by the Microbiome.” Neurobiology of Stress, U.S. National Library of Medicine, 19 Mar. 2017, pubmed.ncbi.nlm.nih.gov/29276734/.

Medical Professionals, Cleveland Clinic. “Gut-Brain Connection: What It Is, Behavioral Treatments.” Cleveland Clinic, 3 Dec. 2020, my.clevelandclinic.org/health/treatments/16358-gut-brain-connection.

Moloney, Rachel D, et al. “Stress and the Microbiota-Gut-Brain Axis in Visceral Pain: Relevance to Irritable Bowel Syndrome.” CNS Neuroscience & Therapeutics, John Wiley and Sons Inc., Feb. 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC6492884/.

Pusceddu, Matteo M, and Melanie G Gareau. “Visceral Pain: Gut Microbiota, a New Hope? – Journal of Biomedical Science.” BioMed Central, BioMed Central, 11 Oct. 2018, jbiomedsci.biomedcentral.com/articles/10.1186/s12929-018-0476-7.

Disclaimer

A Focused Look On The Gut-Brain Axis | Part 1

By
Dr. Alex Jimenez
-

Introduction

The gut system makes sure that the good bacteria is helping the gut by digesting the consumed food into nutrients for the body and keeping the unwanted pathogens from causing chronic inflammation to the intestinal permeability barrier. The gut has a pretty good bidirectional connection to the brain as they send signals back and forth to each other while making sure that the body is functional and that everything is working properly. In this 2 part series, we will be taking at what is the gut-brain axis and how does it function in the body. Part 2 will be taking at the different factors that can affect the gut-brain axis. By referring patients to qualified and skilled providers who specialized in gastroenterology services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

What Is The Gut-Brain Axis?

Also known as the “gut feeling” in the body, the gut-brain axis as research shows that the gut-brain axis has consisted of bidirectional communication between the central and enteric nervous system. The brain sends signals to the gut to make sure that everything is working properly and vice versa. Other studies have also shown that gut microbes actually communicate to the central nervous system through at least 3 parallel interactive channels that include the nervous, endocrine, and immune signaling mechanisms that make the body functional. When the gut or the brain is being dysfunctional, it can cause many problems in the body and can be developed into chronic issues that will happen over time.

 

The “Forgotten Organ”

 

Research studies have shown that the intestinal microflora is a positive health asset as it is crucially influenced by the normal structural and fundamental development of the mucosal immune system. What this means is that the bacteria density increases in the jejunum/ileum from the stomach and duodenum. In the large intestine, there are colon-residing bacteria that achieve the highest cell densities recorded for any ecosystem, whether it is the gut or the brain. Other studies have shown that the resident microorganisms in the body establish in their respective colonies while performing a variety of vital functions in the body by exerting a range of protective, structural, and metabolic effects on the intestinal mucosa.

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

Stem cells* or HCTP (human cellular tissue products) are a form of regenerative medicine that both international and nationally affiliated clinics and distribution organizations use to help boost the body’s own natural healing process. HCTP has beneficial properties by repairing cells, diseased organs, and tissues back to their original state and function in the body. With more and upcoming research about the beneficial properties of HCTP, many individuals with either neurological disorders or gut issues can be provided with relief.

Diversity Is The Key For Gut Health

Having diversity in the body is important for gut health as it helps shape a person in the world. The alpha diversity is a measure of the compositional complexity of a community within a site as it increases with the number of present species and with the evenness of their relative abundances in the gut. While the beta diversity looks at the differences in the taxonomic abundance profiles from different samples as presence-absence data are often used to identify which species are shared by samples and which are not. Research studies have shown that the abundance of specific bacterial genera can be significantly predicted by a person’s personality traits. The gut needs bacteria to thrive on the inside as it helps protect the gut from toxins and pathogens that are trying to disturb the microbiota. Other studies have found that when nutritional foods enter the GI microbial ecosystem, it provides macro-and micro-nutrients to the gut microbial as it helps the gut to be diverse, stable, and healthy.

 

Neurodevelopment & The Gut

Studies have found that the bidirectional communication between the gut and brain is established due to the colonization patterns and cognition at the early stages of a person’s life. The brain is part of the central nervous system that makes sure that the information from the gut is being transferred back to the brain. Other studies have been shown that the production of metabolites can help influence the central nervous system and enhanced the integrity of the intestinal epithelial layer through SCFAs (short-chain fatty acids). The SCFAs traveling back and forth through the gut and the brain allows the bacterial strains will decrease the permeability of the blood-brain barrier.

 

Microbiota Regulates Anxiety

 

The gut microbiota actually helps to regulate the body and brain function in the body as it can help monitor the neuron signals that are providing the sensations and emotional signals in the body. Studies have found that when the intestinal flora modulates the gut-brain axis communication, it involves the nervous system, immune system, and endocrine system to make it functional. When the intestinal flora is being affected by pathogens though, it can cause a series of changes in the physical and mental symptoms to occur like anxiety. This is due to any inflammation and dysbiosis that has been affecting the gut, as research studies show that any chronic inflammation has been linked to mental illnesses like anxiety and depression. When a person has inflammation in the gut, it can cause them pain and suffering as they don’t really know what is going on. By establishing antioxidant-riched foods into the gut system, the inflammation can be dampened and even improve brain health.

 

Conclusion

All in all, the gut-brain axis has a bidirectional connection that makes sure that the gut and the brain are communicating with each other as well as doing their jobs properly. With this bidirectional communication, the gut makes sure that the signaling mechanisms are working properly and that unwanted pathogens are not entering each of the systems. When this happens, both the gut and the brain will begin to be dysfunctional and cause chronic issues to be developed. Utilizing anti-inflammatory foods and exercises can dampen these effects and the individual can begin their life pain-free.

 

References

Carabotti, Marilia, et al. “The Gut-Brain Axis: Interactions between Enteric Microbiota, Central and Enteric Nervous Systems.” Annals of Gastroenterology, Hellenic Society of Gastroenterology, 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4367209/.

Clapp, Megan, et al. “Gut Microbiota’s Effect on Mental Health: The Gut-Brain Axis.” Clinics and Practice, PAGEPress Scientific Publications, Pavia, Italy, 15 Sept. 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5641835/.

Heiman, Mark L, and Frank L Greenway. “A Healthy Gastrointestinal Microbiome Is Dependent on Dietary Diversity.” Molecular Metabolism, Elsevier, 5 Mar. 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC4837298/.

Johnson, Katerina V-A. “Gut Microbiome Composition and Diversity Are Related to Human Personality Traits.” Human Microbiome Journal, Elsevier Ltd, Mar. 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC8336012/.

Martin, Clair R, et al. “The Brain-Gut-Microbiome Axis.” Cellular and Molecular Gastroenterology and Hepatology, Elsevier, 12 Apr. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6047317/.

O’Hara, Ann M, and Fergus Shanahan. “The Gut Flora as a Forgotten Organ.” EMBO Reports, U.S. National Library of Medicine, July 2006, www.ncbi.nlm.nih.gov/pmc/articles/PMC1500832/.

Rothenberg, Sarah E, et al. “Neurodevelopment Correlates with Gut Microbiota in a Cross-Sectional Analysis of Children at 3 Years of Age in Rural China.” Scientific Reports, Nature Publishing Group UK, 1 Apr. 2021, www.ncbi.nlm.nih.gov/pmc/articles/PMC8016964/.

Seo, Dong-Oh, and David M Holtzman. “Gut Microbiota: From the Forgotten Organ to a Potential Key Player in the Pathology of Alzheimer’s Disease.” The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, Oxford University Press, 18 June 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7302187/.

Warner, Barbara B. “The Contribution of the Gut Microbiome to Neurodevelopment and Neuropsychiatric Disorders.” Pediatric Research, U.S. National Library of Medicine, 25 Sept. 2018, pubmed.ncbi.nlm.nih.gov/30283047/.

Yang, Beibei, et al. “Effects of Regulating Intestinal Microbiota on Anxiety Symptoms: A Systematic Review.” General Psychiatry, BMJ Publishing Group, 17 May 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6551444/.

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An Overview Of Beneficial Ways To Improve GI | Part 2

By
Dr. Alex Jimenez
-

Introduction

The gut system’s main function is to digest food to be turned into nutrients in the body and excrete the waste out of the body. The gastrointestinal tract or GI tract makes sure that the beneficial bacteria are keeping the gut happy and healthy while the intestinal permeability is keeping the toxins and unwanted pathogens out. However, when pathogens do enter the gut can start to disrupt the intestinal wall permeability, it can cause gut inflammation and other chronic illnesses to pop up over the gut and cause a person to be in pain. In this 2 part series, we will be taking a look at ways to keep a healthy gut intact. In Part 1, we took a look at what is the GI tract and its role on the gut. By referring patients to qualified and skilled providers who specialized in gastroenterology services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

The Roles Of GI Microbiota

 

Since the gut system is home to the GI tract, research studies have shown that the GI microbiota plays a role in the body’s physiology, metabolism, and nutrition. The gut makes sure that the body is getting the right amount of nutrients while producing beneficial gut flora to keep everything working. Other research studies have found that gut microbiota has been associated with gastrointestinal diseases like IBD (inflammatory bowel disease), SIBO, metabolic disorders, and neurological disorders just to name a few. The gut is connected to the entire body as it plays a functional role in a person’s health as it is one of the main sources where inflammation seems to target the most.

 

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

Stem cells* or HCTP (human cellular tissue products) have been used in both international and nationally affiliated clinics and distribution organizations as a form of regenerative therapy treatment. HCTP helps the body boost its own natural healing process by regenerating and repairing damaged cells, diseased tissues, and organs back to their original functioning state. With more and upcoming research discussing the beneficial properties of HCTP, many individuals will begin to feel better from any chronic illnesses that they have encountered and start on their wellness journey.

Ways To Improve GI Microbiota

There are many ways to help improve the GI microbiota in the body. Many individuals will often find ways to improve their lifestyles by making small changes in their daily routines, changing their eating habits, exercising more, and moving around to make their lives better. Research studies have shown that in the gut microbiota the bacteria, fungi, and viruses actually live in a harmonic dynamic equilibrium together in the intestinal tract. The gut needs them in order for the microbiome to thrive and produce good bacteria in order for the gut system to be functional. Other research studies have found that when there is a right balance of microorganisms in the gut, the microbion will improve the body’s mental and physical health as well as other microbiomes.

 

Stop Taking Antibiotic

Even though antibiotics are beneficial to the body by getting rid of viruses and bacteria, they can cause harm to the gut microbiota. Research studies have shown that when individuals use antibiotics in their system will cause negative effects on their gut microbiota. What antibiotics do to the gut is that they can reduce the bacterial species diversity, cause an altered metabolic activity, and caused a recurrence of viral infections to the gut. Other studies have found that antibiotics can cause microbial dysbiosis and cause the disruption of the gut microbiota. When individuals are taking an excessive amount of antibiotics for chronic illnesses, it can destroy the gut flora and cause even more illnesses to rise, but taking antibiotics in small amounts will get rid of the virus and not harm the GI microbiota.

 

Berberine

 

Research studies have shown that when individuals that are suffering from obesity and diabetes due to gut microbial dysbiosis should use berberine. Berberine has been used to dampen the effects of inflammation and lower glucose levels in the body. Other studies have found that berberine has antioxidants and anti-inflammatory properties that can help not only the gut but also provide neuro-protective and cardiovascular-protective effects on the brain and heart.

 

Probiotics

 

Known as “living microorganisms”, probiotics are beneficial to the gut as they help get rid of the bad bacteria and feed the good bacteria of the gut. Studies have shown that probiotics contain Lactobacilli, which can help manipulate the intestinal microbial, suppress the pathogens that harm the gut, and stimulate the epithelial cells while fortifying the intestinal barrier. Probiotics are essential to gut health as they are part of the 5R program, which helps reset the gut and helps dampen the effects of inflammation. Other research studies show that the primary job that probiotics provide is that they provide a healthy balance to the body when the bad bacteria start to increase. Probiotics will fight them off and restore balance to the gut and the body.

 

Conclusion

All in all, finding ways to make sure that the gut stays healthy is by making small changes in the way a person eats, their lifestyles, and exercising can not only help the gut stay healthy but the body as well. When there is inflammation in the gut, it can cause a person to feel bad and if it is not treated right away can develop into chronic inflammation over time. By taking probiotics, eliminating foods that may cause a person inflammation, and eating antioxidant-rich foods can dampen the effects of inflammation to the gut and restore the GI microbiota.

 

References

Gagliardi, Antonella, et al. “Rebuilding the Gut Microbiota Ecosystem.” International Journal of Environmental Research and Public Health, MDPI, 7 Aug. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6121872/.

Guinane, Caitriona M, and Paul D Cotter. “Role of the Gut Microbiota in Health and Chronic Gastrointestinal Disease: Understanding a Hidden Metabolic Organ.” Therapeutic Advances in Gastroenterology, SAGE Publications, July 2013, www.ncbi.nlm.nih.gov/pmc/articles/PMC3667473.

Hemarajata, Peera, and James Versalovic. “Effects of Probiotics on Gut Microbiota: Mechanisms of Intestinal Immunomodulation and Neuromodulation.” Therapeutic Advances in Gastroenterology, SAGE Publications, Jan. 2013, www.ncbi.nlm.nih.gov/pmc/articles/PMC3539293/.

Jandhyala, Sai Manasa, et al. “Role of the Normal Gut Microbiota.” World Journal of Gastroenterology, Baishideng Publishing Group Inc, 7 Aug. 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4528021/.

Leonard, Jayne. “10 Research-Backed Ways to Improve Gut Health.” Medical News Today, MediLexicon International, 28 May 2019, www.medicalnewstoday.com/articles/325293.

Medical Professionals, Cleveland Clinic. “Probiotics: What Is It, Benefits, Side Effects, Food & Types.” Cleveland Clinic, 9 Mar. 2020, my.clevelandclinic.org/health/articles/14598-probiotics.

Ramirez, Jaime, et al. “Antibiotics as Major Disruptors of Gut Microbiota.” Frontiers in Cellular and Infection Microbiology, Frontiers Media S.A., 24 Nov. 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7732679/.

Zhang, Lichao, et al. “Effects of Berberine on the Gastrointestinal Microbiota.” Frontiers in Cellular and Infection Microbiology, Frontiers Media S.A., 19 Feb. 2021, www.ncbi.nlm.nih.gov/pmc/articles/PMC7933196.

Zhang, Sheng, and De-Chang Chen. “Facing a New Challenge: The Adverse Effects of Antibiotics on Gut Microbiota and Host Immunity.” Chinese Medical Journal, Wolters Kluwer Health, 20 May 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6511407/.

Zhang, Yifei, et al. “Gut Microbiome-Related Effects of Berberine and Probiotics on Type 2 Diabetes (the Premote Study).” Nature News, Nature Publishing Group, 6 Oct. 2020, www.nature.com/articles/s41467-020-18414-8.

Disclaimer

An Insightful Overview Of The GI | Part 1

By
Dr. Alex Jimenez
-

Introduction

The gut is home to many bacterias that help out the body by digesting the food that a person eats, and excretes the waste out of the body. The gut system also makes sure that each of the organs is doing its job and sending the information to the brain that everything is working properly. When there are unwanted pathogens that enter the body and start to mess with the gut and the GI tract, it can cause chronic inflammation and unwanted gastrointestinal problems that can disrupt the permeability of the gut. In this 2 part series, we will be taking a look at what is the GI tract and its role in the gut. In Part 2, we will discuss what are ways to keep a healthy gut intact. By referring patients to qualified and skilled providers who specialized in gastroenterology services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Alex Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

What Is The GI Tract Function?

In the gut system, the gastrointestinal (GI) tract is part of that system along with the pancreas, the liver, the stomach, the small and large intestines, the mouth, the rectum, and the anus. Research studies have shown that the primary function of the GI tract is to digest and absorb the ingested nutrients and to exert waste products out. When a person eats nutritional food that is insoluble and can’t be digested, the GI tract can turn these insoluble nutrients into soluble nutrients that can permit the body to absorb them in the mucosal epithelium of the gut. Other studies have also shown that when the digestive system breaks down proteins, fats, and carbohydrates, the body can absorb these nutrients and even used them for energy, growth, and cell repair for the body.

 

Digestion and Absorption

The digestion and absorption from the GI tract help break down complex foods into basic constituents by dividing the macronutrients into basic units and releasing the micronutrients from the food matrix. The GI tract lets the body selectively absorb the nutrients while also transforming them and the phytonutrients while maintaining a barrier against the entry of unwanted particles that enter the body. When there are nutrients that are not absorbed uniformly, there are specific locations where the available transporters or necessary processes are found in the body. Research shows that digestion is highly important for the body because it needs the nutrients from the food and liquids that a person eats and drinks in order to stay healthy. Not only that but the appropriate timing and sequence is also
important as the bowel transit time can adversely affect the GI tract.

 

When the transporters and enzyme capacity in the body becomes overwhelmed, it can reduce the effective benefits of dietary nutrients for the body to function properly and causes the GI tract to developed unwanted gut disorders. Another factor to take into consideration is that the nutrients can also be produced by colonic bacteria and may have a limited bioavailability that may be beneficial to colonocytes and microbes in the gut system.

Enteroendocrine Cells

The enteroendocrine cells, as studies have found, are the first level of integrating information from the gut lumen and releasing signaling molecules that activate the nerve fibers in the body. The enteroendocrine cells are part of the gut system and the endocrine system that helps release hormones into the bloodstream and travel all throughout the body. Research studies have found that as part of “the largest endocrine organ” or the gut, the enteroendocrine cells play an important role in the lower GI tract as it acts as sensors to the luminal contents by exerting waste out the GI tract like gastric emptying.

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

Stem cells* or HCTP (human cellular tissue products) are part of regenerative therapy treatments that both international and nationally affiliated clinics and distribution organizations use to help individuals dampen the effects of chronic disorders and help boost the body’s own natural healing process. HCTP has beneficial properties that help repair and regenerate damaged cells, tissues, and organs back to their original functional state in the body. As more upcoming research discusses the beneficial properties of HCTP, many individuals can begin their wellness journey pain-free and without chronic pain.

 

Is It Interface Or Barrier In The Gut?

 

The permeability and barrier function of the gut is represented as one of the most important interfaces between a person and the external environment. However, by not imagining that the barrier function as a system to keep things out from causing gut problems, but as a sophisticated system that communicates with and allows selectively entry of, certain contents from the gut lumen into the body. The gut barrier requires a tightly controlled but thin barrier of tissues and secretions intentionally designed for close proximity to the gut lumen. This will permit the absorption of available nutrients and physiological interaction with trillions of non-human microbes and their metabolites and signals, but also creates a vulnerability to those same microbes, toxins, and immunologically reactive components from the gut lumen.

 

Tight Junction

Research studies have found that the tight junction in the gut forms a continuous intercellular barrier that is between the epithelial cells. Since many proteins are actually localized in the tight junction, they become critical barrier proteins that make sure that no toxins or unwanted pathogens leaked out. When inflammation starts to attach itself to the tight junction barrier, the immune system will attack the tight junction and release the toxins and molecules out of the gut permeability causing a leaky gut.

 

Paneth Cells

 

Paneth cells are found only in the small intestines and help migrate into the crypt after the differentiation of HCTP and are long-lived compared to absorptive cells. Research has found that paneth cells play an integral role in maintaining intestinal homeostasis and modulating the physiology of the small intestine. The paneth cells actually secrete antimicrobial peptides (AMPs) and immunomodulating proteins into the gut lumen while also providing the function of regulating HCTP activity to help repair the intestinal epithelial cells from injury and intestinal inflammation.

 

Conclusion

All in all, the gut system is home to the gastrointestinal tract which makes sure that any food or liquids that are consumed are being digested for the nutrients for the body and excrete the waste out. When there are disruptors or pathogens that enter the gut and cause inflammation to the intestinal permeability can cause many gut issues that can cause a person pain. The only way to dampen the effects of inflammation is through neutraceuticals that can lower the inflammatory cytokines and consuming food that contains pre and probiotics to help with producing the good bacteria in the gut. When individuals find ways to lower gut inflammation, then they can continue to be pain-free from inflammation.

 

References

Anderson, James M, and Christina M Van Itallie. “Physiology and Function of the Tight Junction.” Cold Spring Harbor Perspectives in Biology, Cold Spring Harbor Laboratory Press, Aug. 2009, www.ncbi.nlm.nih.gov/pmc/articles/PMC2742087/.

Gunawardene, Ashok R, et al. “Classification and Functions of Enteroendocrine Cells of the Lower Gastrointestinal Tract.” International Journal of Experimental Pathology, Blackwell Publishing Ltd, Aug. 2011, www.ncbi.nlm.nih.gov/pmc/articles/PMC3144510/.

Hornbuckle, William E., et al. “Gastrointestinal Function.” Clinical Biochemistry of Domestic Animals, U.S. National Library of Medicine, 22 Oct. 2008, www.ncbi.nlm.nih.gov/pmc/articles/PMC7173558.

Lueschow, Shiloh R, and Steven J McElroy. “The Paneth Cell: The Curator and Defender of the Immature Small Intestine.” Frontiers in Immunology, Frontiers Media S.A., 3 Apr. 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7145889/.

Medical Professionals, Cleveland Clinic. “Digestive System: Function, Organs & Anatomy.” Cleveland Clinic, 9 Aug. 2021, my.clevelandclinic.org/health/body/7041-digestive-system.

Medical Professionals, NIDDK. “Your Digestive System & How It Works.” National Institute of Diabetes and Digestive and Kidney Diseases, U.S. Department of Health and Human Services, Dec. 2017, www.niddk.nih.gov/health-information/digestive-diseases/digestive-system-how-it-works.

Sternini, Catia, et al. “Enteroendocrine Cells: A Site of ‘Taste’ in Gastrointestinal Chemosensing.” Current Opinion in Endocrinology, Diabetes, and Obesity, U.S. National Library of Medicine, Feb. 2008, www.ncbi.nlm.nih.gov/pmc/articles/PMC2943060/.

Disclaimer

Spondylitis Anti-Inflammation Diet

By
Dr. Alex Jimenez
-

Spondylitis Anti-Inflammation Diet: Individuals who have a chronic back pain condition can be recommended to have two or more vertebrae fused to correct the problem/s and alleviate the pain. However, a form of inflammatory spinal arthritis can cause the vertebrae to fuse by themselves, known as ankylosing spondylitis. One recommended way to bring pain relief is by eating an anti-inflammatory diet. Studies have shown that a low-inflammatory diet can help improve spondylitis symptoms.

Spondylitis Anti-Inflammation Diet

Spondylitis Anti-Inflammation Diet

Ankylosing spondylitis is a progressive inflammatory disease that primarily affects the spine; however, individual symptoms vary. Symptoms include stiffness and pain in the neck, hips, low back, and fatigue. There is no definite pattern meaning:

  • Symptoms can improve.
  • Symptoms can worsen or flare up.
  • Symptoms can stop for a period of time.

Women are affected more often than men with no known cause. There is no cure for ankylosing spondylitis, but treatments and self-care can slow down the disease’s progression and help manage symptoms.

Diet and Inflammation

Diet is not the root cause of inflammatory disease, but eating inflammation-causing foods can worsen symptoms. Reducing inflammation can help alleviate pain.

  • Eliminating foods that cause or increase inflammation is recommended to help the body become stronger and manage symptoms.
  • Another way is to incorporate spondylitis anti-inflammation foods.
  • Functional medicine practitioners can help guide individuals on maximizing healthy nutrition and using it to reduce pain and symptoms.
  • If an individual has a genetic predisposition, their diet can be crucial to calm down the symptoms and help turn the autoimmune disease around.

A spondylitis anti-inflammation diet should be rich in vegetables, fruit, whole grains, and omega-3 fatty acids. Evidence shows that a diet low in starches can lead to less ankylosing spondylitis activity. Low-starch can also help limit the presence of Klebsiella pneumoniae, a bacteria that feeds on starch and is a known trigger for the onset and development of ankylosing spondylitis.

Foods To Eat

Leafy greens

  • These include spinach, kale, Swiss chard, and collard greens containing magnesium and polyphenols that reduce inflammation.
  • These can be raw or cooked with garlic and olive oil added to maximize benefits.

Cruciferous vegetables

  • These contain sulforaphane, an antioxidant that includes broccoli cauliflower and can be eaten raw or cooked, roasted with olive oil, sauteed, and stir-fried.

Allium Vegetables

  • These contain sulfuric compounds and quercetin, a flavonoid that helps reduce inflammation.
  • These include red and yellow onions, leeks, garlic, and shallots.
  • They can be eaten raw or cooked in salads, stir-frys, and sandwiches.

Berries

  • These contain anthocyanin, an antioxidant flavonoid, and other antioxidants and polyphenols that help with inflammation.
  • These include strawberries, raspberries, blueberries, blackberries and can be eaten raw, in smoothies, in salads, with oatmeal, or mixed in unsweetened yogurt.

Fruits

  • Certain fruits contain quercetin and polyphenols to help with inflammation.
  • These include apples, cherries, oranges.

Healthy oils

  • Contain oleocanthal which acts similar to nonsteroidal anti-inflammatory medications and contains various antioxidants.
  • These include olive oil for low heat cooking and avocado oil for high heat cooking to replace butter and margarine.
  • It can be served in dressings and drizzled on foods.

Nuts and seeds

  • These contain alpha-linolenic acid, which is a type of omega-3 fatty acid.
  • Examples include walnuts, almonds, peanuts, pistachios, chia seeds, and ground flaxseeds.
  • These can be served as snacks, salads, mixed in side dishes, topping, or added to unsweetened yogurt or oatmeal.

Fatty fish

  • Omega-3 fatty acids help reduce inflammation.
  • Examples include salmon, cod, rainbow trout, mackerel, and sardines.
  • These can be baked, sauteed, grilled, mixed into salads, and stir fry.

Avoid These Foods

When making lifestyle adjustments for a spondylitis anti-inflammation diet, focus on reducing or removing processed foods and saturated fats. These include:

  • Sugars from all sources like soda, sugary drinks, shakes, candy, and desserts.
  • Trans fats, like those in fried foods like chips and fries.
  • Starches, such as found in potatoes.
  • Refined carbohydrates, processed grains that include white bread, and pastries.
  • Red meat.
  • Gluten.
  • Dairy.
  • Eggs.

Individuals may not be symptomatic with certain foods, but that doesn’t mean the foods should be consumed. Gluten, dairy, and eggs can cause potential problems as they compromise the gut and the immune system. These can set back the individual’s healing or remission.

Body Composition

What Happens To The Body When Eating Fruit

Fruit is made up of simple sugar called fructose, providing the body with a carbohydrate energy source. The natural sugar the body gets from a piece of fruit is not the same as processed fructose added to processed products like fructose corn syrup. Processed products are typically filled with empty calories and very little nutrition. When the body has fruit, the liver processes fructose before getting absorbed through the small intestine. Research shows that exposing the gut to more fiber-rich foods like fruit helps the gut achieve an anti-obese condition by increasing the good bacteria and reducing the obese bacteria. Essential nutrients from fruit include:

  • Folate
  • Vitamin C
  • Vitamin B1

The USDA recommends making half of each meal/plate be fruit and vegetables.

References

Harvard Health Publishing. (November 16, 2021) “Foods that Fight Inflammation.” www.health.harvard.edu/staying-healthy/foods-that-fight-inflammation

Macfarlane, Tatiana V et al. “Relationship between diet and ankylosing spondylitis: A systematic review.” European journal of rheumatology vol. 5,1 (2018): 45-52. doi:10.5152/eurjrheum.2017.16103

Nielsen, Forrest H. “Magnesium deficiency and increased inflammation: current perspectives.” Journal of inflammation research vol. 11 25-34. January 18 2018, doi:10.2147/JIR.S136742

Rashid T, Wilson C, Ebringer A. The Link between Ankylosing Spondylitis, Crohn’s Disease, Klebsiella, and Starch Consumption. Clin Dev Immunol. 2013;2013:872632. doi: 10.1155/2013/872632.

Sharma, Satya P et al. “Paradoxical Effects of Fruit on Obesity.” Nutrients vol. 8,10 633. 14 Oct. 2016, doi:10.3390/nu8100633

van Buul, Vincent J et al. “Misconceptions about fructose-containing sugars and their role in the obesity epidemic.” Nutrition research reviews vol. 27,1 (2014): 119-30. doi:10.1017/S0954422414000067

Regenerative HCTP Therapy In Neurodegenerative Disorders

By
Dr. Alex Jimenez
-

Introduction

The brain’s primary function in the central nervous system is to transport and transmit neuron signals all throughout the entire body. These neuron signals help the body, gut, immune, endocrine, and musculoskeletal systems do their jobs properly and send the information back to the brain. When there are disruptors that enter the body and attach to the neuron signals, they can disrupt the signals while traveling to the brain. When this happens, the brain will develop neurodegenerative disorders over time and cause havoc on the body making it dysfunctional. There are many therapeutic ways to dampen the effects of neurodegenerative disorders and one of them is through regenerative HCTP therapy. In this article, we will be taking a look at what is the pathology of neurodegenerative disorders and how regenerative HCTP therapy can affect neurodegenerative disorders. By referring patients to qualified and skilled providers who specialized in neurological services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

What Is Neurodegenerative Disease?

 

According to WHO global study, 8 out of 10 disorders in the 3 highest disability classes are neurologic problems. Research studies have found that neurodegenerative diseases occur when the brain’s nerve cells start to lose function and die over time. Neurodegenerative diseases can vary from the symptoms that a person is experiencing and can be numerous risk factors as well. All over the world, there are over 276 million people that are disabled due to neurodegenerative diseases since it is a progressive age disease. Other studies have found that neurodegenerative diseases can be frequently observed due to ischemic, metabolic, toxic, infectious, and traumatic insults of the brain. As many people start to live longer, many neurodegenerative diseases will begin to increase over time due to age.

 

The Pathology of Neurodegenerative Disease

The pathology of neurodegenerative diseases can be many factors that the body has gone through. Some of these factors that can cause neurodegenerative diseases to rise include:

  • Reactive Oxygen Species (ROS) generation-causing chronic inflammation
  • Proteasome complex impairment
  • Mitochondrial function impairment
  • Toxic protein aggregation
  • Neurotoxic oligomers
  • Genetic factors

Studies have found that with the pathology of neurodegenerative diseases is often characterized by a progressive loss of selectively vulnerable population of neurons in the brain. Now, this is different than regular disruptors due to the neuronal loss from metabolic or toxic disorders that a person may already have with their current lifestyle. Other factors that can cause the pathology of neurodegenerative diseases to develop over time are an unhealthy lifestyle like not getting enough exercise, eating nutritional foods, or not moving around a lot can cause the cognitive functions in the brain to shrink slowly and develop into cognitive dysfunction over time.

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

HCTP (human cellular tissue products) or stem cells* are part of regenerative cellular treatment that both international and nationally affiliated clinics and distribution organizations use to help boost the body’s own natural healing process. HCTP can help individuals by repairing and regenerating damaged cells, diseased tissues, and organs back to their original state and function in the body. As more and upcoming research discusses the beneficial properties of HCTP, many individuals will begin on their wellness journey without being in chronic pain.

HCTP In Neurodegenerative Diseases

 

As stated earlier, HCTP or human cellular tissue products are used in both international and nationally affiliated clinics and distribution organizations that are specialized in this type of therapeutic treatment for individuals that are suffering from neurodegenerative diseases. Research studies have found that regenerative HCTP therapy has dampened the effects of neurodegenerative diseases from progressing further by regenerating the cellular structure and function of neurons in the brain. Some of the precise mechanisms of HCTP therapy for neurodegenerative diseases are still unknown but the beneficial factors that HCTP can offer include:

  • Growth factor secretion
  • Glial cell-derived neurotrophic factor (GDNF)
  • Vascular endothelial growth factor (VEGF)
  • Brain-derived neurotrophic factor (BDNF)
  • Neuroinflammation attenuation
  • Exosome and miRNA secretion
  • Mitochondria donation

Other research studies have found that regenerative HCTP therapy has the capability to repair injured neuronal tissues in the brain. HCTP actually provides the existing healthy neurons and glial cells protection from any further damage that can harm the brain.

 

HCTP & Parkinson’s

 

Research studies have found that Parkinson’s disease is one of the most insidious neurodegenerative diseases worldwide. However, with the use of regenerative HCTP therapy, many of the damaged neuronal will be able to regenerate. HCTP can help with the secretion of neurotrophic growth factors while also modulating the immune system via direct cell-to-cell interactions and aid wound healing. Other research studies have found that regenerative HCTP can improve neuronal health by mitochondrial donation and affect DAergic neurons via prostaglandin E2 and its signaling pathway by releasing dopamine by depolarizing potassium channels and dampening the effects of Parkinson’s.

 

HCTP & Stroke

When individuals suffer from a stroke, their entire outlook on life will begin to plummet as they try to piece themselves back together. Research studies have found that since inflammation is part of a major pathological event that follows an ischemic stroke, regenerative HCTP therapy can help dampen the effects of chronic neuroinflammation to the brain. When inflammation starts to infiltrate into the brain that suffered from a stroke, it can cause a disruption to the blood-brain barrier, which causes the pro-inflammatory cytokines to be released and infiltrate the immune cells. Other research studies show that the ischemic tissues can help enhanced HCTP recruitment from peripheral blood and are associated with enhanced neurogenesis, angiogenesis, and synaptogenesis. Other beneficial results that HCTP can provide to minimized the effects of a stroke are:

  • Inflammation attenuating
  • Attenuated neuronal death by suppressing activated microglia
  • Scar thickness reduction
  • Autophagy enhancing
  • Microenvironmental/metabolic profiles normalization

 

Conclusion

All in all, with many more research studies about the beneficial uses of HCTP, there are still ways to help dampen the effects of neurodegenerative diseases that many individuals can do. Either eating the right amount of foods that are filled with vitamins and minerals can help dampen inflammation in the body or exercising both mentally and physically can improve cognitive function by making the brain work on remembering what the person is doing can help the brain stay healthy and young. When neurodegenerative diseases start to affect the brain, it can cause symptoms of dementia, Alzheimer’s, or Parkinson’s’ to worsen over time. By incorporating therapeutic treatments like regenerative HCTP therapy into a person’s wellness journey can be beneficial to the individual.

 

References

Chang, Ying-Chao, et al. “Regenerative Therapy for Stroke.” Cell Transplantation, U.S. National Library of Medicine, 2007, pubmed.ncbi.nlm.nih.gov/17474298/.

Dugger, Brittany N, and Dennis W Dickson. “Pathology of Neurodegenerative Diseases.” Cold Spring Harbor Perspectives in Biology, Cold Spring Harbor Laboratory Press, 5 July 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5495060/.

Díaz, Mariacruz L. “Regenerative Medicine: Could Parkinson’s Be the First Neurodegenerative Disease to Be Cured?” Future Science OA, Future Science Ltd, 10 Oct. 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6787491/.

Professionals, NIEHS. “Neurodegenerative Diseases.” National Institute of Environmental Health Sciences, U.S. Department of Health and Human Services, 11 Feb. 2022, www.niehs.nih.gov/research/supported/health/neurodegenerative/index.cfm.

Przedborski, Serge, et al. “Neurodegeneration: What Is It and Where Are We?” The Journal of Clinical Investigation, American Society for Clinical Investigation, Jan. 2003, www.ncbi.nlm.nih.gov/pmc/articles/PMC151843/.

Rajkovic, Olivera, et al. “Regenerative Medicine Therapies for Targeting Neuroinflammation After Stroke.” Frontiers in Neurology, Frontiers Media S.A., 3 Sept. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6129611.

Sakthiswary, Rajalingham, and Azman Ali Raymond. “Stem Cell Therapy in Neurodegenerative Diseases: From Principles to Practice.” Neural Regeneration Research, Medknow Publications & Media Pvt Ltd, 15 Aug. 2012, www.ncbi.nlm.nih.gov/pmc/articles/PMC4302533/.

Sivandzade, Farzane, and Luca Cucullo. “Regenerative Stem Cell Therapy for Neurodegenerative Diseases: An Overview.” International Journal of Molecular Sciences, U.S. National Library of Medicine, 22 Feb. 2021, pubmed.ncbi.nlm.nih.gov/33671500/.

Yasuhara, Takao, et al. “Regenerative Medicine for Parkinson’s Disease.” Neurologia Medico-Chirurgica, The Japan Neurosurgical Society, 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4533405.

Disclaimer

Peptides For Neurodegenerative Disorders

By
Dr. Alex Jimenez
-

Introduction

The central nervous system’s main function is to make sure that the neuron signals are being transmitted all over the entire body. These neuron signals make sure that not only the body is functioning properly but the gut, the immune system, the endocrine system, and even the brain itself are doing their jobs. These neuron signals must have a bidirectional connection with the brain in order to make the body move, feel and sense things throughout a person’s day. When there are unwanted pathogens that enter the body and attach themselves to the neuron signals, they can travel to the brain and cause neurodegenerative diseases to develop over time if they are not treated. Luckily there are some therapeutic options like peptide therapy to help dampen the effects of neurological diseases in the brain. In this article, we will be taking a look at what are peptides, how they affect neurodegenerative diseases, and how they help the brain. By referring patients to qualified and skilled providers who specialized in neurological services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

Download

What Are Peptides?

 

In the body, there are molecules and antibodies that make sure that the body is functioning properly. Research studies have shown that peptides represent a unique class of pharmaceuticals compounds that are the foundation of all cellular processes. Peptides have been on the “fringes” of medicine until recently. In the past, they had a few problems that made them unaffordable due to their high cost, limited availability, and their short half-lives. However, that changed as peptides became more Pharma driven, have improved the bioavailability, and have recombinant technology and genetic engineering. Other studies have shown that peptides have been receiving increased interest since they possess favorable tissue penetration and the capability to engage with endogenous receptors in the body. What this means is that peptides can be versatile tools to help release the active components from food protein sources and provide the body health benefits that it needs.

Peptides For Neurological Disorders

Since neurological disorders are selective and progressive in the brain, research studies have found that peptides can provide therapeutic mechanisms that may be effective in dampening the symptoms and slowing down the onset progression of neurodegenerative disorders. Other beneficial factors that peptides can provide to the body include:

Other research studies have shown that since peptides are small molecules that are composed of amino acids that are linked to peptide bonds, they have the ability to reach different locations in the body that are complicated to access and provide treatment to neurological disorders.

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

Stem cells* or HCTP (human cellular tissue products) are a form of regenerative medicine that helps boost the body’s own natural healing process. Both international and nationally affiliated clinics and distribution organizations use HCTP to help repair and regenerate damaged cells, tissues, and organs back to their original state and function in the body. With more and upcoming research that informs individuals about the benefits of HCTP, many individuals can become pain-free and continue on their wellness journey.

GH & The Brain

 

GH receptor and GH (growth hormone) themselves are expressed widely in the brain and studies have shown that growth hormone replacement therapy can affect the cerebrospinal fluid levels for various hormones and neurotransmitters but also provide beneficial effects for cognitive function in the brain. Growth hormones have been reported to alter:

  • Neurogenesis
  • Myelin synthesis
  • Dendritic branching
  • Neural HCTP cells which are activated by GH

Growth hormones have also occurred in the hippocampus in response to a memory task since the cognitive domains are grouping them as either “crystallized” or “fluid” intelligence (short-termed or long-termed memory. Other studies have found that growth hormones can help with the development and function of the brain since growth hormones help with activating neural HCTP cells and downstream IGF‐1, IGF‐2. Several studies have shown a correlation between plasma IGF‐I concentrations and performance on tests of fluid intelligence, suggesting that GH may play a role in the maintenance of fluid intelligence.

 

IGF-1

Insulin‐like growth factor 1 (IGF1) is a polypeptide hormone that is structurally similar to insulin. It is central to the somatotropic axis, acting downstream of growth hormone (GH), and activates both the mitogen‐activated protein (MAP) kinase and PI3K signaling pathways. IGF-1 acts in almost every
tissue in the body to promote tissue growth and maturation through upregulation of anabolic processes. Studies have shown that IGF-1 is secreted by the liver and is transported to other tissues in the body while acting as an endocrine hormone. Since IGF1 expression levels decrease again later in life, low‐dose IGF1 treatment triggered a small increase in the differentiation of neuronal progenitors into neurons. While other studies have found that IGF1 signaling is key in promoting organized adult hippocampal neurogenesis due to the neurotrophic effects of IGF1 signaling, giving evidence for promotion of neurogenesis, development and maturation, myelination, prolonged survival, and resistance to injury, and the levels do decrease later in life.

 

Thymosin Alpha 1

 

Research shows that Thymosin Alpha 1 is a synthetic thymic peptide that naturally occurs in the thymus, while also being recognized to modify, enhance, and restore immune function in the body. Thymosin Alpha 1 contains 28 amino acids while promoting T cell differentiation and maturation in vivo and in vitro data while balancing the Th1/Th2 responses in the body. Other research studies have found that since the immune system plays an essential role in brain development, Thymosin Alpha 1 helps with neuronal plasticity and behavioral function as well as inhibiting viral replication as an antioxidant. This peptide also enhances dendritic cells and antibody responses while blocking steroid‐induced apoptosis of thymocytes with its anti-tumor effects plus providing protection against oxidative damage to the brain.

 

Conclusion

All in all, peptides are highly important for brain development and function as the central nervous system is responsible for transmitting neuron signals all throughout the entire body. When there are unwanted pathogens that start to attach themselves to the neuron signals, they can travel up to the brain and cause neurodegenerative disorders to the brain. Utilizing therapeutic treatments to help dampen the effects of neurodegenerative disorders and maintain the brain’s cognitive function, can help individuals continue on their wellness journey and be pain-free.

 

References

Dominari, Asimina, et al. “Thymosin Alpha 1: A Comprehensive Review of the Literature.” World Journal of Virology, Baishideng Publishing Group Inc, 15 Dec. 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7747025/.

Dominari, Asimina, et al. “Thymosin Alpha 1: A Comprehensive Review of the Literature.” World Journal of Virology, Baishideng Publishing Group Inc, 15 Dec. 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7747025/.

F;, Nyberg. “Growth Hormone in the Brain: Characteristics of Specific Brain Targets for the Hormone and Their Functional Significance.” Frontiers in Neuroendocrinology, U.S. National Library of Medicine, Oct. 2000, pubmed.ncbi.nlm.nih.gov/11013068/.

Laron, Z. “Insulin-like Growth Factor 1 (IGF-1): A Growth Hormone.” Molecular Pathology : MP, British Medical Journal Publishing Group, Oct. 2001, www.ncbi.nlm.nih.gov/pmc/articles/PMC1187088/.

Lee, Andy Chi-Lung, et al. “A Comprehensive Review on Current Advances in Peptide Drug Development and Design.” International Journal of Molecular Sciences, MDPI, 14 May 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6566176/.

Martínez-Villaluenga, Cristina, and Blanca Hernández-Ledesma. “Peptides for Health Benefits 2019.” International Journal of Molecular Sciences, MDPI, 6 Apr. 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7178072/.

Tiwari, Shashi Kant, and Rajnish K Chaturvedi. “Peptide Therapeutics in Neurodegenerative Disorders.” Current Medicinal Chemistry, U.S. National Library of Medicine, 2014, pubmed.ncbi.nlm.nih.gov/24533803/.

Wrigley, Sarah, et al. “Insulin-like Growth Factor 1: At the Crossroads of Brain Development and Aging.” Frontiers in Cellular Neuroscience, Frontiers Media S.A., 1 Feb. 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5285390/.

Yadav, Asmita, et al. “Peptide-Based Therapy for Neurological Disorders.” Current Protein & Peptide Science, U.S. National Library of Medicine, 27 Dec. 2021, pubmed.ncbi.nlm.nih.gov/34544337/.

Disclaimer

Elderly Sciatica

By
Dr. Alex Jimenez
-
Sciatica nerve pain. Senior Woman with Pain in Lower Back.

As individual bodies age, the nerves and muscles begin to degenerate, especially in the lower spinal region. This can cause sciatic pain and muscle weakness. Elderly sciatica is very common as the nerves and muscles have gone through a lot. Bending, lifting, carrying, reaching, twisting, and natural wearing and tearing make the sciatic nerve and surrounding muscles prone to injury. For overweight seniors, the risk of developing sciatica is higher.

Elderly Sciatica

Elderly Sciatica

The main reason for elderly sciatica is that as the body ages, the discs/cartilage between the vertebrae/bones in the spine dry out, losing their cushioning ability, which can lead to the bones shifting out of place more easily, rubbing against each other, and compressing nerves. On average, the body loses about 1 centimeter in height every ten years after 40.

Risk Factors

Diabetes

  • Diabetes affects the entire body.
  • Not keeping blood sugar in check can cause widespread symptoms that affect the nerves and organs.
  • Individuals with diabetes have an increased risk of developing sciatica and other nerve-damaging disorders.

Genetics

Controllable Risk Factors

Physical Activity

  • Sedentary and highly active lifestyles can cause sciatica.
  • Individuals who are highly sedentary have a greater risk of developing elderly sciatica.
  • Individuals who are highly active and do heavy lifting are also at risk because the activity increases the risk for a back injury.

Weight

  • The more overweight an individual is, the more at risk for developing sciatica.
  • The extra weight pushes on the spine and causes it to compress.
  • As the spine compresses, it can rub against the nerves causing irritation or pinch the nerves causing numbness, tingling, stinging, and pain.

Menopause

  • Menopause can lead to bone loss, causing nerve irritation and nerve damage.
  • If going or have gone through menopause, then it is essential to talk to a doctor about bone loss.
  • Individuals may need to start taking calcium or vitamin D supplements to keep their bones healthy.

Chiropractic

  • With chiropractic, elderly individuals can attain better quality sleep, improved mood, and increased energy levels.
  • A chiropractic physical therapy team can develop a specialized/customized treatment plan for preventive and palliative care.

Body Composition

Sarcopenia

Sarcopenia affects the elderly population’s mortality, cognitive function, and quality of life. As the elderly population is living longer, preservation of lean mass becomes an integral part of maintaining an individual’s independence. Loss of muscle in the arms and legs is linked to decreased mobility, increased risk of falls, and prolonged hospital stays. Falls and fractures often result in a cycle of muscle deterioration. InBody can help track body composition changes and help to minimize muscle wasting and risk of impaired mobility.

References

Aggarwal, Sameer, and Nityanand. “Calcium and vitamin D in postmenopausal women.” Indian journal of endocrinology and metabolism vol. 17,Suppl 3 (2013): S618-20. doi:10.4103/2230-8210.123549

Dougherty, Paul E et al. “The role of chiropractic care in older adults.” Chiropractic & manual therapies vol. 20,1 3. 21 Feb. 2012, doi:10.1186/2045-709X-20-3

Ferreira, Manuela L, and Andrew McLachlan. “The Challenges of Treating Sciatica Pain in Older Adults.” Drugs & aging vol. 33,11 (2016): 779-785. doi:10.1007/s40266-016-0404-z

Kherad, Mehrsa et al. “Risk factors for low back pain and sciatica in elderly men-the MrOS Sweden study.” Age and aging vol. 46,1 (2017): 64-71. doi:10.1093/ageing/afw152

Light Therapy For Brain Disease | Part 2

By
Dr. Alex Jimenez
-

Introduction

The brain is part of the central nervous system and its primary function is to transmit neuron signals all throughout the entire body. The neuron signals make sure that not only the body is functioning, but that the heart is beating regularly, the gut is digesting the food, blood pressure and the feeling sensations are normal. When there are unwanted pathogens that attach themselves to the neuron signals and travel to the brain, can develop into neurodegenerative diseases over time. Luckily there are therapeutic ways to dampen the effects of neurodegenerative diseases and one of them is low laser light therapy. In this 2 part series, we will be taking a look at how light therapy can be beneficial for individuals that are suffering from neurodegenerative diseases. Part 1 took a look at how different microbial infections are involved in neurodegeneration to the brain. By referring patients to qualified and skilled providers who specialized in neurological services. To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination. We find that education is the key to asking valuable questions to our providers. Dr. Jimenez DC provides this information as an educational service only. Disclaimer

 

Can my insurance cover it? Yes, in case you are uncertain here is the link to all the insurance providers we cover. If you have any questions, please call Dr. Jimenez at 915-850-0900.

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Low-Laser Therapy For The Brain

Seeing how neurological and neuropsychiatric diseases are degenerative in nature that are characterized by protein aggregation, there are novel methods to treat protein aggregation and downstream issues since the human body utilizes light energy to catalyze chemical reactions and help dampen the effects of protein aggregation. This is referred to as “photobiomodulation” or low laser therapy. Low laser therapy has endogenous molecules that have different absorption peaks throughout the electromagnetic spectrum, thus resulting in different physiological effects:

  • Melanin (~340nm)
  • Unbound hemoglobin (~430nm)
  • Water (~1900nm)
  • Reduced mitochondrial Cytochrome C (~605nm)

Studies have found that low laser therapy when applied to the forehead and scalp areas of an individual with traumatic brain injury has helped improve cognitive function in the brain. By altering human physiology with light is a potent therapeutic for numerous conditions as the common “therapeutic range” of laser wavelengths for treating disease is from ~600nm to 1000nm. These wavelengths readily penetrate tissues while hitting disease-relevant biological targets.

The Mechanisms Of LLT

 

Research studies show that low laser therapy does exert beneficial effects on the motor and histopathological outcomes after traumatic brain injury, while also improving cognitive recovery and limiting the inflammation after the injury. The mechanisms at cellular and molecular levels of low laser therapy can help increase ATP production, release nitric oxide, changes the body’s gene expression while normalizing the membrane potentials via activation of light-sensitive ion channels. Even though a functional brain can change from photobiomodulation, it’s not all about increasing blood circulation. Other beneficial factors that low laser therapy include:

  • Heat shock protein induction
  • Angiogenesis and increased blood flow
  • Reduced pain and inflammation
  • Increased tissue growth
  • Increased HCTP proliferation
  • Reduced tissue atrophy (due to lower apoptosis rate)
  • Improvement in motor function in skeletal muscle

Other studies have found that the application of low laser therapy on the scalp can help improve mitochondrial function and increase adenosine triphosphate (ATP), which both are important for cellular metabolism. This allows nitric oxide to be released locally and increases the regional cerebral blood flow to the brain.

HCTP Therapy

Tony Robbins finds secret to eliminating back pain

HCTP (human cellular tissue products) or stem cells* are part of regenerative cellular treatment that both international and nationally affiliated clinics and distribution organizations utilize to help boost the body’s own natural healing process. HCTP is used to repair and regenerate damaged cells, diseased tissues, and organs back to their original functioning state in the body. With more and upcoming research about the beneficial properties of HCTP, many individuals can begin their wellness journey pain-free.

The “Rainbow Effect”

Known as the “Rainbow Effect,” chromotherapy is a method of treatment that uses the color spectrum of electromagnetic radiation to help diseases as studies show. With low laser therapy helping cognitive function, many healthcare professionals use the color light wavelengths to help the body feel less pain. Each of the different electromagnetic wavelengths is correlated to the colors of the rainbow and provides different frequencies to tackle what ailments a person is feeling.  Some of the other treatments that chromotherapy and low laser therapy offer include:

  • Methylene Blue
  • UV Blood Irradiation 
  • Antimicrobial Photodynamic Therapy

 

Methylene Blue

 

Multi-use dye has been historically used for malaria and methemoglobinemia and methylene blue acts as an electron donor for ETC Complex IV. It can absorb light like an endogenous cytochrome oxidase to increase catalysis while also boosting oxygen consumption and ATP output in the body. Research studies have found that methylene blue can cross the blood-brain barrier and form a reversible reduce-oxidation system that has auto-oxidizing capacity. With methylene blue inhibiting recombinant protein aggregation in vitro, even when added to preformed oligomers and fibrils. Other studies have found that methylene blue can help improve memory retention of extinction of fear conditioning in the brain. It can help combat impaired mitochondrial metabolism with its antioxidant effects and increased survival of primary cortical neurons transduced with mutant Htt, reduced neurodegeneration.

 

UV Blood Irradiation

Ultraviolet blood irradiation (UBI) was extensively used in the 1940s and 1950s to treat many diseases
including septicemia, pneumonia, tuberculosis, arthritis, asthma, and even poliomyelitis. The early studies were carried out by several physicians in the USA and published in the American Journal of Surgery. However, with the development of antibiotics, UBI use declined and it has now been called “the cure that time forgot”. Research studies have found that UV blood irradiation has been used as an alternative approach to treating infections as an immuno-modulating therapy while also normalizing blood parameters. The amazing results are thought to come from effects on the immune system by:

  • Increased phagocytosis
  • Increases secretion of NO and reactive nitrogen species
  • Deactivation of circulating lymphocytes may reduce inflammation
  • Transient increase in ROS activates antioxidant defenses

 

Antimicrobial Photodynamic Therapy

Antimicrophotodynamic therapy is a therapeutic approach that can kill microorganisms by combining light (of a specific wavelength), a light-sensitive substance (photosensitizer), and oxygen effective against drug-resistant pathogens. Studies have found that antimicrobial photodynamic therapy has been used to treat infections that are in the body cavities and is an anon-toxic dye that binds to microbes in the body with few side effects and is cost-efficient.

 

As studies show that photosensitizers provide bacterial inactivation due to their interaction with oxygen and ROS. Since photosensitizers absorb photons and are excited to a highly reactive state, their reaction with ambient oxygen generates reactive oxygen species and causes irreparable damage to microbe DNA and cell walls to their death.

 

Conclusion

All in all, it is important to find many therapeutic ways to treat numerous brain disorders and diseases that can cause the brain to be dysfunctional and cause the body to develop chronic illnesses. Since the brain is part of the central nervous system, the neuron signals need that bidirectional connection with the body, the organs, and the brain in order to function. Making small changes in a person’s lifestyle and eating habits can improve cognitive function and allow individuals to be well off in their wellness journey.

 

References

Azeemi, Samina T Yousuf, and S Mohsin Raza. “A Critical Analysis of Chromotherapy and Its Scientific Evolution.” Evidence-Based Complementary and Alternative Medicine: ECAM, Oxford University Press, Dec. 2005, www.ncbi.nlm.nih.gov/pmc/articles/PMC1297510/.

Hamblin, Michael R, and Tayyaba Hasan. “Photodynamic Therapy: A New Antimicrobial Approach to Infectious Disease?” Photochemical & Photobiological Sciences: Official Journal of the European Photochemistry Association and the European Society for Photobiology, U.S. National Library of Medicine, May 2004, www.ncbi.nlm.nih.gov/pmc/articles/PMC3071049/.

Hamblin, Michael R. “Ultraviolet Irradiation of Blood: ‘The Cure That Time Forgot’?” Advances in Experimental Medicine and Biology, U.S. National Library of Medicine, 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC6122858/.

Khuman, Jugta, et al. “Low-Level Laser Light Therapy Improves Cognitive Deficits and Inhibits Microglial Activation after Controlled Cortical Impact in Mice.” Journal of Neurotrauma, Mary Ann Liebert, Inc., 20 Jan. 2012, www.ncbi.nlm.nih.gov/pmc/articles/PMC3261787/.

Naeser, Margaret A, et al. “Improved Cognitive Function after Transcranial, Light-Emitting Diode Treatments in Chronic, Traumatic Brain Injury: Two Case Reports.” Photomedicine and Laser Surgery, Mary Ann Liebert, Inc., May 2011, www.ncbi.nlm.nih.gov/pmc/articles/PMC3104287/.

Naeser, Margaret A, et al. “Significant Improvements in Cognitive Performance Post-Transcranial, Red/near-Infrared Light-Emitting Diode Treatments in Chronic, Mild Traumatic Brain Injury: Open-Protocol Study.” Journal of Neurotrauma, Mary Ann Liebert, Inc., 1 June 2014, www.ncbi.nlm.nih.gov/pmc/articles/PMC4043367/.

Pinto, Juliana Guerra, et al. “Efficiency of Antimicrobial Photodynamic Therapy with Photodithazine® on MSSA and MRSA Strains.” Antibiotics (Basel, Switzerland), MDPI, 17 July 2021, www.ncbi.nlm.nih.gov/pmc/articles/PMC8300773/.

Riha, Penny D, et al. “The Brain Metabolic Enhancer Methylene Blue Improves Discrimination Learning in Rats.” Pharmacology, Biochemistry, and Behavior, U.S. National Library of Medicine, Apr. 2007, www.ncbi.nlm.nih.gov/pmc/articles/PMC2040387/.

Rodriguez, Pavel, et al. “Methylene Blue Modulates Functional Connectivity in the Human Brain.” Brain Imaging and Behavior, U.S. National Library of Medicine, June 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5018244/.

Disclaimer

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Sciatica Specialist
STOP SUFFERING! We specialize in advanced non-surgical approaches in treating sciatica. Our focus is to stop the pain, remove the cause and prevent chronic recurrence of complex sciatica pain syndromes. We treat with advanced protocols and supportive care plans. Blessings - Dr. Alex Jimenez DC, MSACP, IFMCP, CIFM, ATN
Contact us: chat@elpasobackclinic.com
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